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228 related items for PubMed ID: 10393217

  • 1. Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs.
    Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW.
    J Lipid Res; 1999 Jul; 40(7):1317-27. PubMed ID: 10393217
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol.
    Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Huff MW.
    Biochim Biophys Acta; 1998 Jul 31; 1393(1):63-79. PubMed ID: 9714740
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of HMG-CoA reductase by atorvastatin decreases both VLDL and LDL apolipoprotein B production in miniature pigs.
    Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW.
    Arterioscler Thromb Vasc Biol; 1997 Nov 31; 17(11):2589-600. PubMed ID: 9409231
    [Abstract] [Full Text] [Related]

  • 4. The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs.
    Burnett JR, Telford DE, Barrett PH, Huff MW.
    Biochim Biophys Acta; 2005 Dec 30; 1738(1-3):10-8. PubMed ID: 16427354
    [Abstract] [Full Text] [Related]

  • 5. The magnitude of decrease in hepatic very low density lipoprotein apolipoprotein B secretion is determined by the extent of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibition in miniature pigs.
    Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW.
    Endocrinology; 1999 Nov 30; 140(11):5293-302. PubMed ID: 10537160
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet.
    Huff MW, Telford DE, Barrett PH, Billheimer JT, Gillies PJ.
    Arterioscler Thromb; 1994 Sep 30; 14(9):1498-508. PubMed ID: 8068612
    [Abstract] [Full Text] [Related]

  • 7. Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
    Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K.
    Biochem Pharmacol; 2002 Feb 01; 63(3):349-60. PubMed ID: 11853686
    [Abstract] [Full Text] [Related]

  • 8. Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol.
    Riddell D, Bright CP, Burton BJ, Bush RC, Harris NV, Hele D, Moore UM, Naik K, Parrott DP, Smith C, Williams RJ.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1177-86. PubMed ID: 8937424
    [Abstract] [Full Text] [Related]

  • 9. ApoB100 secretion from HepG2 cells is decreased by the ACAT inhibitor CI-1011: an effect associated with enhanced intracellular degradation of ApoB.
    Wilcox LJ, Barrett PH, Newton RS, Huff MW.
    Arterioscler Thromb Vasc Biol; 1999 Apr 25; 19(4):939-49. PubMed ID: 10195921
    [Abstract] [Full Text] [Related]

  • 10. Pharmacology of the ACAT inhibitor avasimibe (CI-1011).
    Llaverías G, Laguna JC, Alegret M.
    Cardiovasc Drug Rev; 2003 Apr 25; 21(1):33-50. PubMed ID: 12595916
    [Abstract] [Full Text] [Related]

  • 11. Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
    Post SM, Zoeteweij JP, Bos MH, de Wit EC, Havinga R, Kuipers F, Princen HM.
    Hepatology; 1999 Aug 25; 30(2):491-500. PubMed ID: 10421659
    [Abstract] [Full Text] [Related]

  • 12. Mevinolin and cholestyramine inhibit the direct synthesis of low density lipoprotein apolipoprotein B in miniature pigs.
    Huff MW, Telford DE, Woodcroft K, Strong WL.
    J Lipid Res; 1985 Oct 25; 26(10):1175-86. PubMed ID: 3906004
    [Abstract] [Full Text] [Related]

  • 13. The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits.
    Bocan TM, Krause BR, Rosebury WS, Mueller SB, Lu X, Dagle C, Major T, Lathia C, Lee H.
    Arterioscler Thromb Vasc Biol; 2000 Jan 25; 20(1):70-9. PubMed ID: 10634802
    [Abstract] [Full Text] [Related]

  • 14. Acyl coenzyme A: cholesterol acyltransferase inhibition and hepatic apolipoprotein B secretion.
    Burnett JR, Wilcox LJ, Huff MW.
    Clin Chim Acta; 1999 Aug 25; 286(1-2):231-42. PubMed ID: 10511295
    [Abstract] [Full Text] [Related]

  • 15. Metabolic behavior of hepatic VLDL and plasma LDL apoB-100 in African green monkeys.
    Marzetta CA, Johnson FL, Zech LA, Foster DM, Rudel LL.
    J Lipid Res; 1989 Mar 25; 30(3):357-70. PubMed ID: 2723543
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of action of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor on apolipoprotein B-100 kinetics in visceral obesity.
    Chan DC, Watts GF, Barrett PH, Mori TA, Beilin LJ, Redgrave TG.
    J Clin Endocrinol Metab; 2002 May 25; 87(5):2283-9. PubMed ID: 11994377
    [Abstract] [Full Text] [Related]

  • 17. Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice.
    Delsing DJ, Offerman EH, van Duyvenvoorde W, van Der Boom H, de Wit EC, Gijbels MJ, van Der Laarse A, Jukema JW, Havekes LM, Princen HM.
    Circulation; 2001 Apr 03; 103(13):1778-86. PubMed ID: 11282910
    [Abstract] [Full Text] [Related]

  • 18. A novel inhibitor of oxidosqualene:lanosterol cyclase inhibits very low-density lipoprotein apolipoprotein B100 (apoB100) production and enhances low-density lipoprotein apoB100 catabolism through marked reduction in hepatic cholesterol content.
    Telford DE, Lipson SM, Barrett PH, Sutherland BG, Edwards JY, Aebi JD, Dehmlow H, Morand OH, Huff MW.
    Arterioscler Thromb Vasc Biol; 2005 Dec 03; 25(12):2608-14. PubMed ID: 16210564
    [Abstract] [Full Text] [Related]

  • 19. Reduction in visceral adipose tissue is associated with improvement in apolipoprotein B-100 metabolism in obese men.
    Riches FM, Watts GF, Hua J, Stewart GR, Naoumova RP, Barrett PH.
    J Clin Endocrinol Metab; 1999 Aug 03; 84(8):2854-61. PubMed ID: 10443691
    [Abstract] [Full Text] [Related]

  • 20. Dietary fish oil plus lovastatin decreases both VLDL and LDL apo B production in miniature pigs.
    Huff MW, Telford DE, Barrett PH.
    Arterioscler Thromb; 1992 Aug 03; 12(8):902-10. PubMed ID: 1637788
    [Abstract] [Full Text] [Related]

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