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137 related items for PubMed ID: 10493943

  • 1. 2-methoxyestradiol-induced growth suppression and lethality in estrogen-responsive MCF-7 cells may be mediated by down regulation of p34cdc2 and cyclin B1 expression.
    Zoubine MN, Weston AP, Johnson DC, Campbell DR, Banerjee SK.
    Int J Oncol; 1999 Oct; 15(4):639-46. PubMed ID: 10493943
    [Abstract] [Full Text] [Related]

  • 2. 2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells.
    Kumar AP, Garcia GE, Slaga TJ.
    Mol Carcinog; 2001 Jul; 31(3):111-24. PubMed ID: 11479920
    [Abstract] [Full Text] [Related]

  • 3. Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol.
    Choi HJ, Zhu BT.
    Biochim Biophys Acta; 2012 Aug; 1823(8):1306-15. PubMed ID: 22580043
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of action of a tyrphostin, 3,4-dihydroxy-alpha-cyanothiocinnamamide, in breast cancer cell growth inhibition involves the suppression of cyclin B1 and the functional activity of cyclin B1/p34cdc2 complex.
    Faaland CA, Adhikarakunnathu S, Thomas T, Thomas TJ.
    Breast Cancer Res Treat; 1997 May; 44(1):47-56. PubMed ID: 9164677
    [Abstract] [Full Text] [Related]

  • 5. Increased expression of cyclin B1 sensitizes prostate cancer cells to apoptosis induced by chemotherapy.
    Gomez LA, de Las Pozas A, Reiner T, Burnstein K, Perez-Stable C.
    Mol Cancer Ther; 2007 May; 6(5):1534-43. PubMed ID: 17513602
    [Abstract] [Full Text] [Related]

  • 6. Estrogen and progesterone lower cyclin B1 AND D1 expression, block cell cycle in G2/M, and trigger apoptosis in human adrenal carcinoma cell cultures.
    Brown JW, Prieto LM, Perez-Stable C, Montoya M, Cappell S, Fishman LM.
    Horm Metab Res; 2008 May; 40(5):306-10. PubMed ID: 18491248
    [Abstract] [Full Text] [Related]

  • 7. Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-XL phosphorylation.
    Choi HJ, Zhu BT.
    Steroids; 2019 Oct; 150():108381. PubMed ID: 30797877
    [Abstract] [Full Text] [Related]

  • 8. Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways.
    Ray G, Dhar G, Van Veldhuizen PJ, Banerjee S, Saxena NK, Sengupta K, Banerjee SK.
    Biochemistry; 2006 Mar 21; 45(11):3703-13. PubMed ID: 16533053
    [Abstract] [Full Text] [Related]

  • 9. Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells.
    Choi YH, Zhang L, Lee WH, Park KY.
    Int J Oncol; 1998 Aug 21; 13(2):391-6. PubMed ID: 9664138
    [Abstract] [Full Text] [Related]

  • 10. Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1.
    Aka JA, Calvo EL, Lin SX.
    Mol Cell Endocrinol; 2017 Jan 05; 439():175-186. PubMed ID: 27544780
    [Abstract] [Full Text] [Related]

  • 11. Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells.
    Yuan J, Yan R, Krämer A, Eckerdt F, Roller M, Kaufmann M, Strebhardt K.
    Oncogene; 2004 Jul 29; 23(34):5843-52. PubMed ID: 15208674
    [Abstract] [Full Text] [Related]

  • 12. 2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells.
    Maran A, Zhang M, Kennedy AM, Sibonga JD, Rickard DJ, Spelsberg TC, Turner RT.
    Bone; 2002 Feb 29; 30(2):393-8. PubMed ID: 11856647
    [Abstract] [Full Text] [Related]

  • 13. Effects of 2-methoxyestradiol on proliferation, apoptosis and gene expression of cyclin B1 and c-Myc in esophageal carcinoma EC9706 cells.
    Du B, Zhao Z, Sun H, Ma S, Jin J, Zhang Z.
    Cell Biochem Funct; 2012 Mar 29; 30(2):158-65. PubMed ID: 22095881
    [Abstract] [Full Text] [Related]

  • 14. Cell cycle-dependent cytotoxicity, G2/M phase arrest, and disruption of p34cdc2/cyclin B1 activity induced by doxorubicin in synchronized P388 cells.
    Ling YH, el-Naggar AK, Priebe W, Perez-Soler R.
    Mol Pharmacol; 1996 May 29; 49(5):832-41. PubMed ID: 8622633
    [Abstract] [Full Text] [Related]

  • 15. Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells.
    Foster JS, Wimalasena J.
    Mol Endocrinol; 1996 May 29; 10(5):488-98. PubMed ID: 8732680
    [Abstract] [Full Text] [Related]

  • 16. 2-Methoxyestradiol interferes with NF kappa B transcriptional activity in primitive neuroectodermal brain tumors: implications for management.
    Kumar AP, Garcia GE, Orsborn J, Levin VA, Slaga TJ.
    Carcinogenesis; 2003 Feb 29; 24(2):209-16. PubMed ID: 12584169
    [Abstract] [Full Text] [Related]

  • 17. Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
    Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, Thomas T.
    J Mol Endocrinol; 2005 Feb 29; 34(1):91-105. PubMed ID: 15691880
    [Abstract] [Full Text] [Related]

  • 18. Taxol-induced p34cdc2 kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells.
    Shen SC, Huang TS, Jee SH, Kuo ML.
    Cell Growth Differ; 1998 Jan 29; 9(1):23-9. PubMed ID: 9438385
    [Abstract] [Full Text] [Related]

  • 19. 1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.
    Swami S, Krishnan AV, Feldman D.
    Clin Cancer Res; 2000 Aug 29; 6(8):3371-9. PubMed ID: 10955825
    [Abstract] [Full Text] [Related]

  • 20. Expression of the G2-M checkpoint regulators cyclin B1 and P34CDC2 in breast cancer: a correlation with cellular kinetics.
    Megha T, Lazzi S, Ferrari F, Vatti R, Howard CM, Cevenini G, Leoncini L, Luzi P, Giordano A, Tosi P.
    Anticancer Res; 1999 Aug 29; 19(1A):163-9. PubMed ID: 10226538
    [Abstract] [Full Text] [Related]

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