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78 related items for PubMed ID: 10446399

  • 1. Thrombin mutants with altered enzymatic activity have an impaired mitogenic effect on mouse fibroblasts and are inefficient modulators of stellation of rat cortical astrocytes.
    Arcone R, Pagliuca MG, Chinali A, Grimaldi M, Schettini G, Gast A, Pietropaolo C.
    Biochim Biophys Acta; 1999 Aug 12; 1451(1):173-86. PubMed ID: 10446399
    [Abstract] [Full Text] [Related]

  • 2. Stable expression and purification of a secreted human recombinant prethrombin-2 and its activation to thrombin.
    Russo G, Gast A, Schlaeger EJ, Angiolillo A, Pietropaolo C.
    Protein Expr Purif; 1997 Jul 12; 10(2):214-25. PubMed ID: 9226718
    [Abstract] [Full Text] [Related]

  • 3. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1.
    Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA.
    J Neurochem; 1990 May 12; 54(5):1735-43. PubMed ID: 1691280
    [Abstract] [Full Text] [Related]

  • 4. Pharmacological characterization of protease-activated receptor (PAR-1) in rat astrocytes.
    Debeir T, Vigé X, Benavides J.
    Eur J Pharmacol; 1997 Mar 26; 323(1):111-7. PubMed ID: 9105886
    [Abstract] [Full Text] [Related]

  • 5. Preparation of recombinant alpha-thrombin: high-level expression of recombinant human prethrombin-2 and its activation by recombinant ecarin.
    Yonemura H, Imamura T, Soejima K, Nakahara Y, Morikawa W, Ushio Y, Kamachi Y, Nakatake H, Sugawara K, Nakagaki T, Nozaki C.
    J Biochem; 2004 May 26; 135(5):577-82. PubMed ID: 15173195
    [Abstract] [Full Text] [Related]

  • 6. Single amino acid substitutions dissociate fibrinogen-clotting and thrombomodulin-binding activities of human thrombin.
    Wu QY, Sheehan JP, Tsiang M, Lentz SR, Birktoft JJ, Sadler JE.
    Proc Natl Acad Sci U S A; 1991 Aug 01; 88(15):6775-9. PubMed ID: 1650482
    [Abstract] [Full Text] [Related]

  • 7. A recombinant murine meizothrombin precursor, prothrombin R157A/R268A, inhibits thrombosis in a model of acute carotid artery injury.
    Shim K, Zhu H, Westfield LA, Sadler JE.
    Blood; 2004 Jul 15; 104(2):415-9. PubMed ID: 15039280
    [Abstract] [Full Text] [Related]

  • 8. Intermediates of prothrombin activation induce intracellular calcium mobilization in rat aortic smooth muscle cells.
    Kaufmann R, Hoffmann J, Ramakrishnan V, Nowak G.
    Thromb Haemost; 1998 Dec 15; 80(6):1018-21. PubMed ID: 9869177
    [Abstract] [Full Text] [Related]

  • 9. An efficient refolding method for the preparation of recombinant human prethrombin-2 and characterization of the recombinant-derived alpha-thrombin.
    Soejima K, Mimura N, Yonemura H, Nakatake H, Imamura T, Nozaki C.
    J Biochem; 2001 Aug 15; 130(2):269-77. PubMed ID: 11481045
    [Abstract] [Full Text] [Related]

  • 10. Allosteric modulation of the activity of thrombin.
    Duffy EJ, Angliker H, Le Bonniec BF, Stone SR.
    Biochem J; 1997 Jan 15; 321 ( Pt 2)(Pt 2):361-5. PubMed ID: 9020867
    [Abstract] [Full Text] [Related]

  • 11. Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture.
    Beecher KL, Andersen TT, Fenton JW, Festoff BW.
    J Neurosci Res; 1994 Jan 15; 37(1):108-15. PubMed ID: 8145298
    [Abstract] [Full Text] [Related]

  • 12. Prothrombin cleavage by human vascular smooth muscle cells: a potential alternative pathway to the coagulation cascade.
    Benzakour O, Kanthou C, Lupu F, Dennehy U, Goodwin C, Scully MF, Kakkar VV, Cooper DN.
    J Cell Biochem; 1995 Dec 15; 59(4):514-28. PubMed ID: 8749720
    [Abstract] [Full Text] [Related]

  • 13. Mechanisms of alpha-thrombin and beta-thrombin-E formation: use of ecarin for isolation of meizothrombin 1.
    Novoa E, Seegers WH.
    Thromb Res; 1980 Jun 01; 18(5):657-68. PubMed ID: 6998042
    [No Abstract] [Full Text] [Related]

  • 14. The effect of thrombin on astrocyte stellation with regional specificity.
    Koh PO, Kang BI, Kim GS, Oh YS, Won CK.
    J Vet Med Sci; 2005 Oct 01; 67(10):1047-50. PubMed ID: 16276062
    [Abstract] [Full Text] [Related]

  • 15. Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase.
    Ishida Y, Nagai A, Kobayashi S, Kim SU.
    J Neuropathol Exp Neurol; 2006 Jan 01; 65(1):66-77. PubMed ID: 16410750
    [Abstract] [Full Text] [Related]

  • 16. Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite.
    Wu Q, Tsiang M, Sadler JE.
    J Biol Chem; 1992 Dec 05; 267(34):24408-12. PubMed ID: 1332957
    [Abstract] [Full Text] [Related]

  • 17. Modulation of morphological differentiation of human neuroepithelial cells by serine proteases: independence from blood coagulation.
    Grand RJ, Grabham PW, Gallimore MJ, Gallimore PH.
    EMBO J; 1989 Aug 05; 8(8):2209-15. PubMed ID: 2792085
    [Abstract] [Full Text] [Related]

  • 18. Prothrombin conversion intermediate effectively neutralizes toxic levels of hirudin.
    Nowak G, Bucha E.
    Thromb Res; 1995 Nov 15; 80(4):317-25. PubMed ID: 8585044
    [Abstract] [Full Text] [Related]

  • 19. [Activation of the anticlotting system by perfusion of the carotid sinus with prethrombin 1 in rabbits].
    Strukova SM, Mitroshina TN, Umarova BA, Kudriashov BA.
    Fiziol Zh SSSR Im I M Sechenova; 1981 Dec 15; 67(12):1823-7. PubMed ID: 7333375
    [Abstract] [Full Text] [Related]

  • 20. Deletion of the 60-loop provides new insights into the substrate and inhibitor specificity of thrombin.
    Rezaie AR, Yang L.
    Thromb Haemost; 2005 Jun 15; 93(6):1047-54. PubMed ID: 15968387
    [Abstract] [Full Text] [Related]


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