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Journal Abstract Search

105 related items for PubMed ID: 10447948

  • 1. Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
    Bucholtz EC, Brown RL, Tropsha A, Booth RG, Wyrick SD.
    J Med Chem; 1999 Aug 12; 42(16):3041-54. PubMed ID: 10447948
    [Abstract] [Full Text] [Related]

  • 2. Putative sigma(3) sites in mammalian brain have histamine H(1) receptor properties: evidence from ligand binding and distribution studies with the novel H(1) radioligand [(3)H]-(-)-trans-1-phenyl-3-aminotetralin.
    Booth RG, Owens CE, Brown RL, Bucholtz EC, Lawler CP, Wyrick SD.
    Brain Res; 1999 Aug 07; 837(1-2):95-105. PubMed ID: 10433992
    [Abstract] [Full Text] [Related]

  • 3. A novel phenylaminotetralin (PAT) recognizes histamine H1 receptors and stimulates dopamine synthesis in vivo in rat brain.
    Choksi NY, Nix WB, Wyrick SD, Booth RG.
    Brain Res; 2000 Jan 03; 852(1):151-60. PubMed ID: 10661506
    [Abstract] [Full Text] [Related]

  • 4. 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes and related derivatives as ligands for the neuromodulatory sigma 3 receptor: further structure-activity relationships.
    Wyrick SD, Booth RG, Myers AM, Owens CE, Bucholtz EC, Hooper PC, Kula NS, Baldessarini RJ, Mailman RB.
    J Med Chem; 1995 Sep 15; 38(19):3857-64. PubMed ID: 7562917
    [Abstract] [Full Text] [Related]

  • 5. A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.
    Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R.
    J Pharmacol Exp Ther; 2002 Jul 15; 302(1):328-36. PubMed ID: 12065734
    [Abstract] [Full Text] [Related]

  • 6. Pharmacological differences between human and guinea pig histamine H1 receptors: Asn84 (2.61) as key residue within an additional binding pocket in the H1 receptor.
    Bruysters M, Jongejan A, Gillard M, van de Manakker F, Bakker RA, Chatelain P, Leurs R.
    Mol Pharmacol; 2005 Apr 15; 67(4):1045-52. PubMed ID: 15626750
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
    Strasser A, Striegl B, Wittmann HJ, Seifert R.
    J Pharmacol Exp Ther; 2008 Jan 15; 324(1):60-71. PubMed ID: 17928567
    [Abstract] [Full Text] [Related]

  • 8. QSAR study on binding affinity of PATs (rodenticides) to the [3H]-mepyramine-labelled H1 receptor in rat and guinea pig brain.
    Agrawal VK, Karmarkar S, Khadikar PV.
    SAR QSAR Environ Res; 2001 Jan 15; 12(6):529-45. PubMed ID: 11813804
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists.
    Terzioglu N, van Rijn RM, Bakker RA, De Esch IJ, Leurs R.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5251-6. PubMed ID: 15454206
    [Abstract] [Full Text] [Related]

  • 10. Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes.
    Ghoneim OM, Legere JA, Golbraikh A, Tropsha A, Booth RG.
    Bioorg Med Chem; 2006 Oct 01; 14(19):6640-58. PubMed ID: 16782354
    [Abstract] [Full Text] [Related]

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  • 12. Effects of impromidine- and arpromidine-derived guanidines on recombinant human and guinea pig histamine H1 and H2 receptors.
    Xie SX, Schalkhausser F, Ye QZ, Seifert R, Buschauer A.
    Arch Pharm (Weinheim); 2007 Jan 01; 340(1):9-16. PubMed ID: 17206612
    [Abstract] [Full Text] [Related]

  • 13. Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
    Wittmann HJ, Seifert R, Strasser A.
    Biochem Pharmacol; 2011 Dec 15; 82(12):1910-8. PubMed ID: 21933664
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.
    Govoni M, Bakker RA, van de Wetering I, Smit MJ, Menge WM, Timmerman H, Elz S, Schunack W, Leurs R.
    J Med Chem; 2003 Dec 18; 46(26):5812-24. PubMed ID: 14667234
    [Abstract] [Full Text] [Related]

  • 15. Comparison of the binding distribution of agonist and antagonist ligands for histamine H3 receptors in pig brain by quantitative autoradiography.
    Mezzomo K, Cumming P, Minuzzi L.
    Eur J Pharmacol; 2007 Jun 14; 564(1-3):75-9. PubMed ID: 17350614
    [Abstract] [Full Text] [Related]

  • 16. Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H(1)-receptor.
    Wittmann HJ, Seifert R, Strasser A.
    Mol Pharmacol; 2009 Jul 14; 76(1):25-37. PubMed ID: 19346300
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  • 19. Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor.
    Strasser A, Wittmann HJ, Kunze M, Elz S, Seifert R.
    Mol Pharmacol; 2009 Mar 14; 75(3):454-65. PubMed ID: 19047480
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity.
    Wyrick SD, Booth RG, Myers AM, Owens CE, Kula NS, Baldessarini RJ, McPhail AT, Mailman RB.
    J Med Chem; 1993 Aug 20; 36(17):2542-51. PubMed ID: 8102651
    [Abstract] [Full Text] [Related]

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