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Journal Abstract Search


169 related items for PubMed ID: 10413308

  • 1. Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
    Horton JK, Roy G, Piper JT, Van Houten B, Awasthi YC, Mitra S, Alaoui-Jamali MA, Boldogh I, Singhal SS.
    Biochem Pharmacol; 1999 Aug 15; 58(4):693-702. PubMed ID: 10413308
    [Abstract] [Full Text] [Related]

  • 2. Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
    Roy G, Horton JK, Roy R, Denning T, Mitra S, Boldogh I.
    Oncogene; 2000 Jan 06; 19(1):141-50. PubMed ID: 10644989
    [Abstract] [Full Text] [Related]

  • 3. Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
    Geroni C, Marchini S, Cozzi P, Galliera E, Ragg E, Colombo T, Battaglia R, Howard M, D'Incalci M, Broggini M.
    Cancer Res; 2002 Apr 15; 62(8):2332-6. PubMed ID: 11956092
    [Abstract] [Full Text] [Related]

  • 4. Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.
    Boldogh I, Roy G, Lee MS, Bacsi A, Hazra TK, Bhakat KK, Das GC, Mitra S.
    Toxicology; 2003 Nov 15; 193(1-2):137-52. PubMed ID: 14599773
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of chlorambucil by rat liver microsomal glutathione S-transferase.
    Zhang J, Ye Z, Lou Y.
    Chem Biol Interact; 2004 Aug 10; 149(1):61-7. PubMed ID: 15356922
    [Abstract] [Full Text] [Related]

  • 6. Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents.
    Townsend AJ, Tu CP, Cowan KH.
    Mol Pharmacol; 1992 Feb 10; 41(2):230-6. PubMed ID: 1538704
    [Abstract] [Full Text] [Related]

  • 7. Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil.
    Pandya U, Srivastava SK, Singhal SS, Pal A, Awasthi S, Zimniak P, Awasthi YC, Singh SV.
    Biochem Biophys Res Commun; 2000 Nov 11; 278(1):258-62. PubMed ID: 11071881
    [Abstract] [Full Text] [Related]

  • 8. Increased levels of alpha-class and pi-class glutathione S-transferases in cell lines resistant to 1-chloro-2,4-dinitrobenzene.
    Wareing CJ, Black SM, Hayes JD, Wolf CR.
    Eur J Biochem; 1993 Oct 15; 217(2):671-6. PubMed ID: 8223610
    [Abstract] [Full Text] [Related]

  • 9. Role of multidrug resistance protein 1 (MRP1) and glutathione S-transferase A1-1 in alkylating agent resistance. Kinetics of glutathione conjugate formation and efflux govern differential cellular sensitivity to chlorambucil versus melphalan toxicity.
    Paumi CM, Ledford BG, Smitherman PK, Townsend AJ, Morrow CS.
    J Biol Chem; 2001 Mar 16; 276(11):7952-6. PubMed ID: 11115505
    [Abstract] [Full Text] [Related]

  • 10. Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
    Wang W, Liu G, Zheng J.
    Eur J Pharmacol; 2007 Jul 30; 568(1-3):61-7. PubMed ID: 17509556
    [Abstract] [Full Text] [Related]

  • 11. Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.
    Alaoui-Jamali MA, Panasci L, Centurioni GM, Schecter R, Lehnert S, Batist G.
    Cancer Chemother Pharmacol; 1992 Jul 30; 30(5):341-7. PubMed ID: 1505071
    [Abstract] [Full Text] [Related]

  • 12. Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance.
    Wang YY, Teicher BA, Shea TC, Holden SA, Rosbe KW, al-Achi A, Henner WD.
    Cancer Res; 1989 Nov 15; 49(22):6185-92. PubMed ID: 2804968
    [Abstract] [Full Text] [Related]

  • 13. Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity.
    Smitherman PK, Townsend AJ, Kute TE, Morrow CS.
    J Pharmacol Exp Ther; 2004 Jan 15; 308(1):260-7. PubMed ID: 14569069
    [Abstract] [Full Text] [Related]

  • 14. Enhanced gamma-glutamylcysteine synthetase activity decreases drug-induced oxidative stress levels and cytotoxicity.
    Das GC, Bacsi A, Shrivastav M, Hazra TK, Boldogh I.
    Mol Carcinog; 2006 Sep 15; 45(9):635-47. PubMed ID: 16491484
    [Abstract] [Full Text] [Related]

  • 15. Time course of glutathione S-transferase elevation in Walker mammary carcinoma cells following chlorambucil exposure.
    Clapper ML, Kuzmich S, Seestaller LM, Tew KD.
    Biochem Pharmacol; 1993 Feb 09; 45(3):683-90. PubMed ID: 7680202
    [Abstract] [Full Text] [Related]

  • 16. Characteristics of the glutathione/glutathione-S-transferase detoxification system in melphalan resistant human prostate cancer cells.
    Ripple M, Mulcahy RT, Wilding G.
    J Urol; 1993 Jul 09; 150(1):209-14. PubMed ID: 8510259
    [Abstract] [Full Text] [Related]

  • 17. Rapid development of glutathione-S-transferase-dependent drug resistance in vitro and its prevention by ethacrynic acid.
    Caffrey PB, Zhu M, Zhang Y, Chinen N, Frenkel GD.
    Cancer Lett; 1999 Feb 08; 136(1):47-52. PubMed ID: 10211938
    [Abstract] [Full Text] [Related]

  • 18. Role of glutathione and glutathione S-transferase in chlorambucil resistance.
    Yang WZ, Begleiter A, Johnston JB, Israels LG, Mowat MR.
    Mol Pharmacol; 1992 Apr 08; 41(4):625-30. PubMed ID: 1569917
    [Abstract] [Full Text] [Related]

  • 19. Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards.
    Clapper ML, Tew KD.
    Biochem Pharmacol; 1989 Jun 15; 38(12):1915-21. PubMed ID: 2742599
    [Abstract] [Full Text] [Related]

  • 20. Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols.
    Zhang K, Wong KP, Chow P.
    Life Sci; 2003 Apr 25; 72(23):2629-40. PubMed ID: 12672508
    [Abstract] [Full Text] [Related]


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