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118 related items for PubMed ID: 10508267

  • 1. Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice.
    Mee PJ, Turner M, Basson MA, Costello PS, Zamoyska R, Tybulewicz VL.
    Eur J Immunol; 1999 Sep; 29(9):2923-33. PubMed ID: 10508267
    [Abstract] [Full Text] [Related]

  • 2. CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.
    Byth KF, Conroy LA, Howlett S, Smith AJ, May J, Alexander DR, Holmes N.
    J Exp Med; 1996 Apr 01; 183(4):1707-18. PubMed ID: 8666928
    [Abstract] [Full Text] [Related]

  • 3. Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.
    Falahati R, Leitenberg D.
    J Immunol; 2008 Nov 01; 181(9):6082-91. PubMed ID: 18941197
    [Abstract] [Full Text] [Related]

  • 4. Thymic selection generates T cells expressing self-reactive TCRs in the absence of CD45.
    Trop S, Charron J, Arguin C, Lesage S, Hugo P.
    J Immunol; 2000 Sep 15; 165(6):3073-9. PubMed ID: 10975818
    [Abstract] [Full Text] [Related]

  • 5. CD45RA and CD45RBhigh expression induced by thymic selection events.
    Wallace VA, Fung-Leung WP, Timms E, Gray D, Kishihara K, Loh DY, Penninger J, Mak TW.
    J Exp Med; 1992 Dec 01; 176(6):1657-63. PubMed ID: 1460424
    [Abstract] [Full Text] [Related]

  • 6. Alterations in the level of CD45 surface expression affect the outcome of thymic selection.
    Wallace VA, Penninger JM, Kishihara K, Timms E, Shahinian A, Pircher H, Kündig TM, Ohashi PS, Mak TW.
    J Immunol; 1997 Apr 01; 158(7):3205-14. PubMed ID: 9120275
    [Abstract] [Full Text] [Related]

  • 7. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.
    Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A.
    Immunity; 2010 Mar 26; 32(3):342-54. PubMed ID: 20346773
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis mediated through CD45 is independent of its phosphatase activity and association with leukocyte phosphatase-associated phosphoprotein.
    Fortin M, Steff AM, Felberg J, Ding I, Schraven B, Johnson P, Hugo P.
    J Immunol; 2002 Jun 15; 168(12):6084-9. PubMed ID: 12055218
    [Abstract] [Full Text] [Related]

  • 9. Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development.
    Falahati R, Leitenberg D.
    J Immunol; 2007 Feb 15; 178(4):2056-64. PubMed ID: 17277109
    [Abstract] [Full Text] [Related]

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  • 11. TCR signaling thresholds regulating T cell development and activation are dependent upon SHP-1.
    Johnson KG, LeRoy FG, Borysiewicz LK, Matthews RJ.
    J Immunol; 1999 Apr 01; 162(7):3802-13. PubMed ID: 10201897
    [Abstract] [Full Text] [Related]

  • 12. Defective depletion of CD45-null thymocytes by the Staphylococcus aureus enterotoxin B superantigen.
    Conroy LA, Byth KF, Howlett S, Holmes N, Alexander DR.
    Immunol Lett; 1996 Dec 01; 54(2-3):119-22. PubMed ID: 9052865
    [Abstract] [Full Text] [Related]

  • 13. The constitutive tyrosine phosphorylation of CD3zeta results from TCR-MHC interactions that are independent of thymic selection.
    Becker AM, DeFord-Watts LM, Wuelfing C, van Oers NS.
    J Immunol; 2007 Apr 01; 178(7):4120-8. PubMed ID: 17371967
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  • 14. Limiting TCR expression leads to quantitative but not qualitative changes in thymic selection.
    Dave VP, Allman D, Wiest DL, Kappes DJ.
    J Immunol; 1999 May 15; 162(10):5764-74. PubMed ID: 10229809
    [Abstract] [Full Text] [Related]

  • 15. Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection.
    Ong CJ, Chui D, Teh HS, Marth JD.
    J Immunol; 1994 Apr 15; 152(8):3793-805. PubMed ID: 8144949
    [Abstract] [Full Text] [Related]

  • 16. Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction.
    Schönrich G, Strauss G, Müller KP, Dustin L, Loh DY, Auphan N, Schmitt-Verhulst AM, Arnold B, Hämmerling GJ.
    J Immunol; 1993 Oct 15; 151(8):4098-105. PubMed ID: 8104994
    [Abstract] [Full Text] [Related]

  • 17. CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation.
    Turka LA, Kanner SB, Schieven GL, Thompson CB, Ledbetter JA.
    Eur J Immunol; 1992 Feb 15; 22(2):551-7. PubMed ID: 1371471
    [Abstract] [Full Text] [Related]

  • 18. Surface expression of a heterologous phosphatase complements CD45 deficiency in a T cell clone.
    Motto DG, Musci MA, Koretzky GA.
    J Exp Med; 1994 Oct 01; 180(4):1359-66. PubMed ID: 7931069
    [Abstract] [Full Text] [Related]

  • 19. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45.
    Kozieradzki I, Kündig T, Kishihara K, Ong CJ, Chiu D, Wallace VA, Kawai K, Timms E, Ionescu J, Ohashi P, Marth JD, Mak TW, Penninger JM.
    J Immunol; 1997 Apr 01; 158(7):3130-9. PubMed ID: 9120266
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