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Journal Abstract Search

281 related items for PubMed ID: 10497255

  • 1. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.
    Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y.
    J Biol Chem; 1999 Oct 01; 274(40):28816-22. PubMed ID: 10497255
    [Abstract] [Full Text] [Related]

  • 2. Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins.
    Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y.
    J Biol Chem; 2001 Apr 27; 276(17):14459-65. PubMed ID: 11278339
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  • 3. Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.
    Greene MW, Sakaue H, Wang L, Alessi DR, Roth RA.
    J Biol Chem; 2003 Mar 07; 278(10):8199-211. PubMed ID: 12510059
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  • 4. Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.
    Liu YF, Herschkovitz A, Boura-Halfon S, Ronen D, Paz K, Leroith D, Zick Y.
    Mol Cell Biol; 2004 Nov 07; 24(21):9668-81. PubMed ID: 15485932
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  • 6. Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor.
    Wick KR, Werner ED, Langlais P, Ramos FJ, Dong LQ, Shoelson SE, Liu F.
    J Biol Chem; 2003 Mar 07; 278(10):8460-7. PubMed ID: 12493740
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  • 7. Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling.
    Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H, Christ-Roberts CY, Mandarino LJ.
    Endocrinology; 2007 Oct 07; 148(10):4895-905. PubMed ID: 17640984
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  • 8. Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.
    Liberman Z, Eldar-Finkelman H.
    J Biol Chem; 2005 Feb 11; 280(6):4422-8. PubMed ID: 15574412
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  • 10. Contraction inhibits insulin-stimulated insulin receptor substrate-1/2-associated phosphoinositide 3-kinase activity, but not protein kinase B activation or glucose uptake, in rat muscle.
    Whitehead JP, Soos MA, Aslesen R, O'rahilly S, Jensen J.
    Biochem J; 2000 Aug 01; 349 Pt 3(Pt 3):775-81. PubMed ID: 10903138
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  • 11. Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
    Müssig K, Staiger H, Fiedler H, Moeschel K, Beck A, Kellerer M, Häring HU.
    J Biol Chem; 2005 Sep 23; 280(38):32693-9. PubMed ID: 16055440
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  • 12. Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
    Wick MJ, Dong LQ, Hu D, Langlais P, Liu F.
    J Biol Chem; 2001 Nov 16; 276(46):42843-50. PubMed ID: 11551902
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  • 14. Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells.
    Hers I, Wherlock M, Homma Y, Yagisawa H, Tavaré JM.
    J Biol Chem; 2006 Feb 24; 281(8):4762-70. PubMed ID: 16338927
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  • 15. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A, Usui I, Haruta T, Kawahara J, Uno T, Iwata M, Kobayashi M.
    Mol Cell Biol; 2001 Aug 24; 21(15):5050-62. PubMed ID: 11438661
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  • 16. Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation.
    Hançer NJ, Qiu W, Cherella C, Li Y, Copps KD, White MF.
    J Biol Chem; 2014 May 02; 289(18):12467-84. PubMed ID: 24652289
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  • 17. Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.
    Mehdi MZ, Vardatsikos G, Pandey SK, Srivastava AK.
    Biochemistry; 2006 Sep 26; 45(38):11605-15. PubMed ID: 16981720
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  • 18. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4640-5. PubMed ID: 11287630
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  • 19. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
    Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G.
    Endocrinology; 2004 Jun 10; 145(6):2845-57. PubMed ID: 15001544
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  • 20. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
    Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP.
    J Biol Chem; 2005 Jun 03; 280(22):21622-8. PubMed ID: 15799971
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