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Journal Abstract Search

327 related items for PubMed ID: 10491012

  • 1. Depressed IL-12-mediated signal transduction in T cells from patients with Sézary syndrome is associated with the absence of IL-12 receptor beta 2 mRNA and highly reduced levels of STAT4.
    Showe LC, Fox FE, Williams D, Au K, Niu Z, Rook AH.
    J Immunol; 1999 Oct 01; 163(7):4073-9. PubMed ID: 10491012
    [Abstract] [Full Text] [Related]

  • 2. Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling.
    Nishikomori R, Usui T, Wu CY, Morinobu A, O'Shea JJ, Strober W.
    J Immunol; 2002 Oct 15; 169(8):4388-98. PubMed ID: 12370372
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes.
    Franchimont D, Galon J, Gadina M, Visconti R, Zhou Y, Aringer M, Frucht DM, Chrousos GP, O'Shea JJ.
    J Immunol; 2000 Feb 15; 164(4):1768-74. PubMed ID: 10657623
    [Abstract] [Full Text] [Related]

  • 4. An absolute requirement for STAT4 and a role for IFN-gamma as an amplifying factor in IL-12 induction of the functional IL-18 receptor complex.
    Nakahira M, Tomura M, Iwasaki M, Ahn HJ, Bian Y, Hamaoka T, Ohta T, Kurimoto M, Fujiwara H.
    J Immunol; 2001 Aug 01; 167(3):1306-12. PubMed ID: 11466347
    [Abstract] [Full Text] [Related]

  • 5. STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.
    Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, Feldman GM, Nishikomori R, O'Shea JJ.
    Proc Natl Acad Sci U S A; 2002 Sep 17; 99(19):12281-6. PubMed ID: 12213961
    [Abstract] [Full Text] [Related]

  • 6. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells.
    Szabo SJ, Dighe AS, Gubler U, Murphy KM.
    J Exp Med; 1997 Mar 03; 185(5):817-24. PubMed ID: 9120387
    [Abstract] [Full Text] [Related]

  • 7. Cutting edge: ectopic expression of the IL-12 receptor-beta 2 in developing and committed Th2 cells does not affect the production of IL-4 or induce the production of IFN-gamma.
    Heath VL, Showe L, Crain C, Barrat FJ, Trinchieri G, O'Garra A.
    J Immunol; 2000 Mar 15; 164(6):2861-5. PubMed ID: 10706670
    [Abstract] [Full Text] [Related]

  • 8. Selective expression of an interleukin-12 receptor component by human T helper 1 cells.
    Rogge L, Barberis-Maino L, Biffi M, Passini N, Presky DH, Gubler U, Sinigaglia F.
    J Exp Med; 1997 Mar 03; 185(5):825-31. PubMed ID: 9120388
    [Abstract] [Full Text] [Related]

  • 9. T helper differentiation proceeds through Stat1-dependent, Stat4-dependent and Stat4-independent phases.
    Murphy KM, Ouyang W, Szabo SJ, Jacobson NG, Guler ML, Gorham JD, Gubler U, Murphy TL.
    Curr Top Microbiol Immunol; 1999 Mar 03; 238():13-26. PubMed ID: 10087648
    [Abstract] [Full Text] [Related]

  • 10. Impairment of IL-12-dependent STAT4 nuclear translocation in a patient with recurrent Mycobacterium avium infection.
    Toyoda H, Ido M, Hayashi T, Gabazza EC, Suzuki K, Bu J, Tanaka S, Nakano T, Kamiya H, Chipeta J, Kisenge RR, Kang J, Hori H, Komada Y.
    J Immunol; 2004 Mar 15; 172(6):3905-12. PubMed ID: 15004198
    [Abstract] [Full Text] [Related]

  • 11. IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production.
    McDyer JF, Li Z, John S, Yu X, Wu CY, Ragheb JA.
    J Immunol; 2002 Sep 01; 169(5):2736-46. PubMed ID: 12193748
    [Abstract] [Full Text] [Related]

  • 12. Dysregulation of lymphocyte interleukin-12 receptor expression in Sézary syndrome.
    Zaki MH, Shane RB, Geng Y, Showe LC, Everetts SE, Presky DH, Wysocka M, Moore JS, Rook AH.
    J Invest Dermatol; 2001 Jul 01; 117(1):119-27. PubMed ID: 11442758
    [Abstract] [Full Text] [Related]

  • 13. TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes.
    Bright JJ, Sriram S.
    J Immunol; 1998 Aug 15; 161(4):1772-7. PubMed ID: 9712043
    [Abstract] [Full Text] [Related]

  • 14. The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4.
    Schindler H, Lutz MB, Röllinghoff M, Bogdan C.
    J Immunol; 2001 Mar 01; 166(5):3075-82. PubMed ID: 11207258
    [Abstract] [Full Text] [Related]

  • 15. Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression.
    Yin Z, Zhang DH, Welte T, Bahtiyar G, Jung S, Liu L, Fu XY, Ray A, Craft J.
    J Immunol; 2000 Mar 15; 164(6):3056-64. PubMed ID: 10706694
    [Abstract] [Full Text] [Related]

  • 16. A heritable defect in IL-12 signaling in B10.Q/J mice. I. In vitro analysis.
    Ortmann R, Smeltz R, Yap G, Sher A, Shevach EM.
    J Immunol; 2001 May 01; 166(9):5712-9. PubMed ID: 11313413
    [Abstract] [Full Text] [Related]

  • 17. Activated STAT4 and a functional role for IL-12 in human Peyer's patches.
    Monteleone G, Holloway J, Salvati VM, Pender SL, Fairclough PD, Croft N, MacDonald TT.
    J Immunol; 2003 Jan 01; 170(1):300-7. PubMed ID: 12496413
    [Abstract] [Full Text] [Related]

  • 18. A mandatory role for STAT4 in IL-12 induction of mouse T cell CCR5.
    Iwasaki M, Mukai T, Nakajima C, Yang YF, Gao P, Yamaguchi N, Tomura M, Fujiwara H, Hamaoka T.
    J Immunol; 2001 Dec 15; 167(12):6877-83. PubMed ID: 11739505
    [Abstract] [Full Text] [Related]

  • 19. Lack of IL-12 signaling in human allergen-specific Th2 cells.
    Hilkens CM, Messer G, Tesselaar K, van Rietschoten AG, Kapsenberg ML, Wierenga EA.
    J Immunol; 1996 Nov 15; 157(10):4316-21. PubMed ID: 8906805
    [Abstract] [Full Text] [Related]

  • 20. IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites.
    Wu C, Wang X, Gadina M, O'Shea JJ, Presky DH, Magram J.
    J Immunol; 2000 Dec 01; 165(11):6221-8. PubMed ID: 11086056
    [Abstract] [Full Text] [Related]

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