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122 related items for PubMed ID: 10400420

  • 1. Induction of apoptosis and differentiation by fludarabine in human leukemia cells (U937): interactions with the macrocyclic lactone bryostatin 1.
    Vrana JA, Wang Z, Rao AS, Tang L, Chen JH, Kramer LB, Grant S.
    Leukemia; 1999 Jul; 13(7):1046-55. PubMed ID: 10400420
    [Abstract] [Full Text] [Related]

  • 2. Effects of bryostatin 1 and calcium ionophore (A23187) on apoptosis and differentiation in human myeloid leukemia cells (HL-60) following 1-beta-D-arabinofuranosylcytosine exposure.
    Vrana JA, Rao AS, Wang Z, Jarvis WD, Grant S.
    Int J Oncol; 1998 Apr; 12(4):927-34. PubMed ID: 9499457
    [Abstract] [Full Text] [Related]

  • 3. Effect of AS101 on bryostatin 1-mediated differentiation induction, cell cycle arrest, and modulation of drug-induced apoptosis in human myeloid leukemia cells.
    Rao AS, Freemerman AJ, Jarvis WD, Chelliah J, Bear HD, Mikkelsen R, Grant S.
    Leukemia; 1996 Jul; 10(7):1150-8. PubMed ID: 8683995
    [Abstract] [Full Text] [Related]

  • 4. Evidence of a functional role for the cyclin-dependent kinase inhibitor p21(WAF1/CIP1/MDA6) in the reciprocal regulation of PKC activator-induced apoptosis and differentation in human myelomonocytic leukemia cells.
    Wang Z, Su ZZ, Fisher PB, Wang S, VanTuyle G, Grant S.
    Exp Cell Res; 1998 Oct 10; 244(1):105-16. PubMed ID: 9770354
    [Abstract] [Full Text] [Related]

  • 5. Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937).
    Vrana JA, Saunders AM, Chellappan SP, Grant S.
    Differentiation; 1998 May 10; 63(1):33-42. PubMed ID: 9615391
    [Abstract] [Full Text] [Related]

  • 6. Effect of bryostatin 1 on taxol-induced apoptosis and cytotoxicity in human leukemia cells (U937).
    Wang S, Guo CY, Castillo A, Dent P, Grant S.
    Biochem Pharmacol; 1998 Sep 01; 56(5):635-44. PubMed ID: 9783732
    [Abstract] [Full Text] [Related]

  • 7. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis.
    Grant S, Turner AJ, Freemerman AJ, Wang Z, Kramer L, Jarvis WD.
    Exp Cell Res; 1996 Oct 10; 228(1):65-75. PubMed ID: 8892972
    [Abstract] [Full Text] [Related]

  • 8. Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Grant S, Jarvis WD, Swerdlow PS, Turner AJ, Traylor RS, Wallace HJ, Lin PS, Pettit GR, Gewirtz DA.
    Cancer Res; 1992 Nov 15; 52(22):6270-8. PubMed ID: 1423273
    [Abstract] [Full Text] [Related]

  • 9. Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL.
    Wang S, Wang Z, Boise LH, Dent P, Grant S.
    Leukemia; 1999 Oct 15; 13(10):1564-73. PubMed ID: 10516758
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.
    Vrana JA, Kramer LB, Saunders AM, Zhang XF, Dent P, Povirk LF, Grant S.
    Biochem Pharmacol; 1999 Jul 01; 58(1):121-31. PubMed ID: 10403525
    [Abstract] [Full Text] [Related]

  • 11. Chronic exposure to bryostatin-1 increases the radiosensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism.
    Cartee L, Davis C, Lin PS, Grant S.
    Int J Radiat Biol; 2000 Oct 01; 76(10):1323-33. PubMed ID: 11057740
    [Abstract] [Full Text] [Related]

  • 12. Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
    Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S.
    Mol Pharmacol; 1997 Dec 01; 52(6):1000-9. PubMed ID: 9396780
    [Abstract] [Full Text] [Related]

  • 13. Bryostatin 1 increases 1-beta-D-arabinofuranosylcytosine-induced cytochrome c release and apoptosis in human leukemia cells ectopically expressing Bcl-x(L).
    Wang Z, Wang S, Dai Y, Grant S.
    J Pharmacol Exp Ther; 2002 May 01; 301(2):568-77. PubMed ID: 11961058
    [Abstract] [Full Text] [Related]

  • 14. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells.
    Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S.
    Biochem Pharmacol; 1994 Mar 02; 47(5):839-52. PubMed ID: 8135859
    [Abstract] [Full Text] [Related]

  • 15. In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
    Grant S, Boise L, Westin E, Howe C, Pettit GR, Turner A, McCrady C.
    Biochem Pharmacol; 1991 Jul 25; 42(4):853-67. PubMed ID: 1867641
    [Abstract] [Full Text] [Related]

  • 16. Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
    Chelliah J, Freemerman AJ, Wu-Pong S, Jarvis WD, Grant S.
    Biochem Pharmacol; 1997 Sep 01; 54(5):563-73. PubMed ID: 9337072
    [Abstract] [Full Text] [Related]

  • 17. Evidence of a functional role for the cyclin-dependent kinase-inhibitor p21WAF1/CIP1/MDA6 in promoting differentiation and preventing mitochondrial dysfunction and apoptosis induced by sodium butyrate in human myelomonocytic leukemia cells (U937).
    Rosato RR, Wang Z, Gopalkrishnan RV, Fisher PB, Grant S.
    Int J Oncol; 2001 Jul 01; 19(1):181-91. PubMed ID: 11408941
    [Abstract] [Full Text] [Related]

  • 18. Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
    Cartee L, Maggio SC, Smith R, Sankala HM, Dent P, Grant S.
    Mol Cancer Ther; 2003 Jan 01; 2(1):83-93. PubMed ID: 12533676
    [Abstract] [Full Text] [Related]

  • 19. Evidence of a functional role for the cyclin-dependent kinase inhibitor p21CIP1 in leukemic cell (U937) differentiation induced by low concentrations of 1-beta-D-arabinofuranosylcytosine.
    Wang Z, Wang S, Fisher PB, Dent P, Grant S.
    Differentiation; 2000 Aug 01; 66(1):1-13. PubMed ID: 10997587
    [Abstract] [Full Text] [Related]

  • 20. Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms.
    Wang S, Wang Z, Grant S.
    Mol Pharmacol; 2003 Jan 01; 63(1):232-42. PubMed ID: 12488556
    [Abstract] [Full Text] [Related]

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