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Journal Abstract Search

147 related items for PubMed ID: 10460801

  • 1. Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli.
    McGinnity DF, Griffin SJ, Moody GC, Voice M, Hanlon S, Friedberg T, Riley RJ.
    Drug Metab Dispos; 1999 Sep; 27(9):1017-23. PubMed ID: 10460801
    [Abstract] [Full Text] [Related]

  • 2. Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s.
    McGinnity DF, Parker AJ, Soars M, Riley RJ.
    Drug Metab Dispos; 2000 Nov; 28(11):1327-34. PubMed ID: 11038161
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  • 4. Utility of intersystem extrapolation factors in early reaction phenotyping and the quantitative extrapolation of human liver microsomal intrinsic clearance using recombinant cytochromes P450.
    Chen Y, Liu L, Nguyen K, Fretland AJ.
    Drug Metab Dispos; 2011 Mar; 39(3):373-82. PubMed ID: 21148079
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  • 5. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
    Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.
    Eur Neuropsychopharmacol; 2004 May; 14(3):199-208. PubMed ID: 15056479
    [Abstract] [Full Text] [Related]

  • 6. Multiple cytochrome P-450s involved in the metabolism of terbinafine suggest a limited potential for drug-drug interactions.
    Vickers AE, Sinclair JR, Zollinger M, Heitz F, Glänzel U, Johanson L, Fischer V.
    Drug Metab Dispos; 1999 Sep; 27(9):1029-38. PubMed ID: 10460803
    [Abstract] [Full Text] [Related]

  • 7. Human cytochrome P-450 metabolism of retinals to retinoic acids.
    Zhang QY, Dunbar D, Kaminsky L.
    Drug Metab Dispos; 2000 Mar; 28(3):292-7. PubMed ID: 10681373
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  • 8. Predicting drug pharmacokinetics in humans from in vitro metabolism studies.
    McGinnity DF, Riley RJ.
    Biochem Soc Trans; 2001 May; 29(Pt 2):135-9. PubMed ID: 11356141
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  • 9. Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches.
    Venkatakrishnan K, von Moltke LL, Court MH, Harmatz JS, Crespi CL, Greenblatt DJ.
    Drug Metab Dispos; 2000 Dec; 28(12):1493-504. PubMed ID: 11095589
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  • 10. Autoactivation and activation of the cytochrome P450s.
    Ekins S, Ring BJ, Binkley SN, Hall SD, Wrighton SA.
    Int J Clin Pharmacol Ther; 1998 Dec; 36(12):642-51. PubMed ID: 9877001
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  • 11. In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol.
    Usmani KA, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Dec 07; 150(3):221-32. PubMed ID: 15560889
    [Abstract] [Full Text] [Related]

  • 12. Metabolism of the antidepressant mirtazapine in vitro: contribution of cytochromes P-450 1A2, 2D6, and 3A4.
    Störmer E, von Moltke LL, Shader RI, Greenblatt DJ.
    Drug Metab Dispos; 2000 Oct 07; 28(10):1168-75. PubMed ID: 10997935
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  • 13. In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam.
    Tang J, Amin Usmani K, Hodgson E, Rose RL.
    Chem Biol Interact; 2004 Apr 15; 147(3):319-29. PubMed ID: 15135087
    [Abstract] [Full Text] [Related]

  • 14. Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver.
    Mutch E, Williams FM.
    Toxicology; 2006 Jul 05; 224(1-2):22-32. PubMed ID: 16757081
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of recombinant cytochrome P450 enzymes as an in vitro system for metabolic clearance predictions.
    Stringer RA, Strain-Damerell C, Nicklin P, Houston JB.
    Drug Metab Dispos; 2009 May 05; 37(5):1025-34. PubMed ID: 19196847
    [Abstract] [Full Text] [Related]

  • 16. Eight inhibitory monoclonal antibodies define the role of individual P-450s in human liver microsomal diazepam, 7-ethoxycoumarin, and imipramine metabolism.
    Yang TJ, Krausz KW, Sai Y, Gonzalez FJ, Gelboin HV.
    Drug Metab Dispos; 1999 Jan 05; 27(1):102-9. PubMed ID: 9884317
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  • 18. Scaling drug biotransformation data from cDNA-expressed cytochrome P-450 to human liver: a comparison of relative activity factors and human liver abundance in studies of mirtazapine metabolism.
    Störmer E, von Moltke LL, Greenblatt DJ.
    J Pharmacol Exp Ther; 2000 Nov 05; 295(2):793-801. PubMed ID: 11046120
    [Abstract] [Full Text] [Related]

  • 19. Organophosphorothionate pesticides inhibit the bioactivation of imipramine by human hepatic cytochrome P450s.
    Di Consiglio E, Meneguz A, Testai E.
    Toxicol Appl Pharmacol; 2005 Jun 15; 205(3):237-46. PubMed ID: 15922009
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