These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

1365 related items for PubMed ID: 10434303

  • 1. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
    Reddy PH, Charles V, Williams M, Miller G, Whetsell WO, Tagle DA.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1035-45. PubMed ID: 10434303
    [Abstract] [Full Text] [Related]

  • 2. Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.
    Reddy PH, Williams M, Charles V, Garrett L, Pike-Buchanan L, Whetsell WO, Miller G, Tagle DA.
    Nat Genet; 1998 Oct 29; 20(2):198-202. PubMed ID: 9771716
    [Abstract] [Full Text] [Related]

  • 3. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
    Wegrzynowicz M, Bichell TJ, Soares BD, Loth MK, McGlothan JS, Mori S, Alikhan FS, Hua K, Coughlin JM, Holt HK, Jetter CS, Pomper MG, Osmand AP, Guilarte TR, Bowman AB.
    J Huntingtons Dis; 2015 Oct 29; 4(1):17-36. PubMed ID: 26333255
    [Abstract] [Full Text] [Related]

  • 4. Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.
    Morton AJ, Glynn D, Leavens W, Zheng Z, Faull RL, Skepper JN, Wight JM.
    Neurobiol Dis; 2009 Mar 29; 33(3):331-41. PubMed ID: 19130884
    [Abstract] [Full Text] [Related]

  • 5. Towards a transgenic model of Huntington's disease in a non-human primate.
    Yang SH, Cheng PH, Banta H, Piotrowska-Nitsche K, Yang JJ, Cheng EC, Snyder B, Larkin K, Liu J, Orkin J, Fang ZH, Smith Y, Bachevalier J, Zola SM, Li SH, Li XJ, Chan AW.
    Nature; 2008 Jun 12; 453(7197):921-4. PubMed ID: 18488016
    [Abstract] [Full Text] [Related]

  • 6. Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin.
    Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM.
    Neurobiol Dis; 2006 Feb 12; 21(2):381-91. PubMed ID: 16150600
    [Abstract] [Full Text] [Related]

  • 7. Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
    Menalled LB, Sison JD, Dragatsis I, Zeitlin S, Chesselet MF.
    J Comp Neurol; 2003 Oct 06; 465(1):11-26. PubMed ID: 12926013
    [Abstract] [Full Text] [Related]

  • 8. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
    Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, Coppola G, Bates GP, Ranum LPW, Horvath S, Colwell CS, Yang XW.
    Neuron; 2022 Apr 06; 110(7):1173-1192.e7. PubMed ID: 35114102
    [Abstract] [Full Text] [Related]

  • 9. Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice.
    Menalled LB, Sison JD, Wu Y, Olivieri M, Li XJ, Li H, Zeitlin S, Chesselet MF.
    J Neurosci; 2002 Sep 15; 22(18):8266-76. PubMed ID: 12223581
    [Abstract] [Full Text] [Related]

  • 10. Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length.
    Becher MW, Kotzuk JA, Sharp AH, Davies SW, Bates GP, Price DL, Ross CA.
    Neurobiol Dis; 1998 Apr 15; 4(6):387-97. PubMed ID: 9666478
    [Abstract] [Full Text] [Related]

  • 11. Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse.
    Cowin RM, Roscic A, Bui N, Graham D, Paganetti P, Jankowsky JL, Weiss A, Paylor R.
    Behav Brain Res; 2012 Apr 15; 229(2):308-19. PubMed ID: 22306231
    [Abstract] [Full Text] [Related]

  • 12. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
    Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, Lawton M, Trottier Y, Lehrach H, Davies SW, Bates GP.
    Cell; 1996 Nov 01; 87(3):493-506. PubMed ID: 8898202
    [Abstract] [Full Text] [Related]

  • 13. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
    Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW.
    J Neurosci; 2008 Jun 11; 28(24):6182-95. PubMed ID: 18550760
    [Abstract] [Full Text] [Related]

  • 14. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H, Li Q, Graham RK, Slow E, Hayden MR, Bezprozvanny I.
    Neurobiol Dis; 2008 Jul 11; 31(1):80-8. PubMed ID: 18502655
    [Abstract] [Full Text] [Related]

  • 15. A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
    Cummings DM, Alaghband Y, Hickey MA, Joshi PR, Hong SC, Zhu C, Ando TK, André VM, Cepeda C, Watson JB, Levine MS.
    J Neurophysiol; 2012 Jan 11; 107(2):677-91. PubMed ID: 22072510
    [Abstract] [Full Text] [Related]

  • 16. Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
    Hansson O, Castilho RF, Korhonen L, Lindholm D, Bates GP, Brundin P.
    J Neurochem; 2001 Aug 11; 78(4):694-703. PubMed ID: 11520890
    [Abstract] [Full Text] [Related]

  • 17. The early cellular pathology of Huntington's disease.
    Li XJ.
    Mol Neurobiol; 1999 Aug 11; 20(2-3):111-24. PubMed ID: 10966117
    [Abstract] [Full Text] [Related]

  • 18. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
    Ho LW, Brown R, Maxwell M, Wyttenbach A, Rubinsztein DC.
    J Med Genet; 2001 Jul 11; 38(7):450-2. PubMed ID: 11432963
    [Abstract] [Full Text] [Related]

  • 19. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E, Gafni J, Propp SS, Leavitt BR, Wellington CL, Young JE, Hackam AS, Logvinova AV, Peel AL, Chen SF, Hook V, Singaraja R, Krajewski S, Goldsmith PC, Ellerby HM, Hayden MR, Bredesen DE, Ellerby LM.
    Cell Death Differ; 2004 Apr 11; 11(4):424-38. PubMed ID: 14713958
    [Abstract] [Full Text] [Related]

  • 20. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
    Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP.
    Cell; 1997 Aug 08; 90(3):537-48. PubMed ID: 9267033
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 69.