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Journal Abstract Search

185 related items for PubMed ID: 10409393

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  • 2. Influence of N-substitution of 7-methoxy-4-(aminomethyl)-coumarin on cytochrome P450 metabolism and selectivity.
    Venhorst J, Onderwater RC, Meerman JH, Commandeur JN, Vermeulen NP.
    Drug Metab Dispos; 2000 Dec; 28(12):1524-32. PubMed ID: 11095593
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  • 7. Metabolism of N-substituted 7-methoxy-4-(aminomethyl) -coumarins by cytochrome P450 2D6 mutants and the indication of additional substrate interaction points.
    Keizers PH, Van Dijk BR, De Graaf C, Van Vugt-Lussenburg BM, Vermeulen NP, Commandeur JN.
    Xenobiotica; 2006 Sep; 36(9):763-71. PubMed ID: 16971342
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  • 8. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
    Teiber JF, Hollenberg PF.
    Carcinogenesis; 2000 Aug; 21(8):1559-66. PubMed ID: 10910959
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  • 10. Evaluation of a novel high-throughput assay for cytochrome P450 2D6 using 7-methoxy-4-(aminomethyl)-coumarin.
    Venhorst J, Onderwater RC, Meerman JH, Vermeulen NP, Commandeur JN.
    Eur J Pharm Sci; 2000 Dec; 12(2):151-8. PubMed ID: 11102743
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  • 11. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ, Smith TJ, Murphy SE, Wang MH, Lee J, Tynes RE, Koch P, Yang CS.
    Arch Biochem Biophys; 1996 Sep 01; 333(1):127-38. PubMed ID: 8806763
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  • 12. Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.
    Hickman D, Wang JP, Wang Y, Unadkat JD.
    Drug Metab Dispos; 1998 Mar 01; 26(3):207-15. PubMed ID: 9492382
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  • 14. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
    Yang TJ, Krausz KW, Sai Y, Gonzalez FJ, Gelboin HV.
    Drug Metab Dispos; 1999 Jan 01; 27(1):102-9. PubMed ID: 9884317
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  • 15. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT, Wu YS, Chang YW, Hsieh HP, Chen WC, Lan SJ, Chen CT, Chao YS, Chang L, Sun HY, Yeh TK.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1042-9. PubMed ID: 17403915
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  • 16. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
    Shou M, Krausz KW, Gonzalez FJ, Gelboin HV.
    Arch Biochem Biophys; 1996 Apr 01; 328(1):201-7. PubMed ID: 8638931
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  • 17. Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites.
    Avent KM, DeVoss JJ, Gillam EM.
    Chem Res Toxicol; 2006 Jul 01; 19(7):914-20. PubMed ID: 16841959
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  • 18. Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.
    Spracklin DK, Hankins DC, Fisher JM, Thummel KE, Kharasch ED.
    J Pharmacol Exp Ther; 1997 Apr 01; 281(1):400-11. PubMed ID: 9103523
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  • 19. Cyp2D6 catalyzes 5-hydroxylation of 1-(2-pyrimidinyl)-piperazine, an active metabolite of several psychoactive drugs, in human liver microsomes.
    Raghavan N, Zhang D, Zhu M, Zeng J, Christopher L.
    Drug Metab Dispos; 2005 Feb 01; 33(2):203-8. PubMed ID: 15507542
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  • 20. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
    Staack RF, Theobald DS, Paul LD, Springer D, Kraemer T, Maurer HH.
    Drug Metab Dispos; 2004 Apr 01; 32(4):379-81. PubMed ID: 15039289
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