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Journal Abstract Search

286 related items for PubMed ID: 10376975

  • 1. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A.
    Br J Cancer; 1999 Jun; 80(8):1223-30. PubMed ID: 10376975
    [Abstract] [Full Text] [Related]

  • 2. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A, Leith MK, Curphey TJ, Doherty GP.
    Oncol Res; 1997 Jun; 9(6-7):371-82. PubMed ID: 9406243
    [Abstract] [Full Text] [Related]

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 4. [DT-diaphorase].
    Mikami K, Shirakusa T, Tsuruo T.
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
    [Abstract] [Full Text] [Related]

  • 5. Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents.
    Doherty GP, Leith MK, Wang X, Curphey TJ, Begleiter A.
    Br J Cancer; 1998 Apr; 77(8):1241-52. PubMed ID: 9579829
    [Abstract] [Full Text] [Related]

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  • 7. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL.
    Clin Cancer Res; 2001 May; 7(5):1313-9. PubMed ID: 11350900
    [Abstract] [Full Text] [Related]

  • 8. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S, Nishiyama M, Toge T.
    Hiroshima J Med Sci; 1995 Sep; 44(3):55-63. PubMed ID: 8567314
    [Abstract] [Full Text] [Related]

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  • 10. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 11. Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents.
    Begleiter A, Leith MK, Curphey TJ.
    Br J Cancer Suppl; 1996 Jul; 27():S9-14. PubMed ID: 8763837
    [Abstract] [Full Text] [Related]

  • 12. Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: implications for enzyme-directed bioreductive drug development.
    Phillips RM, Burger AM, Loadman PM, Jarrett CM, Swaine DJ, Fiebig HH.
    Cancer Res; 2000 Nov 15; 60(22):6384-90. PubMed ID: 11103802
    [Abstract] [Full Text] [Related]

  • 13. Alternative splicing and differential expression of DT-diaphorase transcripts in human colon tumors and in peripheral mononuclear cells in response to mitomycin C treatment.
    Yao KS, Godwin AK, Johnson C, O'Dwyer PJ.
    Cancer Res; 1996 Apr 15; 56(8):1731-6. PubMed ID: 8620484
    [Abstract] [Full Text] [Related]

  • 14. Lack of NQO1 induction in human tumor cells is not due to changes in the promoter region of the gene.
    Begleiter A, Lange L.
    Int J Oncol; 2002 Apr 15; 20(4):835-8. PubMed ID: 11894133
    [Abstract] [Full Text] [Related]

  • 15. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD, Murphy AM, Siegel D, Hargreaves RH, Butler J, Ross D.
    Mol Pharmacol; 1995 Sep 15; 48(3):499-504. PubMed ID: 7565631
    [Abstract] [Full Text] [Related]

  • 16. DT-diaphorase: a target for new anticancer drugs.
    Danson S, Ward TH, Butler J, Ranson M.
    Cancer Treat Rev; 2004 Aug 15; 30(5):437-49. PubMed ID: 15245776
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Dec 01; 50(23):7483-9. PubMed ID: 1701346
    [Abstract] [Full Text] [Related]

  • 18. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

  • 19. Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs.
    Powis G, Gasdaska PY, Gallegos A, Sherrill K, Goodman D.
    Anticancer Res; 1995 Feb 15; 15(4):1141-5. PubMed ID: 7653992
    [Abstract] [Full Text] [Related]

  • 20. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
    Kuehl BL, Buchwald M, Rauth AM.
    Oncol Res; 1993 Feb 15; 5(6-7):213-21. PubMed ID: 8123941
    [Abstract] [Full Text] [Related]

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