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Journal Abstract Search

128 related items for PubMed ID: 10527522

  • 1. A nonradioisotope biomedical assay for intact oligonucleotide and its chain-shortened metabolites used for determination of exposure and elimination half-life of antisense drugs in tissue.
    Geary RS, Matson J, Levin AA.
    Anal Biochem; 1999 Oct 15; 274(2):241-8. PubMed ID: 10527522
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  • 2. Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression.
    Geary RS, Leeds JM, Fitchett J, Burckin T, Truong L, Spainhour C, Creek M, Levin AA.
    Drug Metab Dispos; 1997 Nov 15; 25(11):1272-81. PubMed ID: 9351904
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  • 3. Antiviral activity and ocular kinetics of antisense oligonucleotides designed to inhibit CMV replication.
    Henry SP, Miner RC, Drew WL, Fitchett J, York-Defalco C, Rapp LM, Levin AA.
    Invest Ophthalmol Vis Sci; 2001 Oct 15; 42(11):2646-51. PubMed ID: 11581212
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  • 4. Pharmacokinetic properties of several novel oligonucleotide analogs in mice.
    Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornbrust D, Manoharan M, Sasmor HM, Schleich T, Tivel KL, Griffey RH.
    J Pharmacol Exp Ther; 1996 May 15; 277(2):923-37. PubMed ID: 8627575
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  • 11. Pharmacokinetics, tissue distribution, and stability of antisense oligodeoxynucleotide phosphorothioate ISIS 3466 in mice.
    Saijo Y, Perlaky L, Wang H, Busch H.
    Oncol Res; 1994 May 15; 6(6):243-9. PubMed ID: 7865900
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  • 14. In vivo stability, disposition and metabolism of a "hybrid" oligonucleotide phosphorothioate in rats.
    Zhang R, Lu Z, Zhao H, Zhang X, Diasio RB, Habus I, Jiang Z, Iyer RP, Yu D, Agrawal S.
    Biochem Pharmacol; 1995 Aug 08; 50(4):545-56. PubMed ID: 7646561
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  • 15. Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects.
    Zhang R, Yan J, Shahinian HK, Amin G, Lu Z, Liu T, Saag MS, Jiang Z, Temsamani J, Martin RR.
    Clin Pharmacol Ther; 1995 Jul 08; 58(1):44-53. PubMed ID: 7628182
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  • 16. Use of capillary electrophoresis methods to characterize the pharmacokinetics of antisense drugs.
    Chen SH, Gallo JM.
    Electrophoresis; 1998 Nov 08; 19(16-17):2861-9. PubMed ID: 9870381
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