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549 related items for PubMed ID: 10479282

  • 1. 8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation.
    Stefańska B, Dzieduszycka M, Bontemps-Gracz MM, Borowski E, Martelli S, Supino R, Pratesi G, De Cesare M, Zunino F, Kuśnierczyk H, Radzikowski C.
    J Med Chem; 1999 Sep 09; 42(18):3494-501. PubMed ID: 10479282
    [Abstract] [Full Text] [Related]

  • 2. Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts.
    Gourdeau H, Genne P, Kadhim S, Bibeau L, Duchamp O, Ouellet F, deMuys JM, Bouffard DY, Attardo G.
    Cancer Chemother Pharmacol; 2002 Dec 09; 50(6):490-6. PubMed ID: 12451476
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and antitumor evaluation of 2,5-disubstituted-indazolo[4, 3-gh]isoquinolin-6(2H)-ones (9-aza-anthrapyrazoles).
    Krapcho AP, Menta E, Oliva A, Di Domenico R, Fiocchi L, Maresch ME, Gallagher CE, Hacker MP, Beggiolin G, Giuliani FC, Pezzoni G, Spinelli S.
    J Med Chem; 1998 Dec 31; 41(27):5429-44. PubMed ID: 9876113
    [Abstract] [Full Text] [Related]

  • 4. (R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
    Kirshenbaum MR, Chen SF, Behrens CH, Papp LM, Stafford MM, Sun JH, Behrens DL, Fredericks JR, Polkus ST, Sipple P.
    Cancer Res; 1994 Apr 15; 54(8):2199-206. PubMed ID: 8174127
    [Abstract] [Full Text] [Related]

  • 5. Characterization of four drug-resistant P388 sublines: resistance/sensitivity in vivo, resistance-and proliferation-markers, immunogenicity.
    Fichtner I, Stein U, Hoffmann J, Winterfeld G, Pfeil D, Hentschel M.
    Anticancer Res; 1994 Apr 15; 14(5A):1995-2003. PubMed ID: 7847840
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D x 5 cells.
    Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Kletsas D.
    Bioorg Med Chem; 2006 May 01; 14(9):2910-34. PubMed ID: 16376546
    [Abstract] [Full Text] [Related]

  • 7. 6-[(aminoalkyl)amino]-substituted 7H-benzo[e]perimidin-7-ones as novel antineoplastic agents. Synthesis and biological evaluation.
    Stefańska B, Dzieduszycka M, Martelli S, Tarasiuk J, Bontemps-Gracz M, Borowski E.
    J Med Chem; 1993 Jan 08; 36(1):38-41. PubMed ID: 8421288
    [Abstract] [Full Text] [Related]

  • 8. Novel phosphonium salts display in vitro and in vivo cytotoxic activity against human ovarian cancer cell lines.
    Manetta A, Gamboa G, Nasseri A, Podnos YD, Emma D, Dorion G, Rawlings L, Carpenter PM, Bustamante A, Patel J, Rideout D.
    Gynecol Oncol; 1996 Feb 08; 60(2):203-12. PubMed ID: 8631539
    [Abstract] [Full Text] [Related]

  • 9. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps.
    Kasibhatla S, Baichwal V, Cai SX, Roth B, Skvortsova I, Skvortsov S, Lukas P, English NM, Sirisoma N, Drewe J, Pervin A, Tseng B, Carlson RO, Pleiman CM.
    Cancer Res; 2007 Jun 15; 67(12):5865-71. PubMed ID: 17575155
    [Abstract] [Full Text] [Related]

  • 10. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK, Chiu P, Chung SS, Chow LM, Zhao YZ, Yang BB, Ko BC.
    Clin Cancer Res; 2005 Aug 15; 11(16):6002-11. PubMed ID: 16115945
    [Abstract] [Full Text] [Related]

  • 11. DNA binding ellipticine analogues: synthesis, biological evaluation, and structure-activity relationships.
    Ferlin MG, Marzano C, Gandin V, Dall'Acqua S, Dalla Via L.
    ChemMedChem; 2009 Mar 15; 4(3):363-77. PubMed ID: 19197924
    [Abstract] [Full Text] [Related]

  • 12. Antimultidrug-resistant effect and mechanism of a novel CA-4 analogue MZ3 on leukemia cells.
    Xu D, Fang L, Zhu Q, Hu Y, He Q, Yang B.
    Pharmazie; 2008 Jul 15; 63(7):528-33. PubMed ID: 18717489
    [Abstract] [Full Text] [Related]

  • 13. Effect of modification of 6-[(aminoalkyl)amino]-7H-benzo[e]-perimidin-7-ones on their cytotoxic activity toward sensitive and multidrug resistant tumor cell lines. Synthesis and biological evaluation.
    Dzieduszycka M, Martelli S, Arciemiuk M, Bontemps-Gracz MM, Kupiec A, Borowski E.
    Bioorg Med Chem; 2002 Apr 15; 10(4):1025-35. PubMed ID: 11836111
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines.
    Dzieduszycka M, Bontemps-Gracz MM, Stefańska B, Martelli S, Piwkowska A, Arciemiuk M, Borowski E.
    Bioorg Med Chem; 2006 May 01; 14(9):2880-6. PubMed ID: 16458007
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of acquired resistance to methotrexate in P388 murine leukemia cells and in their doxorubicin-resistant subline.
    Ramu N, Ramu A, Cole DE, Balis FM, Poplack DG, Pollard HB.
    Isr J Med Sci; 1988 May 01; 24(9-10):477-82. PubMed ID: 2974448
    [Abstract] [Full Text] [Related]

  • 16. Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
    Newman MJ, Rodarte JC, Benbatoul KD, Romano SJ, Zhang C, Krane S, Moran EJ, Uyeda RT, Dixon R, Guns ES, Mayer LD.
    Cancer Res; 2000 Jun 01; 60(11):2964-72. PubMed ID: 10850444
    [Abstract] [Full Text] [Related]

  • 17. Effects of new antitumor bifunctional intercalators derived from 7H-pyridocarbazole on sensitive and resistant L 1210 cells.
    Esnault C, Roques BP, Jacquemin-Sablon A, Le Pecq JB.
    Cancer Res; 1984 Oct 01; 44(10):4355-60. PubMed ID: 6467197
    [Abstract] [Full Text] [Related]

  • 18. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
    Chang JY, Chang CY, Kuo CC, Chen LT, Wein YS, Kuo YH.
    Mol Pharmacol; 2004 Jan 01; 65(1):77-84. PubMed ID: 14722239
    [Abstract] [Full Text] [Related]

  • 19. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U, Lynch J, Sato Y, Kashimoto S, Kajikawa F, Furutani Y, Silverman JA.
    Cancer Chemother Pharmacol; 2009 Jun 01; 64(1):53-65. PubMed ID: 18931998
    [Abstract] [Full Text] [Related]

  • 20. 2,3-Dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione derivatives, a class of cytotoxic agents active on multidrug-resistant cell lines: synthesis, biological evaluation, and structure-activity relationships.
    Antonini I, Polucci P, Kelland LR, Menta E, Pescalli N, Martelli S.
    J Med Chem; 1999 Jul 15; 42(14):2535-41. PubMed ID: 10411474
    [Abstract] [Full Text] [Related]

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