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111 related items for PubMed ID: 10423250

  • 1. Receptor activation by human C5a des Arg74 but not intact C5a is dependent on an interaction between Glu199 of the receptor and Lys68 of the ligand.
    Crass T, Bautsch W, Cain SA, Pease JE, Monk PN.
    Biochemistry; 1999 Jul 27; 38(30):9712-7. PubMed ID: 10423250
    [Abstract] [Full Text] [Related]

  • 2. Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminus.
    Monk PN, Barker MD, Partridge LJ, Pease JE.
    J Biol Chem; 1995 Jul 14; 270(28):16625-9. PubMed ID: 7622471
    [Abstract] [Full Text] [Related]

  • 3. The C terminus of the human C5a receptor (CD88) is required for normal ligand-dependent receptor internalization.
    Bock D, Martin U, Gärtner S, Rheinheimer C, Raffetseder U, Arseniev L, Barker MD, Monk PN, Bautsch W, Köhl J, Klos A.
    Eur J Immunol; 1997 Jun 14; 27(6):1522-9. PubMed ID: 9209506
    [Abstract] [Full Text] [Related]

  • 4. Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.
    Cain SA, Coughlan T, Monk PN.
    Biochemistry; 2001 Nov 20; 40(46):14047-52. PubMed ID: 11705397
    [Abstract] [Full Text] [Related]

  • 5. Direct binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.
    Tardif M, Brouchon L, Rabiet MJ, Boulay F.
    Biochem J; 2003 Jun 01; 372(Pt 2):453-63. PubMed ID: 12600272
    [Abstract] [Full Text] [Related]

  • 6. The influence of Lys68 in decepeptide agonists of C5a on C5a receptor binding, activation and selectivity.
    Vogen SM, Finch AM, Wadi SK, Thatcher J, Monk PN, Taylor SM, Sanderson SD.
    J Pept Res; 1999 Jan 01; 53(1):8-17. PubMed ID: 10195437
    [Abstract] [Full Text] [Related]

  • 7. Mutation of aspartate 82 of the human C5a receptor abolishes the secretory response to human C5a in transfected rat basophilic leukemia cells.
    Monk PN, Pease JE, Marland G, Barker MD.
    Eur J Immunol; 1994 Nov 01; 24(11):2922-5. PubMed ID: 7957584
    [Abstract] [Full Text] [Related]

  • 8. Selection of a C5a receptor antagonist from phage libraries attenuating the inflammatory response in immune complex disease and ischemia/reperfusion injury.
    Heller T, Hennecke M, Baumann U, Gessner JE, zu Vilsendorf AM, Baensch M, Boulay F, Kola A, Klos A, Bautsch W, Köhl J.
    J Immunol; 1999 Jul 15; 163(2):985-94. PubMed ID: 10395696
    [Abstract] [Full Text] [Related]

  • 9. Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors.
    Oppermann M, Götze O.
    Immunology; 1994 Aug 15; 82(4):516-21. PubMed ID: 7835913
    [Abstract] [Full Text] [Related]

  • 10. The chemoattractant des-Arg74-C5a regulates the expression of its own receptor on a monocyte-like cell line.
    Barker MD, Jose PJ, Williams TJ, Burton DR.
    Biochem J; 1986 Jun 01; 236(2):621-4. PubMed ID: 3019322
    [Abstract] [Full Text] [Related]

  • 11. Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor.
    Bubeck P, Grötzinger J, Winkler M, Köhl J, Wollmer A, Klos A, Bautsch W.
    Eur J Biochem; 1994 Feb 01; 219(3):897-904. PubMed ID: 8112341
    [Abstract] [Full Text] [Related]

  • 12. Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells.
    Kola A, Baensch M, Bautsch W, Klos A, Köhl J.
    Mol Immunol; 1999 Feb 01; 36(2):145-52. PubMed ID: 10378686
    [Abstract] [Full Text] [Related]

  • 13. The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding.
    Scola AM, Higginbottom A, Partridge LJ, Reid RC, Woodruff T, Taylor SM, Fairlie DP, Monk PN.
    J Biol Chem; 2007 Feb 09; 282(6):3664-71. PubMed ID: 17158873
    [Abstract] [Full Text] [Related]

  • 14. Solution structure of a unique C5a semi-synthetic antagonist: implications in receptor binding.
    Zhang X, Boyar W, Galakatos N, Gonnella NC.
    Protein Sci; 1997 Jan 09; 6(1):65-72. PubMed ID: 9007977
    [Abstract] [Full Text] [Related]

  • 15. Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a.
    Wong AK, Finch AM, Pierens GK, Craik DJ, Taylor SM, Fairlie DP.
    J Med Chem; 1998 Aug 27; 41(18):3417-25. PubMed ID: 9719594
    [Abstract] [Full Text] [Related]

  • 16. Characterisation of C5a receptor agonists from phage display libraries.
    Cain SA, Higginbottom A, Monk PN.
    Biochem Pharmacol; 2003 Nov 01; 66(9):1833-40. PubMed ID: 14563493
    [Abstract] [Full Text] [Related]

  • 17. Differential expression of the C5a receptor on the main cell types of rat liver as demonstrated with a novel monoclonal antibody and by C5a anaphylatoxin-induced Ca2+ release.
    Schlaf G, Schieferdecker HL, Rothermel E, Jungermann K, Götze O.
    Lab Invest; 1999 Oct 01; 79(10):1287-97. PubMed ID: 10532591
    [Abstract] [Full Text] [Related]

  • 18. Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor.
    Cain SA, Woodruff TM, Taylor SM, Fairlie DP, Sanderson SD, Monk PN.
    Biochem Pharmacol; 2001 Jun 15; 61(12):1571-9. PubMed ID: 11377387
    [Abstract] [Full Text] [Related]

  • 19. Differential regulation of the C3a and C5a receptors (CD88) by IFN-gamma and PMA in U937 cells and related myeloblastic cell lines.
    Burg M, Martin U, Bock D, Rheinheimer C, Köhl J, Bautsch W, Klos A.
    J Immunol; 1996 Dec 15; 157(12):5574-81. PubMed ID: 8955209
    [Abstract] [Full Text] [Related]

  • 20. C5L2, a nonsignaling C5A binding protein.
    Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C.
    Biochemistry; 2003 Aug 12; 42(31):9406-15. PubMed ID: 12899627
    [Abstract] [Full Text] [Related]

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