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342 related items for PubMed ID: 10451376

  • 1. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides.
    Dickinson LA, Trauger JW, Baird EE, Ghazal P, Dervan PB, Gottesfeld JM.
    Biochemistry; 1999 Aug 17; 38(33):10801-7. PubMed ID: 10451376
    [Abstract] [Full Text] [Related]

  • 2. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand.
    McBryant SJ, Baird EE, Trauger JW, Dervan PB, Gottesfeld JM.
    J Mol Biol; 1999 Mar 05; 286(4):973-81. PubMed ID: 10047474
    [Abstract] [Full Text] [Related]

  • 3. Regulation of gene expression by small molecules.
    Gottesfeld JM, Neely L, Trauger JW, Baird EE, Dervan PB.
    Nature; 1997 May 08; 387(6629):202-5. PubMed ID: 9144294
    [Abstract] [Full Text] [Related]

  • 4. Combinatorial determination of sequence specificity for nanomolar DNA-binding hairpin polyamides.
    Vashisht Gopal YN, Van Dyke MW.
    Biochemistry; 2003 Jun 10; 42(22):6891-903. PubMed ID: 12779344
    [Abstract] [Full Text] [Related]

  • 5. Regulation of gene expression with pyrrole-imidazole polyamides.
    Melander C, Burnett R, Gottesfeld JM.
    J Biotechnol; 2004 Aug 26; 112(1-2):195-220. PubMed ID: 15288953
    [Abstract] [Full Text] [Related]

  • 6. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M.
    Biochemistry; 2004 Sep 28; 43(38):12249-57. PubMed ID: 15379563
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides.
    Gearhart MD, Dickinson L, Ehley J, Melander C, Dervan PB, Wright PE, Gottesfeld JM.
    Biochemistry; 2005 Mar 22; 44(11):4196-203. PubMed ID: 15766247
    [Abstract] [Full Text] [Related]

  • 8. The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
    Pilch DS, Poklar N, Baird EE, Dervan PB, Breslauer KJ.
    Biochemistry; 1999 Feb 16; 38(7):2143-51. PubMed ID: 10026298
    [Abstract] [Full Text] [Related]

  • 9. Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA.
    White S, Baird EE, Dervan PB.
    Biochemistry; 1996 Sep 24; 35(38):12532-7. PubMed ID: 8823190
    [Abstract] [Full Text] [Related]

  • 10. Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.
    Kageyama Y, Sugiyama H, Ayame H, Iwai A, Fujii Y, Huang LE, Kizaka-Kondoh S, Hiraoka M, Kihara K.
    Acta Oncol; 2006 Sep 24; 45(3):317-24. PubMed ID: 16644575
    [Abstract] [Full Text] [Related]

  • 11. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L, Mackay H, Brown T, Nguyen B, Kluza J, Wilson WD, Lee M, Hartley JA.
    Biochemistry; 2009 Jun 23; 48(24):5679-88. PubMed ID: 19419200
    [Abstract] [Full Text] [Related]

  • 12. RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif.
    Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D.
    Proc Natl Acad Sci U S A; 2016 Nov 01; 113(44):12426-12431. PubMed ID: 27791148
    [Abstract] [Full Text] [Related]

  • 13. Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-beta1 promoter for treatment of progressive renal diseases.
    Matsuda H, Fukuda N, Ueno T, Tahira Y, Ayame H, Zhang W, Bando T, Sugiyama H, Saito S, Matsumoto K, Mugishima H, Serie K.
    J Am Soc Nephrol; 2006 Feb 01; 17(2):422-32. PubMed ID: 16371433
    [Abstract] [Full Text] [Related]

  • 14. Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.
    Wu J, Jupp R, Stenberg RM, Nelson JA, Ghazal P.
    J Virol; 1993 Dec 01; 67(12):7547-55. PubMed ID: 8230474
    [Abstract] [Full Text] [Related]

  • 15. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
    O'Hare CC, Uthe P, Mackay H, Blackmon K, Jones J, Brown T, Nguyen B, Wilson WD, Lee M, Hartley JA.
    Biochemistry; 2007 Oct 23; 46(42):11661-70. PubMed ID: 17910471
    [Abstract] [Full Text] [Related]

  • 16. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL, Staples AM, Howard CM, Horick SM, Uthe PB, Le NM, Cox KK, Nguyen B, Pacheco KA, Wilson WD, Lee M.
    J Am Chem Soc; 2005 Jan 19; 127(2):742-50. PubMed ID: 15643900
    [Abstract] [Full Text] [Related]

  • 17. Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair.
    Briehn CA, Weyermann P, Dervan PB.
    Chemistry; 2003 May 09; 9(9):2110-22. PubMed ID: 12740860
    [Abstract] [Full Text] [Related]

  • 18. Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides.
    Gottesfeld JM, Melander C, Suto RK, Raviol H, Luger K, Dervan PB.
    J Mol Biol; 2001 Jun 08; 309(3):615-29. PubMed ID: 11397084
    [Abstract] [Full Text] [Related]

  • 19. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands.
    White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB.
    Nature; 1998 Jan 29; 391(6666):468-71. PubMed ID: 9461213
    [Abstract] [Full Text] [Related]

  • 20. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition.
    Shinohara K, Bando T, Sugiyama H.
    Anticancer Drugs; 2010 Mar 29; 21(3):228-42. PubMed ID: 20038830
    [Abstract] [Full Text] [Related]

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