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190 related items for PubMed ID: 10415848

  • 1. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
    Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB.
    Ann N Y Acad Sci; 1999 Jun 30; 880():31-7. PubMed ID: 10415848
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  • 2. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ.
    Cancer Res; 1997 Sep 15; 57(18):3929-34. PubMed ID: 9307274
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  • 3. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.
    Clin Cancer Res; 2002 Nov 15; 8(11):3628-38. PubMed ID: 12429655
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  • 5. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.
    Chen WB, Lenschow W, Tiede K, Fischer JW, Kalthoff H, Ungefroren H.
    J Biol Chem; 2002 Sep 27; 277(39):36118-28. PubMed ID: 12140283
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  • 6. High-throughput drug screening of the DPC4 tumor-suppressor pathway in human pancreatic cancer cells.
    Sohn TA, Su GH, Ryu B, Yeo CJ, Kern SE.
    Ann Surg; 2001 May 27; 233(5):696-703. PubMed ID: 11323508
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  • 7. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
    Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.
    Oncogene; 2004 Feb 05; 23(5):1043-51. PubMed ID: 14762439
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  • 8. Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis.
    Schwarte-Waldhoff I, Volpert OV, Bouck NP, Sipos B, Hahn SA, Klein-Scory S, Lüttges J, Klöppel G, Graeven U, Eilert-Micus C, Hintelmann A, Schmiegel W.
    Proc Natl Acad Sci U S A; 2000 Aug 15; 97(17):9624-9. PubMed ID: 10944227
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  • 9. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP, Roelen BA, ten Dijke P, van der Burg B, van den Eijnden-van Raaij AJ.
    Oncogene; 1997 Apr 24; 14(16):1891-9. PubMed ID: 9150356
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  • 11. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT, Bartlett C, Henry E, Weissman BE.
    J Cell Physiol; 2003 Mar 24; 194(3):289-302. PubMed ID: 12548549
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  • 13. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
    Jonckheere N, Perrais M, Mariette C, Batra SK, Aubert JP, Pigny P, Van Seuningen I.
    Oncogene; 2004 Jul 29; 23(34):5729-38. PubMed ID: 15184872
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  • 15. Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
    Duda DG, Sunamura M, Lefter LP, Furukawa T, Yokoyama T, Yatsuoka T, Abe T, Inoue H, Motoi F, Egawa S, Matsuno S, Horii A.
    Oncogene; 2003 Oct 09; 22(44):6857-64. PubMed ID: 14534532
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  • 18. DPC4/Smad4 expression and outcome in pancreatic ductal adenocarcinoma.
    Biankin AV, Morey AL, Lee CS, Kench JG, Biankin SA, Hook HC, Head DR, Hugh TB, Sutherland RL, Henshall SM.
    J Clin Oncol; 2002 Dec 01; 20(23):4531-42. PubMed ID: 12454109
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  • 19. Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.
    Liu F, Pouponnot C, Massagué J.
    Genes Dev; 1997 Dec 01; 11(23):3157-67. PubMed ID: 9389648
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  • 20. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
    Levy L, Hill CS.
    Mol Cell Biol; 2005 Sep 01; 25(18):8108-25. PubMed ID: 16135802
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