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Journal Abstract Search

323 related items for PubMed ID: 10534312

  • 1. Prediction of human liver microsomal oxidations of 7-ethoxycoumarin and chlorzoxazone with kinetic parameters of recombinant cytochrome P-450 enzymes.
    Shimada T, Tsumura F, Yamazaki H.
    Drug Metab Dispos; 1999 Nov; 27(11):1274-80. PubMed ID: 10534312
    [Abstract] [Full Text] [Related]

  • 2. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ, Yokoyama H, Chiba K, Wanwimolruk S, Ishizaki T.
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [Abstract] [Full Text] [Related]

  • 3. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
    Hanioka N, Yamamoto M, Iwabu H, Jinno H, Tanaka-Kagawa T, Naito S, Shimizu T, Masuda K, Katsu T, Narimatsu S.
    Life Sci; 2007 Oct 27; 81(19-20):1436-45. PubMed ID: 17935737
    [Abstract] [Full Text] [Related]

  • 4. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 27; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

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  • 6. Inhibitory effects of azelastine and its metabolites on drug oxidation catalyzed by human cytochrome P-450 enzymes.
    Nakajima M, Ohyama K, Nakamura S, Shimada N, Yamazaki H, Yokoi T.
    Drug Metab Dispos; 1999 Jul 27; 27(7):792-7. PubMed ID: 10383922
    [Abstract] [Full Text] [Related]

  • 7. Reappraisal of human CYP isoforms involved in imipramine N-demethylation and 2-hydroxylation: a study using microsomes obtained from putative extensive and poor metabolizers of S-mephenytoin and eleven recombinant human CYPs.
    Koyama E, Chiba K, Tani M, Ishizaki T.
    J Pharmacol Exp Ther; 1997 Jun 27; 281(3):1199-210. PubMed ID: 9190854
    [Abstract] [Full Text] [Related]

  • 8. 7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.
    Yamazaki H, Inoue K, Mimura M, Oda Y, Guengerich FP, Shimada T.
    Biochem Pharmacol; 1996 Feb 09; 51(3):313-9. PubMed ID: 8573198
    [Abstract] [Full Text] [Related]

  • 9. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H, Shimada T.
    Xenobiotica; 1999 Mar 09; 29(3):231-41. PubMed ID: 10219964
    [Abstract] [Full Text] [Related]

  • 10. Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: ratios of accessory proteins as sources of discrepancies between the approaches.
    Venkatakrishnan K, von Moltke LL, Court MH, Harmatz JS, Crespi CL, Greenblatt DJ.
    Drug Metab Dispos; 2000 Dec 09; 28(12):1493-504. PubMed ID: 11095589
    [Abstract] [Full Text] [Related]

  • 11. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T, Yamazaki H, Mimura M, Wakamiya N, Ueng YF, Guengerich FP, Inui Y.
    Drug Metab Dispos; 1996 May 09; 24(5):515-22. PubMed ID: 8723730
    [Abstract] [Full Text] [Related]

  • 12. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.
    Chang TK, Weber GF, Crespi CL, Waxman DJ.
    Cancer Res; 1993 Dec 01; 53(23):5629-37. PubMed ID: 8242617
    [Abstract] [Full Text] [Related]

  • 13. Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
    Yun CH, Shimada T, Guengerich FP.
    Cancer Res; 1992 Apr 01; 52(7):1868-74. PubMed ID: 1551116
    [Abstract] [Full Text] [Related]

  • 14. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S, Paxton JW, Tingle MD, Kestell P.
    Drug Metab Dispos; 2000 Dec 01; 28(12):1449-56. PubMed ID: 11095582
    [Abstract] [Full Text] [Related]

  • 15. A significant role of human cytochrome P450 2C8 in amiodarone N-deethylation: an approach to predict the contribution with relative activity factor.
    Ohyama K, Nakajima M, Nakamura S, Shimada N, Yamazaki H, Yokoi T.
    Drug Metab Dispos; 2000 Nov 01; 28(11):1303-10. PubMed ID: 11038157
    [Abstract] [Full Text] [Related]

  • 16. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
    Yamazaki H, Shaw PM, Guengerich FP, Shimada T.
    Chem Res Toxicol; 1998 Jun 01; 11(6):659-65. PubMed ID: 9625734
    [Abstract] [Full Text] [Related]

  • 17. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
    Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.
    Eur Neuropsychopharmacol; 2004 May 01; 14(3):199-208. PubMed ID: 15056479
    [Abstract] [Full Text] [Related]

  • 18. The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes.
    Yao HT, Chang YW, Lan SJ, Yeh TK.
    Food Chem Toxicol; 2008 Feb 01; 46(2):645-53. PubMed ID: 17950511
    [Abstract] [Full Text] [Related]

  • 19. Studies on the cytochrome P450 (CYP)-mediated metabolic properties of miocamycin: evaluation of the possibility of a metabolic intermediate complex formation with CYP, and identification of the human CYP isoforms.
    Kasahara M, Suzuki H, Komiya I.
    Drug Metab Dispos; 2000 Apr 01; 28(4):409-17. PubMed ID: 10725309
    [Abstract] [Full Text] [Related]

  • 20. Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.
    Tassaneeyakul W, Birkett DJ, Veronese ME, McManus ME, Tukey RH, Quattrochi LC, Gelboin HV, Miners JO.
    J Pharmacol Exp Ther; 1993 Apr 01; 265(1):401-7. PubMed ID: 8474022
    [Abstract] [Full Text] [Related]

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