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96 related items for PubMed ID: 10443589

  • 1. SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor.
    Middlemiss DN, Göthert M, Schlicker E, Scott CM, Selkirk JV, Watson J, Gaster LM, Wyman P, Riley G, Price GW.
    Eur J Pharmacol; 1999 Jun 30; 375(1-3):359-65. PubMed ID: 10443589
    [Abstract] [Full Text] [Related]

  • 2. SB-236057-A: a selective 5-HT1B receptor inverse agonist.
    Roberts C, Watson J, Price GW, Middlemiss DN.
    CNS Drug Rev; 2001 Jun 30; 7(4):433-44. PubMed ID: 11830759
    [Abstract] [Full Text] [Related]

  • 3. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 1998 Sep 30; 125(1):202-8. PubMed ID: 9776361
    [Abstract] [Full Text] [Related]

  • 4. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
    Scott C, Soffin EM, Hill M, Atkinson PJ, Langmead CJ, Wren PB, Faedo S, Gordon LJ, Price GW, Bromidge S, Johnson CN, Hagan JJ, Watson J.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):54-61. PubMed ID: 16571351
    [Abstract] [Full Text] [Related]

  • 5. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors.
    Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Göthert M.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep 24; 356(3):321-7. PubMed ID: 9303568
    [Abstract] [Full Text] [Related]

  • 6. SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
    Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J.
    Neuropharmacology; 2006 Jun 24; 50(8):984-90. PubMed ID: 16546225
    [Abstract] [Full Text] [Related]

  • 7. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
    [Abstract] [Full Text] [Related]

  • 8. Importance of h5-HT1B receptor selectivity for 5-HT terminal autoreceptor activity: an in vivo microdialysis study in the freely-moving guinea-pig.
    Roberts C, Price GW, Gaster L, Jones BJ, Middlemiss DN, Routledge C.
    Neuropharmacology; 1997 Apr 09; 36(4-5):549-57. PubMed ID: 9225280
    [Abstract] [Full Text] [Related]

  • 9. The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig.
    Roberts C, Hatcher P, Hagan JJ, Austin NE, Jeffrey P, Wyman P, Gaster LM, Routledge C, Middlemiss DN.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Aug 09; 362(2):177-83. PubMed ID: 10961381
    [Abstract] [Full Text] [Related]

  • 10. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.
    Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN.
    Eur J Pharmacol; 2004 Jun 16; 493(1-3):85-93. PubMed ID: 15189767
    [Abstract] [Full Text] [Related]

  • 11. Actions of roxindole at recombinant human dopamine D2, D3 and D4 and serotonin 5-HT1A, 5-HT1B and 5-HT1D receptors.
    Newman-Tancredi A, Cussac D, Audinot V, Millan MJ.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Jun 16; 359(6):447-53. PubMed ID: 10431754
    [Abstract] [Full Text] [Related]

  • 12. Functional characterization of the 5-HT terminal autoreceptor in the guinea-pig brain cortex.
    Roberts C, Watson J, Burton M, Price GW, Jones BJ.
    Br J Pharmacol; 1996 Jan 16; 117(2):384-8. PubMed ID: 8789395
    [Abstract] [Full Text] [Related]

  • 13. SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain.
    Thomas DR, Soffin EM, Roberts C, Kew JN, de la Flor RM, Dawson LA, Fry VA, Coggon SA, Faedo S, Hayes PD, Corbett DF, Davies CH, Hagan JJ.
    Neuropharmacology; 2006 Sep 16; 51(3):566-77. PubMed ID: 16846620
    [Abstract] [Full Text] [Related]

  • 14. Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.
    Hagan JJ, Slade PD, Gaster L, Jeffrey P, Hatcher JP, Middlemiss DN.
    Eur J Pharmacol; 1997 Jul 23; 331(2-3):169-74. PubMed ID: 9274976
    [Abstract] [Full Text] [Related]

  • 15. Functional characterization of 5-HT1D autoreceptors on the modulation of 5-HT release in guinea-pig mesencephalic raphe, hippocampus and frontal cortex.
    el Mansari M, Blier P.
    Br J Pharmacol; 1996 Jun 23; 118(3):681-9. PubMed ID: 8762094
    [Abstract] [Full Text] [Related]

  • 16. The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies.
    Roberts C, Allen L, Langmead CJ, Hagan JJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 2001 Apr 23; 132(7):1574-80. PubMed ID: 11264252
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functions.
    Marcoli M, Maura G, Munari C, Ruelle A, Raiteri M.
    Br J Pharmacol; 1999 Feb 23; 126(3):607-12. PubMed ID: 10188970
    [Abstract] [Full Text] [Related]

  • 18. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors.
    Price GW, Burton MJ, Collin LJ, Duckworth M, Gaster L, Göthert M, Jones BJ, Roberts C, Watson JM, Middlemiss DN.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep 23; 356(3):312-20. PubMed ID: 9303567
    [Abstract] [Full Text] [Related]

  • 19. Pharmacological analysis of G-protein activation mediated by guinea-pig recombinant 5-HT1B receptors in C6-glial cells: similarities with the human 5-HT1B receptor.
    Pauwels PJ, Wurch T, Palmier C, Colpaert FC.
    Br J Pharmacol; 1998 Jan 23; 123(1):51-62. PubMed ID: 9484854
    [Abstract] [Full Text] [Related]

  • 20. (+)-WAY 100135, a partial agonist, at native and recombinant 5-HT1B/1D receptors.
    Davidson C, Ho M, Price GW, Jones BJ, Stamford JA.
    Br J Pharmacol; 1997 Jun 23; 121(4):737-42. PubMed ID: 9208142
    [Abstract] [Full Text] [Related]

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