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Journal Abstract Search

364 related items for PubMed ID: 10425105

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  • 5. Design, synthesis, and biological activity of prazosin-related antagonists. Role of the piperazine and furan units of prazosin on the selectivity for alpha1-adrenoreceptor subtypes.
    Bolognesi ML, Budriesi R, Chiarini A, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 1998 Nov 19; 41(24):4844-53. PubMed ID: 9822553
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  • 6. 1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists.
    Brasili L, Sorbi C, Franchini S, Manicardi M, Angeli P, Marucci G, Leonardi A, Poggesi E.
    J Med Chem; 2003 Apr 10; 46(8):1504-11. PubMed ID: 12672251
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  • 7. New potential uroselective NO-donor alpha1-antagonists.
    Boschi D, Tron GC, Di Stilo A, Fruttero R, Gasco A, Poggesi E, Motta G, Leonardi A.
    J Med Chem; 2003 Aug 14; 46(17):3762-5. PubMed ID: 12904082
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  • 8. Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist.
    Quaglia W, Pigini M, Tayebati SK, Piergentili A, Giannella M, Leonardi A, Taddei C, Melchiorre C.
    J Med Chem; 1996 May 24; 39(11):2253-8. PubMed ID: 8667368
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  • 9. Structure-activity relationships in 1,4-benzodioxan-related compounds. 5. Effects of modification of the side chain on alpha-adrenoreceptor blocking activity.
    Quaglia W, Giannella M, Marucci G, Piergentili A, Pigini M, Tayebati SK, Melchiorre C.
    Farmaco; 1996 Jan 24; 51(1):27-32. PubMed ID: 8721758
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  • 11. Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
    Prandi A, Franchini S, Manasieva LI, Fossa P, Cichero E, Marucci G, Buccioni M, Cilia A, Pirona L, Brasili L.
    J Med Chem; 2012 Jan 12; 55(1):23-36. PubMed ID: 22145629
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  • 12. Alpha1-adrenoceptor antagonists. 6. Structural optimization of pyridazinone-arylpiperazines. Study of the influence on affinity and selectivity of cyclic substituents at the pyridazinone ring and alkoxy groups at the arylpiperazine moiety.
    Betti L, Corelli F, Floridi M, Giannaccini G, Maccari L, Manetti F, Strappaghetti G, Botta M.
    J Med Chem; 2003 Jul 31; 46(16):3555-8. PubMed ID: 12877594
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  • 13. Structure-affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of alpha 1 antagonist WB-4101.
    Bolchi C, Catalano P, Fumagalli L, Gobbi M, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E.
    Bioorg Med Chem; 2004 Sep 15; 12(18):4937-51. PubMed ID: 15336273
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  • 14. Failure of AH11110A to functionally discriminate between alpha(1)-adrenoceptor subtypes A, B and D or between alpha(1)- and alpha(2)-adrenoceptors.
    Eltze M, König H, Ullrich B, Grebe T.
    Eur J Pharmacol; 2001 Mar 15; 415(2-3):265-76. PubMed ID: 11275009
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  • 15. Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.
    Millan MJ, Newman-Tancredi A, Audinot V, Cussac D, Lejeune F, Nicolas JP, Cogé F, Galizzi JP, Boutin JA, Rivet JM, Dekeyne A, Gobert A.
    Synapse; 2000 Feb 15; 35(2):79-95. PubMed ID: 10611634
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  • 16. Novel adrenoceptor antagonists with a tricyclic pyrrolodipyridazine skeleton.
    Barlocco D, Cignarella G, Montesano F, Leonardi A, Mella M, Toma L.
    J Med Chem; 1999 Jan 14; 42(1):173-7. PubMed ID: 9888842
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  • 17. 1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.
    Tait A, Luppi A, Franchini S, Preziosi E, Parenti C, Buccioni M, Marucci G, Leonardi A, Poggesi E, Brasili L.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1185-8. PubMed ID: 15686938
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  • 18. Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists.
    Balle T, Perregaard J, Ramirez MT, Larsen AK, Søby KK, Liljefors T, Andersen K.
    J Med Chem; 2003 Jan 16; 46(2):265-83. PubMed ID: 12519065
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  • 19. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I, Alonso-Cires L, López-Tudanca PL, Mosquera R, Labeaga L, Innerárity A, Orjales A.
    J Med Chem; 1999 Jul 29; 42(15):2870-80. PubMed ID: 10425096
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  • 20. Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
    Zhao MM, Hwa J, Perez DM.
    Mol Pharmacol; 1996 Nov 29; 50(5):1118-26. PubMed ID: 8913343
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