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Journal Abstract Search

384 related items for PubMed ID: 10514291

  • 1.
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  • 2. Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes.
    Quaglia W, Pigini M, Piergentili A, Giannella M, Marucci G, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 1999 Jul 29; 42(15):2961-8. PubMed ID: 10425105
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  • 3. Structure-activity relationships in 1,4-benzodioxan-related compounds. 7. Selectivity of 4-phenylchroman analogues for alpha(1)-adrenoreceptor subtypes.
    Quaglia W, Pigini M, Piergentili A, Giannella M, Gentili F, Marucci G, Carrieri A, Carotti A, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 2002 Apr 11; 45(8):1633-43. PubMed ID: 11931617
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  • 5. Synthesis, absolute configuration, and biological profile of the enantiomers of trans-[2-(2,6-dimethoxyphenoxy)ethyl] [(3-p-tolyl-2,3-dihydro-1,4-benzodioxin-2-yl)methyl]amine (mephendioxan), a potent competitive alpha 1A-adrenoreceptor antagonist.
    Quaglia W, Pigini M, Tayebati SK, Piergentili A, Giannella M, Leonardi A, Taddei C, Melchiorre C.
    J Med Chem; 1996 May 24; 39(11):2253-8. PubMed ID: 8667368
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  • 6. Design, synthesis, and biological activity of prazosin-related antagonists. Role of the piperazine and furan units of prazosin on the selectivity for alpha1-adrenoreceptor subtypes.
    Bolognesi ML, Budriesi R, Chiarini A, Poggesi E, Leonardi A, Melchiorre C.
    J Med Chem; 1998 Nov 19; 41(24):4844-53. PubMed ID: 9822553
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  • 13. Evaluation of the pharmacological selectivity profile of alpha 1 adrenoceptor antagonists at prostatic alpha 1 adrenoceptors: binding, functional and in vivo studies.
    Kenny BA, Miller AM, Williamson IJ, O'Connell J, Chalmers DH, Naylor AM.
    Br J Pharmacol; 1996 Jun 19; 118(4):871-8. PubMed ID: 8799556
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  • 14. Evidence for a functional alpha 1A- (alpha 1C-) adrenoceptor mediating contraction of the rat epididymal vas deferens and an alpha 1B-adrenoceptor mediating contraction of the rat spleen.
    Burt RP, Chapple CR, Marshall I.
    Br J Pharmacol; 1995 Jun 19; 115(3):467-75. PubMed ID: 7582458
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  • 15. trans-4-[4-(Methoxyphenyl)cyclohexyl]-1-arylpiperazines: a new class of potent and selective 5-HT(1A) receptor ligands as conformationally constrained analogues of 4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]-1-arylpiperazines.
    Perrone R, Berardi F, Colabufo NA, Leopoldo M, Lacivita E, Tortorella V, Leonardi A, Poggesi E, Testa R.
    J Med Chem; 2001 Dec 06; 44(25):4431-42. PubMed ID: 11728188
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  • 16. Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
    Quaglia W, Piergentili A, Del Bello F, Farande Y, Giannella M, Pigini M, Rafaiani G, Carrieri A, Amantini C, Lucciarini R, Santoni G, Poggesi E, Leonardi A.
    J Med Chem; 2008 Oct 23; 51(20):6359-70. PubMed ID: 18817363
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  • 17. Search for alpha 1-adrenoceptor subtypes selective antagonists: design, synthesis and biological activity of cystazosin, an alpha 1D-adrenoceptor antagonist.
    Minarini A, Budriesi R, Chiarini A, Leonardi A, Melchiorre C.
    Bioorg Med Chem Lett; 1998 Jun 02; 8(11):1353-8. PubMed ID: 9871765
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  • 18. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L, Pérez-Silanes S, Oficialdegui AM, Martínez-Esparza J, Del Castillo JC, Mourelle M, Langer T, Guccione S, Donzella G, Krovat EM, Poptodorov K, Lasheras B, Ballaz S, Hervías I, Tordera R, Del Río J, Monge A.
    J Med Chem; 2002 Sep 12; 45(19):4128-39. PubMed ID: 12213056
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  • 19. Structure-affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of alpha 1 antagonist WB-4101.
    Bolchi C, Catalano P, Fumagalli L, Gobbi M, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E.
    Bioorg Med Chem; 2004 Sep 15; 12(18):4937-51. PubMed ID: 15336273
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  • 20. N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents.
    Birch AM, Bradley PA, Gill JC, Kerrigan F, Needham PL.
    J Med Chem; 1999 Aug 26; 42(17):3342-55. PubMed ID: 10464021
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