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Journal Abstract Search

100 related items for PubMed ID: 10490916

  • 1. Metabolism of trimethoprim to a reactive iminoquinone methide by activated human neutrophils and hepatic microsomes.
    Lai WG, Zahid N, Uetrecht JP.
    J Pharmacol Exp Ther; 1999 Oct; 291(1):292-9. PubMed ID: 10490916
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  • 4. Oxidation of a metabolite of indomethacin (Desmethyldeschlorobenzoylindomethacin) to reactive intermediates by activated neutrophils, hypochlorous acid, and the myeloperoxidase system.
    Ju C, Uetrecht JP.
    Drug Metab Dispos; 1998 Jul; 26(7):676-80. PubMed ID: 9660850
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  • 5. Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
    Lai WG, Gardner I, Zahid N, Uetrecht JP.
    Drug Metab Dispos; 2000 Mar; 28(3):255-63. PubMed ID: 10681368
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  • 7. Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
    Liu ZC, Uetrecht JP.
    J Pharmacol Exp Ther; 1995 Dec; 275(3):1476-83. PubMed ID: 8531118
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  • 10. Electrochemical oxidation of troglitazone: identification and characterization of the major reactive metabolite in liver microsomes.
    Madsen KG, Grönberg G, Skonberg C, Jurva U, Hansen SH, Olsen J.
    Chem Res Toxicol; 2008 Oct; 21(10):2035-41. PubMed ID: 18788755
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  • 12. Oxidation of 5-aminosalicylic acid by hypochlorous acid to a reactive iminoquinone. Possible role in the treatment of inflammatory bowel diseases.
    Liu ZC, McClelland RA, Uetrecht JP.
    Drug Metab Dispos; 1995 Feb; 23(2):246-50. PubMed ID: 7736919
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  • 13. Protective effects of N-acetyl-L-cysteine against acute carbon tetrachloride hepatotoxicity in rats.
    Maksimchik YZ, Lapshina EA, Sudnikovich EY, Zabrodskaya SV, Zavodnik IB.
    Cell Biochem Funct; 2008 Feb; 26(1):11-8. PubMed ID: 17200984
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  • 14. Rapid detection and characterization of in vitro and urinary N-acetyl-L-cysteine conjugates using quadrupole-linear ion trap mass spectrometry and polarity switching.
    Jian W, Yao M, Zhang D, Zhu M.
    Chem Res Toxicol; 2009 Jul; 22(7):1246-55. PubMed ID: 19527004
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  • 16. Oxidation of propylthiouracil to reactive metabolites by activated neutrophils. Implications for agranulocytosis.
    Waldhauser L, Uetrecht J.
    Drug Metab Dispos; 1991 Jul; 19(2):354-9. PubMed ID: 1676636
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  • 19. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 20. The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man.
    Maggs JL, Williams D, Pirmohamed M, Park BK.
    J Pharmacol Exp Ther; 1995 Dec; 275(3):1463-75. PubMed ID: 8531117
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