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212 related items for PubMed ID: 10441116

  • 1. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1.
    Ji X, Blaszczyk J, Xiao B, O'Donnell R, Hu X, Herzog C, Singh SV, Zimniak P.
    Biochemistry; 1999 Aug 10; 38(32):10231-8. PubMed ID: 10441116
    [Abstract] [Full Text] [Related]

  • 2. Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Hu X, O'Donnell R, Srivastava SK, Xia H, Zimniak P, Nanduri B, Bleicher RJ, Awasthi S, Awasthi YC, Ji X, Singh SV.
    Biochem Biophys Res Commun; 1997 Jun 18; 235(2):424-8. PubMed ID: 9199210
    [Abstract] [Full Text] [Related]

  • 3. Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase.
    Ji X, Tordova M, O'Donnell R, Parsons JF, Hayden JB, Gilliland GL, Zimniak P.
    Biochemistry; 1997 Aug 12; 36(32):9690-702. PubMed ID: 9245401
    [Abstract] [Full Text] [Related]

  • 4. Residue R216 and catalytic efficiency of a murine class alpha glutathione S-transferase toward benzo[a]pyrene 7(R),8(S)-diol 9(S), 10(R)-epoxide.
    Gu Y, Singh SV, Ji X.
    Biochemistry; 2000 Oct 17; 39(41):12552-7. PubMed ID: 11027134
    [Abstract] [Full Text] [Related]

  • 5. Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.
    Gu Y, Xiao B, Wargo HL, Bucher MH, Singh SV, Ji X.
    Biochemistry; 2003 Feb 04; 42(4):917-21. PubMed ID: 12549910
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene.
    Hu X, Ji X, Srivastava SK, Xia H, Awasthi S, Nanduri B, Awasthi YC, Zimniak P, Singh SV.
    Arch Biochem Biophys; 1997 Sep 01; 345(1):32-8. PubMed ID: 9281308
    [Abstract] [Full Text] [Related]

  • 7. Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene.
    Hu X, Xia H, Srivastava SK, Pal A, Awasthi YC, Zimniak P, Singh SV.
    Cancer Res; 1998 Dec 01; 58(23):5340-3. PubMed ID: 9850062
    [Abstract] [Full Text] [Related]

  • 8. Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution.
    Dirr H, Reinemer P, Huber R.
    J Mol Biol; 1994 Oct 14; 243(1):72-92. PubMed ID: 7932743
    [Abstract] [Full Text] [Related]

  • 9. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase.
    Hu X, Herzog C, Zimniak P, Singh SV.
    Cancer Res; 1999 May 15; 59(10):2358-62. PubMed ID: 10344744
    [Abstract] [Full Text] [Related]

  • 10. Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.
    Singh SV, Varma V, Zimniak P, Srivastava SK, Marynowski SW, Desai D, Amin S, Ji X.
    Biochemistry; 2004 Aug 03; 43(30):9708-15. PubMed ID: 15274625
    [Abstract] [Full Text] [Related]

  • 11. Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
    Lo Bello M, Oakley AJ, Battistoni A, Mazzetti AP, Nuccetelli M, Mazzarese G, Rossjohn J, Parker MW, Ricci G.
    Biochemistry; 1997 May 20; 36(20):6207-17. PubMed ID: 9166793
    [Abstract] [Full Text] [Related]

  • 12. Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor.
    Prade L, Huber R, Manoharan TH, Fahl WE, Reuter W.
    Structure; 1997 Oct 15; 5(10):1287-95. PubMed ID: 9351803
    [Abstract] [Full Text] [Related]

  • 13. Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa.
    Srivastava SK, Singhal SS, Hu X, Awasthi YC, Zimniak P, Singh SV.
    Arch Biochem Biophys; 1999 Jun 01; 366(1):89-94. PubMed ID: 10334868
    [Abstract] [Full Text] [Related]

  • 14. Conformational changes in the crystal structure of rat glutathione transferase M1-1 with global substitution of 3-fluorotyrosine for tyrosine.
    Xiao G, Parsons JF, Tesh K, Armstrong RN, Gilliland GL.
    J Mol Biol; 1998 Aug 14; 281(2):323-39. PubMed ID: 9698551
    [Abstract] [Full Text] [Related]

  • 15. The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
    Oakley AJ, Lo Bello M, Nuccetelli M, Mazzetti AP, Parker MW.
    J Mol Biol; 1999 Aug 27; 291(4):913-26. PubMed ID: 10452896
    [Abstract] [Full Text] [Related]

  • 16. Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes.
    Hu X, Pal A, Krzeminski J, Amin S, Awasthi YC, Zimniak P, Singh SV.
    Carcinogenesis; 1998 Sep 27; 19(9):1685-9. PubMed ID: 9771942
    [Abstract] [Full Text] [Related]

  • 17. Cloning, expression, and biochemical characterization of a functionally novel alpha class glutathione S-transferase with exceptional activity in the glutathione conjugation of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
    Xia H, Pan SS, Hu X, Srivastava SK, Pal A, Singh SV.
    Arch Biochem Biophys; 1998 May 15; 353(2):337-48. PubMed ID: 9606968
    [Abstract] [Full Text] [Related]

  • 18. Solution structure of glutathione bound to human glutathione transferase P1-1: comparison of NMR measurements with the crystal structure.
    Nicotra M, Paci M, Sette M, Oakley AJ, Parker MW, Lo Bello M, Caccuri AM, Federici G, Ricci G.
    Biochemistry; 1998 Mar 03; 37(9):3020-7. PubMed ID: 9485454
    [Abstract] [Full Text] [Related]

  • 19. First-sphere and second-sphere electrostatic effects in the active site of a class mu gluthathione transferase.
    Xiao G, Liu S, Ji X, Johnson WW, Chen J, Parsons JF, Stevens WJ, Gilliland GL, Armstrong RN.
    Biochemistry; 1996 Apr 16; 35(15):4753-65. PubMed ID: 8664265
    [Abstract] [Full Text] [Related]

  • 20. Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
    Ji X, Johnson WW, Sesay MA, Dickert L, Prasad SM, Ammon HL, Armstrong RN, Gilliland GL.
    Biochemistry; 1994 Feb 08; 33(5):1043-52. PubMed ID: 8110735
    [Abstract] [Full Text] [Related]

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