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184 related items for PubMed ID: 10477559

  • 1. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4.
    Bresnahan PA, Yonemoto W, Greene WC.
    J Immunol; 1999 Sep 15; 163(6):2977-81. PubMed ID: 10477559
    [Abstract] [Full Text] [Related]

  • 2. The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC.
    Riggs NL, Craig HM, Pandori MW, Guatelli JC.
    Virology; 1999 Jun 05; 258(2):203-7. PubMed ID: 10366557
    [Abstract] [Full Text] [Related]

  • 3. Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.
    Cai CY, Zhang X, Sinko PJ, Burakoff SJ, Jin YJ.
    J Immunol; 2011 May 15; 186(10):5807-14. PubMed ID: 21482738
    [Abstract] [Full Text] [Related]

  • 4. Specific suppression of human CD4 surface expression by Nef from the pathogenic simian immunodeficiency virus SIVmac239open.
    Foster JL, Anderson SJ, Frazier AL, Garcia JV.
    Virology; 1994 Jun 15; 201(2):373-9. PubMed ID: 8184546
    [Abstract] [Full Text] [Related]

  • 5. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
    Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC.
    Curr Biol; 1998 Nov 05; 8(22):1235-8. PubMed ID: 9811606
    [Abstract] [Full Text] [Related]

  • 6. Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression.
    Swigut T, Iafrate AJ, Muench J, Kirchhoff F, Skowronski J.
    J Virol; 2000 Jun 05; 74(12):5691-701. PubMed ID: 10823877
    [Abstract] [Full Text] [Related]

  • 7. Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.
    Keppler OT, Tibroni N, Venzke S, Rauch S, Fackler OT.
    J Leukoc Biol; 2006 Mar 05; 79(3):616-27. PubMed ID: 16365153
    [Abstract] [Full Text] [Related]

  • 8. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis.
    Lock M, Greenberg ME, Iafrate AJ, Swigut T, Muench J, Kirchhoff F, Shohdy N, Skowronski J.
    EMBO J; 1999 May 17; 18(10):2722-33. PubMed ID: 10329619
    [Abstract] [Full Text] [Related]

  • 9. Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif.
    Craig HM, Reddy TR, Riggs NL, Dao PP, Guatelli JC.
    Virology; 2000 May 25; 271(1):9-17. PubMed ID: 10814565
    [Abstract] [Full Text] [Related]

  • 10. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.
    Münch J, Schindler M, Wildum S, Rücker E, Bailer N, Knoop V, Novembre FJ, Kirchhoff F.
    J Virol; 2005 Aug 25; 79(16):10547-60. PubMed ID: 16051847
    [Abstract] [Full Text] [Related]

  • 11. The acidic region and conserved putative protein kinase C phosphorylation site in Nef are important for SIV replication in rhesus macaques.
    Carl S, Iafrate AJ, Lang SM, Stahl-Hennig C, Kuhn EM, Fuchs D, Mätz-Rensing K, ten Haaft P, Heeney JL, Skowronski J, Kirchhoff F.
    Virology; 1999 Apr 25; 257(1):138-55. PubMed ID: 10208928
    [Abstract] [Full Text] [Related]

  • 12. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation.
    Greenberg ME, Bronson S, Lock M, Neumann M, Pavlakis GN, Skowronski J.
    EMBO J; 1997 Dec 01; 16(23):6964-76. PubMed ID: 9384576
    [Abstract] [Full Text] [Related]

  • 13. HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.
    Kim YH, Chang SH, Kwon JH, Rhee SS.
    Virology; 1999 Apr 25; 257(1):208-19. PubMed ID: 10208934
    [Abstract] [Full Text] [Related]

  • 14. Down-modulation of the costimulatory molecule, CD28, is a conserved activity of multiple SIV Nefs and is dependent on histidine 196 of Nef.
    Bell I, Schaefer TM, Trible RP, Amedee A, Reinhart TA.
    Virology; 2001 Apr 25; 283(1):148-58. PubMed ID: 11312671
    [Abstract] [Full Text] [Related]

  • 15. The conserved core of human immunodeficiency virus type 1 Nef is essential for association with Lck and for enhanced viral replication in T-lymphocytes.
    Cheng H, Hoxie JP, Parks WP.
    Virology; 1999 Nov 10; 264(1):5-15. PubMed ID: 10544125
    [Abstract] [Full Text] [Related]

  • 16. Structural and functional correlates between HIV-1 and SIV Nef isolates.
    Garcia JV, Foster JL.
    Virology; 1996 Dec 15; 226(2):161-6. PubMed ID: 8955034
    [Abstract] [Full Text] [Related]

  • 17. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.
    Greenberg ME, Iafrate AJ, Skowronski J.
    EMBO J; 1998 May 15; 17(10):2777-89. PubMed ID: 9582271
    [Abstract] [Full Text] [Related]

  • 18. Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef.
    Gratton S, Yao XJ, Venkatesan S, Cohen EA, Sékaly RP.
    J Immunol; 1996 Oct 15; 157(8):3305-11. PubMed ID: 8871625
    [Abstract] [Full Text] [Related]

  • 19. HIV pathogenesis: Nef loses control.
    Foster JL, Garcia JV.
    Cell; 2006 Jun 16; 125(6):1034-5. PubMed ID: 16777594
    [Abstract] [Full Text] [Related]

  • 20. Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
    Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F.
    Cell; 2006 Jun 16; 125(6):1055-67. PubMed ID: 16777597
    [Abstract] [Full Text] [Related]

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