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Journal Abstract Search

150 related items for PubMed ID: 10421611

  • 1. Involvement of CYP2E1 as A low-affinity enzyme in phenacetin O-deethylation in human liver microsomes.
    Kobayashi K, Nakajima M, Oshima K, Shimada N, Yokoi T, Chiba K.
    Drug Metab Dispos; 1999 Aug; 27(8):860-5. PubMed ID: 10421611
    [Abstract] [Full Text] [Related]

  • 2. Activation of phenacetin O-deethylase activity by alpha-naphthoflavone in human liver microsomes.
    Nakajima M, Kobayashi K, Oshima K, Shimada N, Tokudome S, Chiba K, Yokoi T.
    Xenobiotica; 1999 Sep; 29(9):885-98. PubMed ID: 10548449
    [Abstract] [Full Text] [Related]

  • 3. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M, Nakamura S, Tokudome S, Shimada N, Yamazaki H, Yokoi T.
    Drug Metab Dispos; 1999 Dec; 27(12):1381-91. PubMed ID: 10570018
    [Abstract] [Full Text] [Related]

  • 4. Human cytochromes P450 mediating phenacetin O-deethylation in vitro: validation of the high affinity component as an index of CYP1A2 activity.
    Venkatakrishnan K, von Moltke LL, Greenblatt DJ.
    J Pharm Sci; 1998 Dec; 87(12):1502-7. PubMed ID: 10189256
    [Abstract] [Full Text] [Related]

  • 5. Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.
    Tassaneeyakul W, Birkett DJ, Veronese ME, McManus ME, Tukey RH, Quattrochi LC, Gelboin HV, Miners JO.
    J Pharmacol Exp Ther; 1993 Apr; 265(1):401-7. PubMed ID: 8474022
    [Abstract] [Full Text] [Related]

  • 6. Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1.
    Ozawa S, Ohta K, Miyajima A, Kurebayashi H, Sunouchi M, Shimizu M, Murayama N, Matsumoto Y, Fukuoka M, Ohno Y.
    Xenobiotica; 2000 Oct; 30(10):1005-17. PubMed ID: 11315102
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
    Murray S, Odupitan AO, Murray BP, Boobis AR, Edwards RJ.
    Xenobiotica; 2001 Mar; 31(3):135-51. PubMed ID: 11465391
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2.
    Haritos VS, Ching MS, Ghabrial H, Gross AS, Taavitsainen P, Pelkonen O, Battaglia SE, Smallwood RA, Ahokas JT.
    Pharmacogenetics; 1998 Oct; 8(5):423-32. PubMed ID: 9825834
    [Abstract] [Full Text] [Related]

  • 9. Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4.
    Salmela KS, Tsyrlov IB, Lieber CS.
    Alcohol Clin Exp Res; 2001 Feb; 25(2):253-60. PubMed ID: 11236840
    [Abstract] [Full Text] [Related]

  • 10. Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.
    Eagling VA, Tjia JF, Back DJ.
    Br J Clin Pharmacol; 1998 Feb; 45(2):107-14. PubMed ID: 9491822
    [Abstract] [Full Text] [Related]

  • 11. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    Wen X, Wang JS, Neuvonen PJ, Backman JT.
    Eur J Clin Pharmacol; 2002 Jan; 57(11):799-804. PubMed ID: 11868802
    [Abstract] [Full Text] [Related]

  • 12. Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine.
    von Moltke LL, Greenblatt DJ, Duan SX, Schmider J, Kudchadker L, Fogelman SM, Harmatz JS, Shader RI.
    Psychopharmacology (Berl); 1996 Dec; 128(4):398-407. PubMed ID: 8986010
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 14. Identification of human cytochrome P450 isoforms involved in the 7-hydroxylation of chlorpromazine by human liver microsomes.
    Yoshii K, Kobayashi K, Tsumuji M, Tani M, Shimada N, Chiba K.
    Life Sci; 2000 Oct; 67(2):175-84. PubMed ID: 10901285
    [Abstract] [Full Text] [Related]

  • 15. Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    Ball SE, Ahern D, Scatina J, Kao J.
    Br J Clin Pharmacol; 1997 Jun; 43(6):619-26. PubMed ID: 9205822
    [Abstract] [Full Text] [Related]

  • 16. [O-ethyl 14C]phenacetin O-deethylase activity in human liver microsomes.
    Rodrigues AD, Surber BW, Yao Y, Wong SL, Roberts EM.
    Drug Metab Dispos; 1997 Sep; 25(9):1097-100. PubMed ID: 9311627
    [Abstract] [Full Text] [Related]

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  • 19. Fluvoxamine is a potent inhibitor of cytochrome P4501A2.
    Brøsen K, Skjelbo E, Rasmussen BB, Poulsen HE, Loft S.
    Biochem Pharmacol; 1993 Mar 24; 45(6):1211-4. PubMed ID: 8466541
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