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Journal Abstract Search
320 related items for PubMed ID: 10449521
1. Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. Ward AC, van Aesch YM, Gits J, Schelen AM, de Koning JP, van Leeuwen D, Freedman MH, Touw IP. J Exp Med; 1999 Aug 16; 190(4):497-507. PubMed ID: 10449521 [Abstract] [Full Text] [Related]
2. Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals. Dror Y, Ward AC, Touw IP, Freedman MH. Exp Hematol; 2000 Dec 16; 28(12):1381-9. PubMed ID: 11146160 [Abstract] [Full Text] [Related]
3. Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene. Hermans MH, Antonissen C, Ward AC, Mayen AE, Ploemacher RE, Touw IP. J Exp Med; 1999 Feb 15; 189(4):683-92. PubMed ID: 9989983 [Abstract] [Full Text] [Related]
4. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. Dong F, Brynes RK, Tidow N, Welte K, Löwenberg B, Touw IP. N Engl J Med; 1995 Aug 24; 333(8):487-93. PubMed ID: 7542747 [Abstract] [Full Text] [Related]
5. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Tidow N, Pilz C, Teichmann B, Müller-Brechlin A, Germeshausen M, Kasper B, Rauprich P, Sykora KW, Welte K. Blood; 1997 Apr 01; 89(7):2369-75. PubMed ID: 9116280 [Abstract] [Full Text] [Related]
6. Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia. Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR. Blood; 2005 Jan 15; 105(2):584-91. PubMed ID: 15353486 [Abstract] [Full Text] [Related]
7. Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia. McLemore ML, Poursine-Laurent J, Link DC. J Clin Invest; 1998 Aug 01; 102(3):483-92. PubMed ID: 9691084 [Abstract] [Full Text] [Related]
8. Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia. Ward AC, Gits J, Majeed F, Aprikyan AA, Lewis RS, O'Sullivan LA, Freedman M, Shigdar S, Touw IP, Dale DC, Dror Y. Br J Haematol; 2008 Aug 01; 142(4):653-6. PubMed ID: 18513286 [Abstract] [Full Text] [Related]
9. Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration. Ward AC, Hermans MH, Smith L, van Aesch YM, Schelen AM, Antonissen C, Touw IP. Blood; 1999 Jan 01; 93(1):113-24. PubMed ID: 9864153 [Abstract] [Full Text] [Related]
10. Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia. Dong F, Hoefsloot LH, Schelen AM, Broeders CA, Meijer Y, Veerman AJ, Touw IP, Löwenberg B. Proc Natl Acad Sci U S A; 1994 May 10; 91(10):4480-4. PubMed ID: 7514305 [Abstract] [Full Text] [Related]
11. Frequency of point mutations in the gene for the G-CSF receptor in patients with chronic neutropenia undergoing G-CSF therapy. Tidow N, Pilz C, Kasper B, Welte K. Stem Cells; 1997 May 10; 15 Suppl 1():113-9; discussion 120. PubMed ID: 9368331 [Abstract] [Full Text] [Related]
12. The carboxyl terminus of the granulocyte colony-stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation. Dong F, Qiu Y, Yi T, Touw IP, Larner AC. J Immunol; 2001 Dec 01; 167(11):6447-52. PubMed ID: 11714811 [Abstract] [Full Text] [Related]
13. Severe congenital neutropenia terminating in acute myeloid leukemia: disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene. Touw IP, Dong F. Leuk Res; 1996 Aug 01; 20(8):629-31. PubMed ID: 8913314 [Abstract] [Full Text] [Related]
14. Structural abnormalities in the G-CSF receptor in severe congenital neutropenia. Deshpande RV, Lalezari P, Pergolizzi RG, Moore MA. J Hematother Stem Cell Res; 1999 Aug 01; 8(4):411-20. PubMed ID: 10634179 [Abstract] [Full Text] [Related]
15. G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact. van de Geijn GJ, Gits J, Aarts LH, Heijmans-Antonissen C, Touw IP. Blood; 2004 Aug 01; 104(3):667-74. PubMed ID: 15069015 [Abstract] [Full Text] [Related]
16. Deletional mutation of the external domain of the human granulocyte colony-stimulating factor receptor in a patient with severe chronic neutropenia refractory to granulocyte colony-stimulating factor. Sinha S, Zhu QS, Romero G, Corey SJ. J Pediatr Hematol Oncol; 2003 Oct 01; 25(10):791-6. PubMed ID: 14528102 [Abstract] [Full Text] [Related]
17. A novel mutation in the juxtamembrane intracellular sequence of the granulocyte colony-stimulating factor (G-CSF) receptor gene in a patient with severe congenital neutropenia augments GCSF proliferation activity but not through the MAP kinase cascade. Yokoyama T, Okamura S, Asano Y, Kamezaki K, Numata A, Kakumitsu H, Shide K, Nakashima H, Taisuke K, Sekine Y, Mizuno Y, Okamura J, Matsuda T, Harada M, Yoshiyuki N, Shimoda K. Int J Hematol; 2005 Jul 01; 82(1):28-34. PubMed ID: 16229088 [Abstract] [Full Text] [Related]
18. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells. Hermans MH, van de Geijn GJ, Antonissen C, Gits J, van Leeuwen D, Ward AC, Touw IP. Blood; 2003 Apr 01; 101(7):2584-90. PubMed ID: 12468431 [Abstract] [Full Text] [Related]
19. Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia. Ward AC, van Aesch YM, Schelen AM, Touw IP. Blood; 1999 Jan 15; 93(2):447-58. PubMed ID: 9885206 [Abstract] [Full Text] [Related]
20. Expression of receptors for granulocyte colony-stimulating factor on neutrophils from patients with severe congenital neutropenia and cyclic neutropenia. Kyas U, Pietsch T, Welte K. Blood; 1992 Mar 01; 79(5):1144-7. PubMed ID: 1371412 [Abstract] [Full Text] [Related] Page: [Next] [New Search]