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188 related items for PubMed ID: 10413033

  • 1. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.
    Kuroda S, Tsuchidate R, Smith ML, Maples KR, Siesjö BK.
    J Cereb Blood Flow Metab; 1999 Jul; 19(7):778-87. PubMed ID: 10413033
    [Abstract] [Full Text] [Related]

  • 2. Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia.
    Yang Y, Li Q, Shuaib A.
    Exp Neurol; 2000 May; 163(1):39-45. PubMed ID: 10785442
    [Abstract] [Full Text] [Related]

  • 3. NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.
    Han M, He QP, Yong G, Siesjö BK, Li PA.
    Cell Mol Biol (Noisy-le-grand); 2003 Dec; 49(8):1249-52. PubMed ID: 14983994
    [Abstract] [Full Text] [Related]

  • 4. Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window.
    Sydserff SG, Borelli AR, Green AR, Cross AJ.
    Br J Pharmacol; 2002 Jan; 135(1):103-12. PubMed ID: 11786485
    [Abstract] [Full Text] [Related]

  • 5. In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions.
    Dehouck MP, Cecchelli R, Richard Green A, Renftel M, Lundquist S.
    Brain Res; 2002 Nov 15; 955(1-2):229-35. PubMed ID: 12419541
    [Abstract] [Full Text] [Related]

  • 6. Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats.
    Marklund N, Lewander T, Clausen F, Hillered L.
    J Cereb Blood Flow Metab; 2001 Nov 15; 21(11):1259-67. PubMed ID: 11702041
    [Abstract] [Full Text] [Related]

  • 7. Effect of NXY-059 on secondary mitochondrial dysfunction after transient focal ischemia; comparison with cyclosporin A.
    Yoshimoto T, Kristián T, Hu B, Ouyang YB, Siesjö BK.
    Brain Res; 2002 Apr 05; 932(1-2):99-109. PubMed ID: 11911866
    [Abstract] [Full Text] [Related]

  • 8. The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat.
    Nakai A, Kuroda S, Kristián T, Siesjö BK.
    Neurobiol Dis; 1997 Apr 05; 4(3-4):288-300. PubMed ID: 9361306
    [Abstract] [Full Text] [Related]

  • 9. NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.
    Zhao Z, Cheng M, Maples KR, Ma JY, Buchan AM.
    Brain Res; 2001 Aug 03; 909(1-2):46-50. PubMed ID: 11478919
    [Abstract] [Full Text] [Related]

  • 10. Comparison of neuroprotective effects induced by alpha-phenyl-N-tert-butyl nitrone (PBN) and N-tert-butyl-alpha-(2 sulfophenyl) nitrone (S-PBN) in lithium-pilocarpine status epilepticus.
    Peterson SL, Purvis RS, Griffith JW.
    Neurotoxicology; 2005 Dec 03; 26(6):969-79. PubMed ID: 15890407
    [Abstract] [Full Text] [Related]

  • 11. Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke.
    Maples KR, Green AR, Floyd RA.
    CNS Drugs; 2004 Dec 03; 18(15):1071-84. PubMed ID: 15581379
    [Abstract] [Full Text] [Related]

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  • 13. Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia.
    Green AR, Lanbeck-Vallén K, Ashwood T, Lundquist S, Lindström Böö E, Jonasson H, Campbell M.
    Brain Res; 2006 Feb 09; 1072(1):224-6. PubMed ID: 16448628
    [Abstract] [Full Text] [Related]

  • 14. Delayed treatment with alpha-phenyl-N-tert-butyl nitrone (PBN) attenuates secondary mitochondrial dysfunction after transient focal cerebral ischemia in the rat.
    Kuroda S, Katsura K, Hillered L, Bates TE, Siesjö BK.
    Neurobiol Dis; 1996 Apr 09; 3(2):149-57. PubMed ID: 9173922
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  • 16. Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia.
    Ginsberg MD, Becker DA, Busto R, Belayev A, Zhang Y, Khoutorova L, Ley JJ, Zhao W, Belayev L.
    Ann Neurol; 2003 Sep 09; 54(3):330-42. PubMed ID: 12953265
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  • 18. Activity of mitochondrial respiratory chain enzymes after transient focal ischemia in the rat.
    Canevari L, Kuroda S, Bates TE, Clark JB, Siesjö BK.
    J Cereb Blood Flow Metab; 1997 Nov 09; 17(11):1166-9. PubMed ID: 9390648
    [Abstract] [Full Text] [Related]

  • 19. Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat.
    Candelario-Jalil E, González-Falcón A, García-Cabrera M, León OS, Fiebich BL.
    Brain Res; 2004 May 08; 1007(1-2):98-108. PubMed ID: 15064140
    [Abstract] [Full Text] [Related]

  • 20. Investigating the free radical trapping ability of NXY-059, S-PBN and PBN.
    Williams HE, Claybourn M, Green AR.
    Free Radic Res; 2007 Sep 08; 41(9):1047-52. PubMed ID: 17729123
    [Abstract] [Full Text] [Related]

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