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PUBMED FOR HANDHELDS

Journal Abstract Search


392 related items for PubMed ID: 10464025

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  • 3. Synthesis, anti-HIV activity, and molecular mechanism of drug resistance of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
    Choo H, Chong Y, Choi Y, Mathew J, Schinazi RF, Chu CK.
    J Med Chem; 2003 Jan 30; 46(3):389-98. PubMed ID: 12540238
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  • 4. Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
    Wang J, Jin Y, Rapp KL, Bennett M, Schinazi RF, Chu CK.
    J Med Chem; 2005 Jun 02; 48(11):3736-48. PubMed ID: 15916425
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  • 5. l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.
    Chong Y, Gumina G, Mathew JS, Schinazi RF, Chu CK.
    J Med Chem; 2003 Jul 17; 46(15):3245-56. PubMed ID: 12852755
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  • 6. Synthesis and antiviral activities of enantiomeric 1-[2-(hydroxymethyl) cyclopropyl] methyl nucleosides.
    Pierra C, Olgen S, Cavalcanti SC, Cheng YC, Schinazi RF, Chu CK.
    Nucleosides Nucleotides Nucleic Acids; 2000 Jul 17; 19(1-2):253-68. PubMed ID: 10772713
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  • 9. Application of phosphoramidate ProTide technology significantly improves antiviral potency of carbocyclic adenosine derivatives.
    McGuigan C, Hassan-Abdallah A, Srinivasan S, Wang Y, Siddiqui A, Daluge SM, Gudmundsson KS, Zhou H, McLean EW, Peckham JP, Burnette TC, Marr H, Hazen R, Condreay LD, Johnson L, Balzarini J.
    J Med Chem; 2006 Nov 30; 49(24):7215-26. PubMed ID: 17125274
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  • 10. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
    Shi J, McAtee JJ, Schlueter Wirtz S, Tharnish P, Juodawlkis A, Liotta DC, Schinazi RF.
    J Med Chem; 1999 Mar 11; 42(5):859-67. PubMed ID: 10072683
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  • 11. Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
    Chong Y, Choo H, Choi Y, Mathew J, Schinazi RF, Chu CK.
    J Med Chem; 2002 Oct 24; 45(22):4888-98. PubMed ID: 12383014
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  • 13. Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.
    Zhou S, Breitenbach JM, Borysko KZ, Drach JC, Kern ER, Gullen E, Cheng YC, Zemlicka J.
    J Med Chem; 2004 Jan 29; 47(3):566-75. PubMed ID: 14736238
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  • 14. Synthesis of L-3'-hydroxymethylribonucleosides.
    Cooperwood JS, Boyd V, Gumina G, Chu CK.
    Nucleosides Nucleotides Nucleic Acids; 2000 Jan 29; 19(1-2):219-36. PubMed ID: 10772711
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  • 15. Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.
    Pélicano H, Pierra C, Eriksson S, Gosselin G, Imbach JL, Maury G.
    J Med Chem; 1997 Nov 21; 40(24):3969-73. PubMed ID: 9397178
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  • 18. Asymmetric synthesis and anti-HIV activity of L-carbocyclic 2',3'-didehydro-2',3'-dideoxyadenosine.
    Wang P, Schinazi RF, Chu CK.
    Bioorg Med Chem Lett; 1998 Jul 07; 8(13):1585-8. PubMed ID: 9873395
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  • 20. Synthesis, anti-human immunodeficiency virus and anti-hepatitis B virus activities of novel oxaselenolane nucleosides.
    Du J, Surzhykov S, Lin JS, Newton MG, Cheng YC, Schinazi RF, Chu CK.
    J Med Chem; 1997 Sep 12; 40(19):2991-3. PubMed ID: 9301659
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