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Journal Abstract Search

357 related items for PubMed ID: 10471495

  • 1. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
    Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF.
    Nat Genet; 1999 Sep; 23(1):32-40. PubMed ID: 10471495
    [Abstract] [Full Text] [Related]

  • 2. Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.
    Hennige AM, Ozcan U, Okada T, Jhala US, Schubert M, White MF, Kulkarni RN.
    Am J Physiol Endocrinol Metab; 2005 Aug; 289(2):E337-46. PubMed ID: 15827066
    [Abstract] [Full Text] [Related]

  • 3. IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.
    Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M.
    J Neurochem; 2008 Nov; 107(4):907-17. PubMed ID: 18717815
    [Abstract] [Full Text] [Related]

  • 4. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
    Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D.
    J Clin Invest; 2000 Jan; 105(2):199-205. PubMed ID: 10642598
    [Abstract] [Full Text] [Related]

  • 5. beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.
    Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR.
    Nat Genet; 2002 May; 31(1):111-5. PubMed ID: 11923875
    [Abstract] [Full Text] [Related]

  • 6. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT.
    Mol Cell Biol; 2007 May; 27(10):3569-77. PubMed ID: 17325037
    [Abstract] [Full Text] [Related]

  • 7. Exendin-4 and exercise promotes beta-cell function and mass through IRS2 induction in islets of diabetic rats.
    Park S, Hong SM, Sung SR.
    Life Sci; 2008 Feb 27; 82(9-10):503-11. PubMed ID: 18237751
    [Abstract] [Full Text] [Related]

  • 8. Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.
    Sun H, Tu X, Liu M, Baserga R.
    J Cell Physiol; 2007 Sep 27; 212(3):780-6. PubMed ID: 17443674
    [Abstract] [Full Text] [Related]

  • 9. Increased IRS-2 content and activation of IGF-I pathway contribute to enhance beta-cell mass in fetuses from undernourished pregnant rats.
    Fernández E, Martín MA, Fajardo S, Escrivá F, Alvarez C.
    Am J Physiol Endocrinol Metab; 2007 Jan 27; 292(1):E187-95. PubMed ID: 16912057
    [Abstract] [Full Text] [Related]

  • 10. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines.
    Jackson JG, Zhang X, Yoneda T, Yee D.
    Oncogene; 2001 Nov 01; 20(50):7318-25. PubMed ID: 11704861
    [Abstract] [Full Text] [Related]

  • 11. Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
    Sadagurski M, Yakar S, Weingarten G, Holzenberger M, Rhodes CJ, Breitkreutz D, Leroith D, Wertheimer E.
    Mol Cell Biol; 2006 Apr 01; 26(7):2675-87. PubMed ID: 16537911
    [Abstract] [Full Text] [Related]

  • 12. IRS proteins and the common path to diabetes.
    White MF.
    Am J Physiol Endocrinol Metab; 2002 Sep 01; 283(3):E413-22. PubMed ID: 12169433
    [Abstract] [Full Text] [Related]

  • 13. Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt.
    Hadsell DL, Olea W, Lawrence N, George J, Torres D, Kadowaki T, Lee AV.
    J Endocrinol; 2007 Aug 01; 194(2):327-36. PubMed ID: 17641282
    [Abstract] [Full Text] [Related]

  • 14. Insulin signalling in islets.
    Persaud SJ, Muller D, Jones PM.
    Biochem Soc Trans; 2008 Jun 01; 36(Pt 3):290-3. PubMed ID: 18481944
    [Abstract] [Full Text] [Related]

  • 15. ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.
    Minami K, Morita M, Saraya A, Yano H, Terauchi Y, Miki T, Kuriyama T, Kadowaki T, Seino S.
    Am J Physiol Endocrinol Metab; 2003 Dec 01; 285(6):E1289-96. PubMed ID: 12933351
    [Abstract] [Full Text] [Related]

  • 16. Role of glucose in IRS signaling in rat pancreatic islets: specific effects and interplay with insulin.
    Paris M, Bernard-Kargar C, Vilar J, Kassis N, Ktorza A.
    Exp Diabesity Res; 2004 Dec 01; 5(4):257-63. PubMed ID: 15763940
    [Abstract] [Full Text] [Related]

  • 17. Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.
    Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T.
    Diabetes Obes Metab; 2008 Nov 01; 10 Suppl 4():147-56. PubMed ID: 18834442
    [Abstract] [Full Text] [Related]

  • 18. High-fructose diet preserves beta-cell mass and prevents diabetes in nonobese diabetic mice: A potential role for increased insulin receptor substrate-2 expression.
    Orban T, Landaker E, Ruan Z, Cordeman TP, Weitgasser R, Bonner-Weir S, Jackson RA, Patti ME.
    Metabolism; 2001 Nov 01; 50(11):1369-76. PubMed ID: 11699059
    [Abstract] [Full Text] [Related]

  • 19. Type 2 diabetes-a matter of beta-cell life and death?
    Rhodes CJ.
    Science; 2005 Jan 21; 307(5708):380-4. PubMed ID: 15662003
    [Abstract] [Full Text] [Related]

  • 20. Pdx1 restores beta cell function in Irs2 knockout mice.
    Kushner JA, Ye J, Schubert M, Burks DJ, Dow MA, Flint CL, Dutta S, Wright CV, Montminy MR, White MF.
    J Clin Invest; 2002 May 21; 109(9):1193-201. PubMed ID: 11994408
    [Abstract] [Full Text] [Related]

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