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347 related items for PubMed ID: 10409398

  • 1. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
    Taatjes DJ, Fenick DJ, Koch TH.
    Chem Res Toxicol; 1999 Jul; 12(7):588-96. PubMed ID: 10409398
    [Abstract] [Full Text] [Related]

  • 2. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.
    Taatjes DJ, Koch TH.
    Anticancer Res; 1999 Jul; 19(2A):1201-8. PubMed ID: 10368676
    [Abstract] [Full Text] [Related]

  • 3. Doxorubicin-formaldehyde conjugate, doxoform: induction of apoptosis relative to doxorubicin.
    Burke PJ, Koch TH.
    Anticancer Res; 2001 Jul; 21(4A):2753-60. PubMed ID: 11724351
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  • 5. Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
    Fenick DJ, Taatjes DJ, Koch TH.
    J Med Chem; 1997 Aug 01; 40(16):2452-61. PubMed ID: 9258351
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
    Podell ER, Harrington DJ, Taatjes DJ, Koch TH.
    Acta Crystallogr D Biol Crystallogr; 1999 Sep 01; 55(Pt 9):1516-23. PubMed ID: 10489446
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  • 8. Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells.
    Taatjes DJ, Koch TH.
    Curr Med Chem; 2001 Jan 01; 8(1):15-29. PubMed ID: 11172689
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  • 10. Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells.
    Burke PJ, Kalet BT, Koch TH.
    J Med Chem; 2004 Dec 16; 47(26):6509-18. PubMed ID: 15588086
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  • 12. Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (adriamycin)-resistant P388 mouse leukemia cells.
    Ganapathi R, Grabowski D, Rouse W, Riegler F.
    Cancer Res; 1984 Nov 16; 44(11):5056-61. PubMed ID: 6488165
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  • 14. Cross resistance relevance of the chemical structure of different anthracyclines in multidrug resistant cells.
    Tapiero H, Nguyen-Ba G, Lampidis TJ.
    Pathol Biol (Paris); 1994 Apr 16; 42(4):328-37. PubMed ID: 7808786
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  • 15. Cytoplasmic localization of anthracycline antitumor drugs conjugated with reduced glutathione: a possible correlation with multidrug resistance mechanisms.
    Serafino A, Sinibaldi-Vallebona P, Gaudiano G, Koch TH, Rasi G, Garaci E, Ravagnan G.
    Anticancer Res; 1998 Apr 16; 18(2A):1159-66. PubMed ID: 9615782
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  • 17. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.
    Goren D, Horowitz AT, Tzemach D, Tarshish M, Zalipsky S, Gabizon A.
    Clin Cancer Res; 2000 May 16; 6(5):1949-57. PubMed ID: 10815920
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  • 18. Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.
    Burke PJ, Koch TH.
    J Med Chem; 2004 Feb 26; 47(5):1193-206. PubMed ID: 14971899
    [Abstract] [Full Text] [Related]

  • 19. 4'-Epidoxorubicin to re-explore anthracycline degradation in cardiomyocytes.
    Menna P, Salvatorelli E, Minotti G.
    Chem Res Toxicol; 2009 Jun 26; 22(6):978-83. PubMed ID: 19397277
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