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338 related items for PubMed ID: 10525406

  • 1. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
    Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D.
    J Mol Biol; 1999 Oct 01; 292(4):797-817. PubMed ID: 10525406
    [Abstract] [Full Text] [Related]

  • 2. Doppel-induced cerebellar degeneration in transgenic mice.
    Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P.
    Proc Natl Acad Sci U S A; 2001 Dec 18; 98(26):15288-93. PubMed ID: 11734625
    [Abstract] [Full Text] [Related]

  • 3. Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain.
    Rossi D, Cozzio A, Flechsig E, Klein MA, Rülicke T, Aguzzi A, Weissmann C.
    EMBO J; 2001 Feb 15; 20(4):694-702. PubMed ID: 11179214
    [Abstract] [Full Text] [Related]

  • 4. Tissue- and cell type-specific modification of prion protein (PrP)-like protein Doppel, which affects PrP endoproteolysis.
    Sakudo A, Onodera T.
    Biochem Biophys Res Commun; 2011 Jan 07; 404(1):523-7. PubMed ID: 21144827
    [Abstract] [Full Text] [Related]

  • 5. Genomic characterization of the human prion protein (PrP) gene locus.
    Makrinou E, Collinge J, Antoniou M.
    Mamm Genome; 2002 Dec 07; 13(12):696-703. PubMed ID: 12514748
    [Abstract] [Full Text] [Related]

  • 6. The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis.
    Mastrangelo P, Westaway D.
    Gene; 2001 Sep 05; 275(1):1-18. PubMed ID: 11574147
    [Abstract] [Full Text] [Related]

  • 7. BCL-2 counteracts Doppel-induced apoptosis of prion-protein-deficient Purkinje cells in the Ngsk Prnp(0/0) mouse.
    Heitz S, Gautheron V, Lutz Y, Rodeau JL, Zanjani HS, Sugihara I, Bombarde G, Richard F, Fuchs JP, Vogel MW, Mariani J, Bailly Y.
    Dev Neurobiol; 2008 Feb 15; 68(3):332-48. PubMed ID: 18085563
    [Abstract] [Full Text] [Related]

  • 8. The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression.
    Tranulis MA, Espenes A, Comincini S, Skretting G, Harbitz I.
    Mamm Genome; 2001 May 15; 12(5):376-9. PubMed ID: 11331946
    [Abstract] [Full Text] [Related]

  • 9. Japanese scrapie cases.
    Onodera T, Saeki K.
    Jpn J Infect Dis; 2000 Apr 15; 53(2):56-61. PubMed ID: 10871915
    [Abstract] [Full Text] [Related]

  • 10. Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders.
    Schröder B, Franz B, Hempfling P, Selbert M, Jürgens T, Kretzschmar HA, Bodemer M, Poser S, Zerr I.
    Hum Genet; 2001 Sep 15; 109(3):319-25. PubMed ID: 11702213
    [Abstract] [Full Text] [Related]

  • 11. Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
    Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D.
    J Biol Chem; 2000 Sep 01; 275(35):26834-41. PubMed ID: 10842180
    [Abstract] [Full Text] [Related]

  • 12. Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature.
    Al Bersaoui R, Robert I, Lutz Y, Blanc F, Sommermeyer-Leroux G, Shibaguchi H, Aunis D, Fuchs JP.
    FEBS Lett; 2005 May 09; 579(12):2715-21. PubMed ID: 15862314
    [Abstract] [Full Text] [Related]

  • 13. Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells.
    Comincini S, Chiarelli LR, Zelini P, Del Vecchio I, Azzalin A, Arias A, Ferrara V, Rognoni P, Dipoto A, Nano R, Valentini G, Ferretti L.
    Oncol Rep; 2006 Dec 09; 16(6):1325-32. PubMed ID: 17089057
    [Abstract] [Full Text] [Related]

  • 14. Altered expression of type 1 inositol 1,4,5-trisphosphate receptor in the Ngsk Prnp deficient mice.
    Lee HP, Choi JK, Shin HY, Jeon YC, Jeong BH, Lee HG, Kim JI, Choi EK, Carp RI, Kim YS.
    Neuroscience; 2010 May 19; 167(3):799-808. PubMed ID: 20219645
    [Abstract] [Full Text] [Related]

  • 15. Cell-autonomous PrP-Doppel interaction regulates apoptosis in PrP gene-deficient neuronal cells.
    Sakudo A, Lee DC, Nakamura I, Taniuchi Y, Saeki K, Matsumoto Y, Itohara S, Ikuta K, Onodera T.
    Biochem Biophys Res Commun; 2005 Jul 29; 333(2):448-54. PubMed ID: 15950943
    [Abstract] [Full Text] [Related]

  • 16. Deletion of N-terminal residues 23-88 from prion protein (PrP) abrogates the potential to rescue PrP-deficient mice from PrP-like protein/doppel-induced Neurodegeneration.
    Atarashi R, Nishida N, Shigematsu K, Goto S, Kondo T, Sakaguchi S, Katamine S.
    J Biol Chem; 2003 Aug 01; 278(31):28944-9. PubMed ID: 12759361
    [Abstract] [Full Text] [Related]

  • 17. Newly established in vitro system with fluorescent proteins shows that abnormal expression of downstream prion protein-like protein in mice is probably due to functional disconnection between splicing and 3' formation of prion protein pre-mRNA.
    Yoshikawa D, Kopacek J, Yamaguchi N, Ishibashi D, Yamanaka H, Yamaguchi Y, Katamine S, Sakaguchi S.
    Gene; 2007 Jan 15; 386(1-2):139-46. PubMed ID: 17034959
    [Abstract] [Full Text] [Related]

  • 18. Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration.
    Li A, Sakaguchi S, Shigematsu K, Atarashi R, Roy BC, Nakaoke R, Arima K, Okimura N, Kopacek J, Katamine S.
    Am J Pathol; 2000 Nov 15; 157(5):1447-52. PubMed ID: 11073804
    [Abstract] [Full Text] [Related]

  • 19. Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia.
    Flechsig E, Hegyi I, Leimeroth R, Zuniga A, Rossi D, Cozzio A, Schwarz P, Rülicke T, Götz J, Aguzzi A, Weissmann C.
    EMBO J; 2003 Jun 16; 22(12):3095-101. PubMed ID: 12805223
    [Abstract] [Full Text] [Related]

  • 20. Prion and doppel proteins bind to granule cells of the cerebellum.
    Legname G, Nelken P, Guan Z, Kanyo ZF, DeArmond SJ, Prusiner SB.
    Proc Natl Acad Sci U S A; 2002 Dec 10; 99(25):16285-90. PubMed ID: 12446843
    [Abstract] [Full Text] [Related]

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