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382 related items for PubMed ID: 10390343

  • 1. The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.
    Erzberger JP, Wilson DM.
    J Mol Biol; 1999 Jul 09; 290(2):447-57. PubMed ID: 10390343
    [Abstract] [Full Text] [Related]

  • 2. Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.
    Nguyen LH, Barsky D, Erzberger JP, Wilson DM.
    J Mol Biol; 2000 May 05; 298(3):447-59. PubMed ID: 10772862
    [Abstract] [Full Text] [Related]

  • 3. Single-turnover analysis of mutant human apurinic/apyrimidinic endonuclease.
    Lucas JA, Masuda Y, Bennett RA, Strauss NS, Strauss PR.
    Biochemistry; 1999 Apr 20; 38(16):4958-64. PubMed ID: 10213597
    [Abstract] [Full Text] [Related]

  • 4. Intragenic suppression of an active site mutation in the human apurinic/apyrimidinic endonuclease.
    Izumi T, Malecki J, Chaudhry MA, Weinfeld M, Hill JH, Lee JC, Mitra S.
    J Mol Biol; 1999 Mar 19; 287(1):47-57. PubMed ID: 10074406
    [Abstract] [Full Text] [Related]

  • 5. Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures.
    Wilson DM.
    J Mol Biol; 2005 Feb 04; 345(5):1003-14. PubMed ID: 15644200
    [Abstract] [Full Text] [Related]

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  • 7. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions.
    Vidal AE, Boiteux S, Hickson ID, Radicella JP.
    EMBO J; 2001 Nov 15; 20(22):6530-9. PubMed ID: 11707423
    [Abstract] [Full Text] [Related]

  • 8. Novel role of tyrosine in catalysis by human AP endonuclease 1.
    Mundle ST, Fattal MH, Melo LF, Coriolan JD, O'Regan NE, Strauss PR.
    DNA Repair (Amst); 2004 Nov 02; 3(11):1447-55. PubMed ID: 15380100
    [Abstract] [Full Text] [Related]

  • 9. The role of Asn-212 in the catalytic mechanism of human endonuclease APE1: stopped-flow kinetic study of incision activity on a natural AP site and a tetrahydrofuran analogue.
    Kanazhevskaya LY, Koval VV, Lomzov AA, Fedorova OS.
    DNA Repair (Amst); 2014 Sep 02; 21():43-54. PubMed ID: 25038572
    [Abstract] [Full Text] [Related]

  • 10. Effects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1).
    Izumi T, Schein CH, Oezguen N, Feng Y, Braun W.
    Biochemistry; 2004 Jan 27; 43(3):684-9. PubMed ID: 14730972
    [Abstract] [Full Text] [Related]

  • 11. Characterization of amino acid substitutions that severely alter the DNA repair functions of Escherichia coli endonuclease IV.
    Yang X, Tellier P, Masson JY, Vu T, Ramotar D.
    Biochemistry; 1999 Mar 23; 38(12):3615-23. PubMed ID: 10090748
    [Abstract] [Full Text] [Related]

  • 12. Does the restriction endonuclease EcoRV employ a two-metal-Ion mechanism for DNA cleavage?
    Groll DH, Jeltsch A, Selent U, Pingoud A.
    Biochemistry; 1997 Sep 23; 36(38):11389-401. PubMed ID: 9298958
    [Abstract] [Full Text] [Related]

  • 13. A spin-labeled abasic DNA substrate for AP endonuclease.
    Kolaczkowski SV, Perry A, Mckenzie A, Johnson F, Budil DE, Strauss PR.
    Biochem Biophys Res Commun; 2001 Nov 02; 288(3):722-6. PubMed ID: 11676503
    [Abstract] [Full Text] [Related]

  • 14. Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.
    Daviet S, Couvé-Privat S, Gros L, Shinozuka K, Ide H, Saparbaev M, Ishchenko AA.
    DNA Repair (Amst); 2007 Jan 04; 6(1):8-18. PubMed ID: 16978929
    [Abstract] [Full Text] [Related]

  • 15. Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism.
    Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM, Rupp B.
    J Mol Biol; 2001 Apr 06; 307(4):1023-34. PubMed ID: 11286553
    [Abstract] [Full Text] [Related]

  • 16. Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases.
    Erzberger JP, Barsky D, Schärer OD, Colvin ME, Wilson DM.
    Nucleic Acids Res; 1998 Jun 01; 26(11):2771-8. PubMed ID: 9592167
    [Abstract] [Full Text] [Related]

  • 17. Site-directed mutagenesis of putative active site residues of MunI restriction endonuclease: replacement of catalytically essential carboxylate residues triggers DNA binding specificity.
    Lagunavicius A, Siksnys V.
    Biochemistry; 1997 Sep 16; 36(37):11086-92. PubMed ID: 9287151
    [Abstract] [Full Text] [Related]

  • 18. Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA.
    Marenstein DR, Wilson DM, Teebor GW.
    DNA Repair (Amst); 2004 May 04; 3(5):527-33. PubMed ID: 15084314
    [Abstract] [Full Text] [Related]

  • 19. 6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding.
    Bürgisser DM, Thöny B, Redweik U, Hess D, Heizmann CW, Huber R, Nar H.
    J Mol Biol; 1995 Oct 20; 253(2):358-69. PubMed ID: 7563095
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1.
    Kim WC, Berquist BR, Chohan M, Uy C, Wilson DM, Lee CH.
    J Mol Biol; 2011 Sep 02; 411(5):960-71. PubMed ID: 21762700
    [Abstract] [Full Text] [Related]

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