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187 related items for PubMed ID: 10421546

  • 1. Paclitaxel sensitivity correlates with p53 status and DNA fragmentation, but not G2/M accumulation.
    Rakovitch E, Mellado W, Hall EJ, Pandita TK, Sawant S, Geard CR.
    Int J Radiat Oncol Biol Phys; 1999 Jul 15; 44(5):1119-24. PubMed ID: 10421546
    [Abstract] [Full Text] [Related]

  • 2. Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment.
    Fan S, Cherney B, Reinhold W, Rucker K, O'Connor PM.
    Clin Cancer Res; 1998 Apr 15; 4(4):1047-54. PubMed ID: 9563901
    [Abstract] [Full Text] [Related]

  • 3. Penclomedine-induced DNA fragmentation and p53 accumulation correlate with reproductive cell death in colorectal carcinoma cells with altered p53 status.
    Rakovitch E, Mellado W, Hall EJ, Sawant SG, Geard CR, Newman RA, Pandita TK.
    Oncol Rep; 1999 Apr 15; 6(1):161-5. PubMed ID: 9864421
    [Abstract] [Full Text] [Related]

  • 4. Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation.
    DeWeese TL, Walsh JC, Dillehay LE, Kessis TD, Hedrick L, Cho KR, Nelson WG.
    Int J Radiat Oncol Biol Phys; 1997 Jan 01; 37(1):145-54. PubMed ID: 9054890
    [Abstract] [Full Text] [Related]

  • 5. Taxol-induced cell cycle arrest and apoptosis: dose-response relationship in lung cancer cells of different wild-type p53 status and under isogenic condition.
    Das GC, Holiday D, Gallardo R, Haas C.
    Cancer Lett; 2001 Apr 26; 165(2):147-53. PubMed ID: 11275363
    [Abstract] [Full Text] [Related]

  • 6. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P, Robey R, Fojo T, Blagosklonny MV.
    Oncogene; 2001 Jun 28; 20(29):3806-13. PubMed ID: 11439344
    [Abstract] [Full Text] [Related]

  • 7. UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.
    Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM.
    J Natl Cancer Inst; 1996 Jul 17; 88(14):956-65. PubMed ID: 8667426
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis as a measure of chemosensitivity to cisplatin and taxol therapy in ovarian cancer cell lines.
    Gibb RK, Taylor DD, Wan T, O'Connor DM, Doering DL, Gerçel-Taylor C.
    Gynecol Oncol; 1997 Apr 17; 65(1):13-22. PubMed ID: 9103385
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis induced by low-dose paclitaxel is associated with p53 upregulation in nasopharyngeal carcinoma cells.
    Tan G, Heqing L, Jiangbo C, Ming J, Yanhong M, Xianghe L, Hong S, Li G.
    Int J Cancer; 2002 Jan 10; 97(2):168-72. PubMed ID: 11774260
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
    Menendez JA, Vellon L, Colomer R, Lupu R.
    Int J Cancer; 2005 May 20; 115(1):19-35. PubMed ID: 15657900
    [Abstract] [Full Text] [Related]

  • 11. A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes.
    Cassinelli G, Supino R, Perego P, Polizzi D, Lanzi C, Pratesi G, Zunino F.
    Int J Cancer; 2001 Jun 01; 92(5):738-47. PubMed ID: 11340581
    [Abstract] [Full Text] [Related]

  • 12. Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway.
    Woods CM, Zhu J, McQueney PA, Bollag D, Lazarides E.
    Mol Med; 1995 Jul 01; 1(5):506-26. PubMed ID: 8529117
    [Abstract] [Full Text] [Related]

  • 13. Paclitaxel/Taxol sensitivity in human renal cell carcinoma is not determined by the p53 status.
    Reinecke P, Kalinski T, Mahotka C, Schmitz M, Déjosez M, Gabbert HE, Gerharz CD.
    Cancer Lett; 2005 May 26; 222(2):165-71. PubMed ID: 15863265
    [Abstract] [Full Text] [Related]

  • 14. Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors.
    McDonald AC, Brown R.
    Br J Cancer; 1998 Sep 26; 78(6):745-51. PubMed ID: 9743293
    [Abstract] [Full Text] [Related]

  • 15. Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitors toward human carcinoma cells with different p53 status.
    Bozko P, Larsen AK, Raymond E, Skladanowski A.
    Acta Biochim Pol; 2002 Sep 26; 49(1):109-19. PubMed ID: 12136930
    [Abstract] [Full Text] [Related]

  • 16. DNA damage increases sensitivity to vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4.
    Zhang CC, Yang JM, Bash-Babula J, White E, Murphy M, Levine AJ, Hait WN.
    Cancer Res; 1999 Aug 01; 59(15):3663-70. PubMed ID: 10446979
    [Abstract] [Full Text] [Related]

  • 17. Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis.
    Vikhanskaya F, Vignati S, Beccaglia P, Ottoboni C, Russo P, D'Incalci M, Broggini M.
    Exp Cell Res; 1998 May 25; 241(1):96-101. PubMed ID: 9633517
    [Abstract] [Full Text] [Related]

  • 18. The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells.
    van Bree C, Savonije JH, Franken NA, Haveman J, Bakker PJ.
    Int J Oncol; 2000 Apr 25; 16(4):739-44. PubMed ID: 10717242
    [Abstract] [Full Text] [Related]

  • 19. Sequence-dependent antagonism between fluorouracil and paclitaxel in human breast cancer cells.
    Grem JL, Nguyen D, Monahan BP, Kao V, Geoffroy FJ.
    Biochem Pharmacol; 1999 Aug 01; 58(3):477-86. PubMed ID: 10424768
    [Abstract] [Full Text] [Related]

  • 20. Relationship of mitotic arrest and apoptosis to antitumor effect of paclitaxel.
    Milross CG, Mason KA, Hunter NR, Chung WK, Peters LJ, Milas L.
    J Natl Cancer Inst; 1996 Sep 18; 88(18):1308-14. PubMed ID: 8797771
    [Abstract] [Full Text] [Related]

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