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130 related items for PubMed ID: 10468636
1. Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA. Belcourt MF, Penketh PG, Hodnick WF, Johnson DA, Sherman DH, Rockwell S, Sartorelli AC. Proc Natl Acad Sci U S A; 1999 Aug 31; 96(18):10489-94. PubMed ID: 10468636 [Abstract] [Full Text] [Related]
2. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells. Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC. Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791 [Abstract] [Full Text] [Related]
3. Inducible synthesis of the mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae. August PR, Rahn JA, Flickinger MC, Sherman DH. Gene; 1996 Oct 10; 175(1-2):261-7. PubMed ID: 8917108 [Abstract] [Full Text] [Related]
5. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells. Fracasso PM, Sartorelli AC. Cancer Res; 1986 Aug 10; 46(8):3939-44. PubMed ID: 3089583 [Abstract] [Full Text] [Related]
6. Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Proc Natl Acad Sci U S A; 1996 Jan 09; 93(1):456-60. PubMed ID: 8552660 [Abstract] [Full Text] [Related]
7. Cloning and analysis of a locus (mcr) involved in mitomycin C resistance in Streptomyces lavendulae. August PR, Flickinger MC, Sherman DH. J Bacteriol; 1994 Jul 09; 176(14):4448-54. PubMed ID: 7517396 [Abstract] [Full Text] [Related]
8. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Adv Enzyme Regul; 1998 Jul 09; 38():111-33. PubMed ID: 9762350 [Abstract] [Full Text] [Related]
11. Decreased NADPH:cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions. Hoban PR, Walton MI, Robson CN, Godden J, Stratford IJ, Workman P, Harris AL, Hickson ID. Cancer Res; 1990 Aug 01; 50(15):4692-7. PubMed ID: 2114946 [Abstract] [Full Text] [Related]
12. Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase. Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC. Biochem Pharmacol; 1996 Jun 28; 51(12):1669-78. PubMed ID: 8687482 [Abstract] [Full Text] [Related]
13. Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics. Pritsos CA, Keyes SR, Sartorelli AC. Cancer Biochem Biophys; 1989 Oct 28; 10(4):289-98. PubMed ID: 2559790 [Abstract] [Full Text] [Related]
14. Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions. Seow HA, Penketh PG, Belcourt MF, Tomasz M, Rockwell S, Sartorelli AC. J Biol Chem; 2004 Jul 23; 279(30):31606-12. PubMed ID: 15155746 [Abstract] [Full Text] [Related]
16. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines. Kim SY, Rockwell S. Oncol Res; 1995 Jul 23; 7(5):39-47. PubMed ID: 8534933 [Abstract] [Full Text] [Related]
17. Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cells. Marshall RS, Rauth AM. Cancer Res; 1988 Oct 15; 48(20):5655-9. PubMed ID: 3167822 [Abstract] [Full Text] [Related]
18. Characterization of a mitomycin-binding drug resistance mechanism from the producing organism, Streptomyces lavendulae. Sheldon PJ, Johnson DA, August PR, Liu HW, Sherman DH. J Bacteriol; 1997 Mar 15; 179(5):1796-804. PubMed ID: 9045843 [Abstract] [Full Text] [Related]
19. Effects of mitomycin C and porfiromycin on exponentially growing and plateau phase cultures. Rockwell S, Hughes CS. Cell Prolif; 1994 Mar 15; 27(3):153-63. PubMed ID: 10465006 [Abstract] [Full Text] [Related]
20. Cytotoxicity and DNA crosslinks produced by mitomycin analogs in aerobic and hypoxic EMT6 cells. Keyes SR, Loomis R, DiGiovanna MP, Pritsos CA, Rockwell S, Sartorelli AC. Cancer Commun; 1991 Mar 15; 3(10-11):351-6. PubMed ID: 1760250 [Abstract] [Full Text] [Related] Page: [Next] [New Search]