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Journal Abstract Search

519 related items for PubMed ID: 10485490

  • 1. Decrease in susceptibility toward induction of apoptosis and alteration in G1 checkpoint function as determinants of resistance of human lung cancer cells against the antisignaling drug UCN-01 (7-Hydroxystaurosporine).
    Sugiyama K, Akiyama T, Shimizu M, Tamaoki T, Courage C, Gescher A, Akinaga S.
    Cancer Res; 1999 Sep 01; 59(17):4406-12. PubMed ID: 10485490
    [Abstract] [Full Text] [Related]

  • 2. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T, Yoshida T, Tsujita T, Shimizu M, Mizukami T, Okabe M, Akinaga S.
    Cancer Res; 1997 Apr 15; 57(8):1495-501. PubMed ID: 9108451
    [Abstract] [Full Text] [Related]

  • 3. Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
    Patel V, Lahusen T, Leethanakul C, Igishi T, Kremer M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS, Senderowicz AM.
    Clin Cancer Res; 2002 Nov 15; 8(11):3549-60. PubMed ID: 12429646
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  • 5. UCN-01 (7-hydoxystaurosporine) inhibits in vivo growth of human cancer cells through selective perturbation of G1 phase checkpoint machinery.
    Abe S, Kubota T, Otani Y, Furukawa T, Watanabe M, Kumai K, Akiyama T, Akinaga S, Kitajima M.
    Jpn J Cancer Res; 2001 May 15; 92(5):537-45. PubMed ID: 11376563
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  • 7. Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells.
    Chang GC, Hsu SL, Tsai JR, Liang FP, Lin SY, Sheu GT, Chen CY.
    Biochem Pharmacol; 2004 Oct 01; 68(7):1453-64. PubMed ID: 15345335
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  • 9. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S, Lowe M, Herliczek TW, Keyomarsi K.
    Oncogene; 1998 Nov 05; 17(18):2393-402. PubMed ID: 9811471
    [Abstract] [Full Text] [Related]

  • 10. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G, Barkan R, Popov B, Nikolsky N, Chang LS.
    Exp Cell Res; 2000 Aug 25; 259(1):35-53. PubMed ID: 10942577
    [Abstract] [Full Text] [Related]

  • 11. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
    Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH.
    Oncogene; 2001 May 24; 20(23):2927-36. PubMed ID: 11420705
    [Abstract] [Full Text] [Related]

  • 12. RB status as a determinant of response to UCN-01 in non-small cell lung carcinoma.
    Mack PC, Gandara DR, Bowen C, Edelman MJ, Paglieroni T, Schnier JB, Gelmann EP, Gumerlock PH.
    Clin Cancer Res; 1999 Sep 24; 5(9):2596-604. PubMed ID: 10499638
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL, Buffolino P, Kopman C, Nathanson L.
    Exp Cell Res; 1995 Nov 24; 221(1):92-102. PubMed ID: 7589260
    [Abstract] [Full Text] [Related]

  • 14. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes.
    Nahum A, Hirsch K, Danilenko M, Watts CK, Prall OW, Levy J, Sharoni Y.
    Oncogene; 2001 Jun 07; 20(26):3428-36. PubMed ID: 11423993
    [Abstract] [Full Text] [Related]

  • 15. Molecular determinants of UCN-01-induced growth inhibition in human lung cancer cells.
    Usuda J, Saijo N, Fukuoka K, Fukumoto H, Kuh HJ, Nakamura T, Koh Y, Suzuki T, Koizumi F, Tamura T, Kato H, Nishio K.
    Int J Cancer; 2000 Jan 15; 85(2):275-80. PubMed ID: 10629089
    [Abstract] [Full Text] [Related]

  • 16. Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.
    Meng LH, Zhang H, Hayward L, Takemura H, Shao RG, Pommier Y.
    Cancer Res; 2004 Dec 15; 64(24):9086-92. PubMed ID: 15604277
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
    Liang YC, Lin-Shiau SY, Chen CF, Lin JK.
    J Cell Biochem; 1999 Oct 01; 75(1):1-12. PubMed ID: 10462699
    [Abstract] [Full Text] [Related]

  • 18. Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells.
    Kim WH, Kang KH, Kim MY, Choi KH.
    Biochem Cell Biol; 2000 Oct 01; 78(2):127-35. PubMed ID: 10874474
    [Abstract] [Full Text] [Related]

  • 19. Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.
    Aranha O, Wood DP, Sarkar FH.
    Clin Cancer Res; 2000 Mar 01; 6(3):891-900. PubMed ID: 10741713
    [Abstract] [Full Text] [Related]

  • 20. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
    Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ.
    Cancer Res; 1996 Jul 01; 56(13):2973-8. PubMed ID: 8674031
    [Abstract] [Full Text] [Related]

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