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PUBMED FOR HANDHELDS

Journal Abstract Search


128 related items for PubMed ID: 10399839

  • 1. Synthesis of (1-azabicyclo[3.3.0]octanyl)methyl-substituted aromatic heterocycles and their muscarinic activity.
    Suzuki T, Uesaka H, Hamajima H, Ikami T.
    Chem Pharm Bull (Tokyo); 1999 Jun; 47(6):876-9. PubMed ID: 10399839
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological activity of the metabolites of N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate (SK-946).
    Suzuki T, Inagaki H, Hamajima H, Uesaka H, Hori K, Ikami T.
    Chem Pharm Bull (Tokyo); 1999 Jun; 47(6):880-3. PubMed ID: 10399840
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and muscarinic activity of a series of quinolines and naphthalenes with a 1-azabicyclo[3.3.0]octane moiety.
    Suzuki T, Usui T, Oka M, Suzuki T, Kataoka T.
    Chem Pharm Bull (Tokyo); 1998 Aug; 46(8):1265-73. PubMed ID: 9734314
    [Abstract] [Full Text] [Related]

  • 4. C(8) substituted 1-azabicyclo[3.3.1]non-3-enes and C(8) substituted 1-azabicyclo[3.3.1]nonan-4-ones: novel muscarinic receptor antagonists.
    Kim MG, Bodor ET, Wang C, Harden TK, Kohn H.
    J Med Chem; 2003 May 22; 46(11):2216-26. PubMed ID: 12747793
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and muscarinic activity of novel aniline derivatives with a 1-azabicyclo[3.3.0]octane moiety.
    Suzuki T, Oka M, Maeda K, Furusawa K, Uesaka H, Kataoka T.
    Chem Pharm Bull (Tokyo); 1999 Jan 22; 47(1):28-36. PubMed ID: 9987823
    [Abstract] [Full Text] [Related]

  • 6. (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.
    Fisher A, Brandeis R, Karton I, Pittel Z, Gurwitz D, Haring R, Sapir M, Levy A, Heldman E.
    J Pharmacol Exp Ther; 1991 Apr 22; 257(1):392-403. PubMed ID: 2019998
    [Abstract] [Full Text] [Related]

  • 7. Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane .
    Bymaster FP, Shannon HE, Rasmussen K, Delapp NW, Mitch CH, Ward JS, Calligaro DO, Ludvigsen TS, Sheardown MJ, Olesen PH, Swedberg MD, Sauerberg P, Fink-Jensen A.
    Eur J Pharmacol; 1998 Sep 04; 356(2-3):109-19. PubMed ID: 9774240
    [Abstract] [Full Text] [Related]

  • 8. Biochemical and behavioral characterization of a novel cholinergic agonist, SR 95639.
    Boast CA, Leventer S, Sabb A, Abelson M, Bender R, Giacomo D, Maurer S, McArthur S, Mehta O, Morris H.
    Pharmacol Biochem Behav; 1991 Jun 04; 39(2):287-92. PubMed ID: 1658814
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity studies of a series of 1-oxa-2,8-diazaspiro[4.5]decan-3-ones and related compounds as M1 muscarinic agonists.
    Tsukamoto S, Nagaoka H, Igarashi S, Wanibuchi F, Hidaka K, Tamura T.
    Chem Pharm Bull (Tokyo); 1995 Sep 04; 43(9):1523-9. PubMed ID: 7586076
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of 2-(3-substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8-azabicyclo [3.2.1]octanes and 2 alpha-(3-substituted-1,2,4-oxadiazol-5-yl)-8-methyl-8- azabicyclo[3.2.1]oct-2-enes as potential muscarinic agonists.
    Triggle DJ, Kwon YW, Abraham P, Rahman MA, Carroll FI.
    Pharm Res; 1992 Nov 04; 9(11):1474-9. PubMed ID: 1475236
    [Abstract] [Full Text] [Related]

  • 11. Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists.
    Lainé DI, Xie H, Buffet N, Foley JJ, Buckley P, Webb EF, Widdowson KL, Palovich MR, Belmonte KE.
    Bioorg Med Chem Lett; 2007 Nov 15; 17(22):6066-9. PubMed ID: 17911022
    [Abstract] [Full Text] [Related]

  • 12. Discriminative stimulus properties of the muscarinic receptor agonists Lu 26-046 and O-Me-THPO in rats: evidence for involvement of different muscarinic receptor subtypes.
    Arnt J, Lembøl HL, Meier E, Pedersen H.
    Eur J Pharmacol; 1992 Jul 21; 218(1):159-69. PubMed ID: 1397027
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and binding studies of some epibatidine analogues.
    Rádl S, Hezký P, Hafner W, Budesínský M, Hejnová L.
    Bioorg Med Chem Lett; 2000 Jan 03; 10(1):55-8. PubMed ID: 10636243
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of 1-azabicyclo[3.3.0]octane derivatives and their effects as piracetam-like nootropics.
    Oka M, Matsumoto Y, Hirooka K, Suzuki T.
    Chem Pharm Bull (Tokyo); 2000 Aug 03; 48(8):1121-4. PubMed ID: 10959574
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological studies on novel muscarinic agonists, 1-oxa-8-azaspiro[4.5]decane derivatives, YM796 and YM954.
    Wanibuchi F, Konishi T, Harada M, Terai M, Hidaka K, Tamura T, Tsukamoto S, Usuda S.
    Eur J Pharmacol; 1990 Oct 23; 187(3):479-86. PubMed ID: 1963596
    [Abstract] [Full Text] [Related]

  • 16. Down-regulation and desensitization of the muscarinic M1 and M2 receptors in transfected fibroblast B82 cells.
    Wei HB, Yamamura HI, Roeske WR.
    Eur J Pharmacol; 1994 Aug 16; 268(3):381-91. PubMed ID: 7805762
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and SAR of bulky 1-azabicyclo[2.2.1]-3-one oximes as muscarinic receptor subtype selective agonists.
    Tecle H, Lauffer DJ, Mirzadegan T, Moos WH, Moreland DW, Pavia MR, Schwarz RD, Davis RE.
    Life Sci; 1993 Aug 16; 52(5-6):505-11. PubMed ID: 8382765
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, and structure-activity relationship of tropane muscarinic acetylcholine receptor antagonists.
    Lainé DI, Wan Z, Yan H, Zhu C, Xie H, Fu W, Busch-Petersen J, Neipp C, Davis R, Widdowson KL, Blaney FE, Foley J, Bacon AM, Webb EF, Luttmann MA, Burman M, Sarau HM, Salmon M, Palovich MR, Belmonte K.
    J Med Chem; 2009 Aug 27; 52(16):5241-52. PubMed ID: 19630384
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and structural determination of stereoisomers of muscarinic ligands of the (3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicycloalkane type.
    Olesen PH, Sauerberg P, Petersen TG, Treppendahl S, Bentzen B, Deeter J, Ward JS, Mitch CH, Lehmann SV.
    Chirality; 1997 Aug 27; 9(8):739-49. PubMed ID: 9435099
    [Abstract] [Full Text] [Related]

  • 20. Interaction of a new potent anticholinesterasic compound (+/-)huprine X with muscarinic receptors in rat brain.
    Roman S, Vivas NM, Badia A, Clos MV.
    Neurosci Lett; 2002 Jun 07; 325(2):103-6. PubMed ID: 12044632
    [Abstract] [Full Text] [Related]


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