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192 related items for PubMed ID: 10415848

  • 1. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
    Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB.
    Ann N Y Acad Sci; 1999 Jun 30; 880():31-7. PubMed ID: 10415848
    [Abstract] [Full Text] [Related]

  • 2. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ.
    Cancer Res; 1997 Sep 15; 57(18):3929-34. PubMed ID: 9307274
    [Abstract] [Full Text] [Related]

  • 3. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.
    Clin Cancer Res; 2002 Nov 15; 8(11):3628-38. PubMed ID: 12429655
    [Abstract] [Full Text] [Related]

  • 4. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
    Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ.
    Cancer Res; 1998 Dec 15; 58(24):5656-61. PubMed ID: 9865717
    [Abstract] [Full Text] [Related]

  • 5. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.
    Chen WB, Lenschow W, Tiede K, Fischer JW, Kalthoff H, Ungefroren H.
    J Biol Chem; 2002 Sep 27; 277(39):36118-28. PubMed ID: 12140283
    [Abstract] [Full Text] [Related]

  • 6. High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells.
    Sohn TA, Su GH, Ryu B, Yeo CJ, Kern SE.
    Ann Surg; 2001 May 27; 233(5):696-703. PubMed ID: 11323508
    [Abstract] [Full Text] [Related]

  • 7. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
    Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.
    Oncogene; 2004 Feb 05; 23(5):1043-51. PubMed ID: 14762439
    [Abstract] [Full Text] [Related]

  • 8. Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis.
    Schwarte-Waldhoff I, Volpert OV, Bouck NP, Sipos B, Hahn SA, Klein-Scory S, Lüttges J, Klöppel G, Graeven U, Eilert-Micus C, Hintelmann A, Schmiegel W.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9624-9. PubMed ID: 10944227
    [Abstract] [Full Text] [Related]

  • 9. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP, Roelen BA, ten Dijke P, van der Burg B, van den Eijnden-van Raaij AJ.
    Oncogene; 1997 Apr 24; 14(16):1891-9. PubMed ID: 9150356
    [Abstract] [Full Text] [Related]

  • 10. Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma.
    Venkatasubbarao K, Ahmed MM, Mohiuddin M, Swiderski C, Lee E, Gower WR, Salhab KF, McGrath P, Strodel W, Freeman JW.
    Anticancer Res; 2000 Apr 24; 20(1A):43-51. PubMed ID: 10769633
    [Abstract] [Full Text] [Related]

  • 11. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT, Bartlett C, Henry E, Weissman BE.
    J Cell Physiol; 2003 Mar 24; 194(3):289-302. PubMed ID: 12548549
    [Abstract] [Full Text] [Related]

  • 12. Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia.
    Biankin AV, Kench JG, Morey AL, Lee CS, Biankin SA, Head DR, Hugh TB, Henshall SM, Sutherland RL.
    Cancer Res; 2001 Dec 15; 61(24):8830-7. PubMed ID: 11751405
    [Abstract] [Full Text] [Related]

  • 13. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
    Jonckheere N, Perrais M, Mariette C, Batra SK, Aubert JP, Pigny P, Van Seuningen I.
    Oncogene; 2004 Jul 29; 23(34):5729-38. PubMed ID: 15184872
    [Abstract] [Full Text] [Related]

  • 14. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
    Jazag A, Ijichi H, Kanai F, Imamura T, Guleng B, Ohta M, Imamura J, Tanaka Y, Tateishi K, Ikenoue T, Kawakami T, Arakawa Y, Miyagishi M, Taira K, Kawabe T, Omata M.
    Oncogene; 2005 Jan 20; 24(4):662-71. PubMed ID: 15592526
    [Abstract] [Full Text] [Related]

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  • 16. DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression.
    Schwarte-Waldhoff I, Klein S, Blass-Kampmann S, Hintelmann A, Eilert C, Dreschers S, Kalthoff H, Hahn SA, Schmiegel W.
    Oncogene; 1999 May 20; 18(20):3152-8. PubMed ID: 10340387
    [Abstract] [Full Text] [Related]

  • 17. DPC4/SMAD4 gene alterations in human cancer, and their functional implications.
    Schutte M.
    Ann Oncol; 1999 May 20; 10 Suppl 4():56-9. PubMed ID: 10436786
    [Abstract] [Full Text] [Related]

  • 18. DPC4/Smad4 expression and outcome in pancreatic ductal adenocarcinoma.
    Biankin AV, Morey AL, Lee CS, Kench JG, Biankin SA, Hook HC, Head DR, Hugh TB, Sutherland RL, Henshall SM.
    J Clin Oncol; 2002 Dec 01; 20(23):4531-42. PubMed ID: 12454109
    [Abstract] [Full Text] [Related]

  • 19. Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.
    Liu F, Pouponnot C, Massagué J.
    Genes Dev; 1997 Dec 01; 11(23):3157-67. PubMed ID: 9389648
    [Abstract] [Full Text] [Related]

  • 20. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
    Levy L, Hill CS.
    Mol Cell Biol; 2005 Sep 01; 25(18):8108-25. PubMed ID: 16135802
    [Abstract] [Full Text] [Related]

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