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329 related items for PubMed ID: 10402467

  • 1. Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.
    Nguyen DH, Catling AD, Webb DJ, Sankovic M, Walker LA, Somlyo AV, Weber MJ, Gonias SL.
    J Cell Biol; 1999 Jul 12; 146(1):149-64. PubMed ID: 10402467
    [Abstract] [Full Text] [Related]

  • 2. Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion.
    Webb DJ, Nguyen DH, Gonias SL.
    J Cell Sci; 2000 Jan 12; 113 ( Pt 1)():123-34. PubMed ID: 10591631
    [Abstract] [Full Text] [Related]

  • 3. Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration.
    Jo M, Thomas KS, Somlyo AV, Somlyo AP, Gonias SL.
    J Biol Chem; 2002 Apr 05; 277(14):12479-85. PubMed ID: 11805108
    [Abstract] [Full Text] [Related]

  • 4. Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc complex is associated with the transient phosphorylation of ERK in urokinase-treated cells.
    Nguyen DH, Webb DJ, Catling AD, Song Q, Dhakephalkar A, Weber MJ, Ravichandran KS, Gonias SL.
    J Biol Chem; 2000 Jun 23; 275(25):19382-8. PubMed ID: 10777511
    [Abstract] [Full Text] [Related]

  • 5. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility.
    Nguyen DH, Hussaini IM, Gonias SL.
    J Biol Chem; 1998 Apr 03; 273(14):8502-7. PubMed ID: 9525964
    [Abstract] [Full Text] [Related]

  • 6. Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth.
    Webb DJ, Thomas KS, Gonias SL.
    J Cell Biol; 2001 Feb 19; 152(4):741-52. PubMed ID: 11266465
    [Abstract] [Full Text] [Related]

  • 7. Urokinase-induced smooth muscle cell responses require distinct signaling pathways: a role for the epidermal growth factor receptor.
    Nicholl SM, Roztocil E, Davies MG.
    J Vasc Surg; 2005 Apr 19; 41(4):672-81. PubMed ID: 15874933
    [Abstract] [Full Text] [Related]

  • 8. The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells.
    Tang H, Kerins DM, Hao Q, Inagami T, Vaughan DE.
    J Biol Chem; 1998 Jul 17; 273(29):18268-72. PubMed ID: 9660790
    [Abstract] [Full Text] [Related]

  • 9. Interleukin-1alpha enhances the aggressive behavior of pancreatic cancer cells by regulating the alpha6beta1-integrin and urokinase plasminogen activator receptor expression.
    Sawai H, Okada Y, Funahashi H, Matsuo Y, Takahashi H, Takeyama H, Manabe T.
    BMC Cell Biol; 2006 Feb 20; 7():8. PubMed ID: 16504015
    [Abstract] [Full Text] [Related]

  • 10. Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade.
    Lengyel E, Wang H, Gum R, Simon C, Wang Y, Boyd D.
    Oncogene; 1997 May 29; 14(21):2563-73. PubMed ID: 9191056
    [Abstract] [Full Text] [Related]

  • 11. Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration.
    Yebra M, Parry GC, Strömblad S, Mackman N, Rosenberg S, Mueller BM, Cheresh DA.
    J Biol Chem; 1996 Nov 15; 271(46):29393-9. PubMed ID: 8910604
    [Abstract] [Full Text] [Related]

  • 12. Urinary-type plasminogen activator (uPA) expression and uPA receptor localization are regulated by alpha 3beta 1 integrin in oral keratinocytes.
    Ghosh S, Brown R, Jones JC, Ellerbroek SM, Stack MS.
    J Biol Chem; 2000 Aug 04; 275(31):23869-76. PubMed ID: 10791952
    [Abstract] [Full Text] [Related]

  • 13. Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells.
    Ma Z, Webb DJ, Jo M, Gonias SL.
    J Cell Sci; 2001 Sep 04; 114(Pt 18):3387-96. PubMed ID: 11591826
    [Abstract] [Full Text] [Related]

  • 14. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling.
    Aguirre Ghiso JA, Kovalski K, Ossowski L.
    J Cell Biol; 1999 Oct 04; 147(1):89-104. PubMed ID: 10508858
    [Abstract] [Full Text] [Related]

  • 15. An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration.
    Mazzieri R, D'Alessio S, Kenmoe RK, Ossowski L, Blasi F.
    Mol Biol Cell; 2006 Jan 04; 17(1):367-78. PubMed ID: 16267271
    [Abstract] [Full Text] [Related]

  • 16. Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.
    Jo M, Thomas KS, Marozkina N, Amin TJ, Silva CM, Parsons SJ, Gonias SL.
    J Biol Chem; 2005 Apr 29; 280(17):17449-57. PubMed ID: 15728176
    [Abstract] [Full Text] [Related]

  • 17. Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells.
    Han Q, Leng J, Bian D, Mahanivong C, Carpenter KA, Pan ZK, Han J, Huang S.
    J Biol Chem; 2002 Dec 13; 277(50):48379-85. PubMed ID: 12377770
    [Abstract] [Full Text] [Related]

  • 18. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.
    King WG, Mattaliano MD, Chan TO, Tsichlis PN, Brugge JS.
    Mol Cell Biol; 1997 Aug 13; 17(8):4406-18. PubMed ID: 9234699
    [Abstract] [Full Text] [Related]

  • 19. Urokinase receptor-dependent upregulation of smooth muscle cell adhesion to vitronectin by urokinase.
    Chang AW, Kuo A, Barnathan ES, Okada SS.
    Arterioscler Thromb Vasc Biol; 1998 Dec 13; 18(12):1855-60. PubMed ID: 9848876
    [Abstract] [Full Text] [Related]

  • 20. A new class of orthosteric uPAR·uPA small-molecule antagonists are allosteric inhibitors of the uPAR·vitronectin interaction.
    Liu D, Zhou D, Wang B, Knabe WE, Meroueh SO.
    ACS Chem Biol; 2015 Jun 19; 10(6):1521-34. PubMed ID: 25671694
    [Abstract] [Full Text] [Related]

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