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124 related items for PubMed ID: 10535746

  • 1. Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.
    Park LC, Gibson GE, Bunik V, Cooper AJ.
    Biochem Pharmacol; 1999 Nov 15; 58(10):1557-65. PubMed ID: 10535746
    [Abstract] [Full Text] [Related]

  • 2. Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism.
    Cooper AJ, Bruschi SA, Anders MW.
    Biochem Pharmacol; 2002 Aug 15; 64(4):553-64. PubMed ID: 12167474
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.
    James EA, Gygi SP, Adams ML, Pierce RH, Fausto N, Aebersold RH, Nelson SD, Bruschi SA.
    Biochemistry; 2002 May 28; 41(21):6789-97. PubMed ID: 12022883
    [Abstract] [Full Text] [Related]

  • 4. Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation.
    Cooper AJ, Bruschi SA, Conway M, Hutson SM.
    Biochem Pharmacol; 2003 Jan 15; 65(2):181-92. PubMed ID: 12504794
    [Abstract] [Full Text] [Related]

  • 5. Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells.
    Zhang L, Cooper AJ, Krasnikov BF, Xu H, Bubber P, Pinto JT, Gibson GE, Hanigan MH.
    Biochemistry; 2006 Jul 25; 45(29):8959-71. PubMed ID: 16846239
    [Abstract] [Full Text] [Related]

  • 6. L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?
    Cooper AJ, Krasnikov BF, Okuno E, Jeitner TM.
    Biochem J; 2003 Nov 15; 376(Pt 1):169-78. PubMed ID: 12859250
    [Abstract] [Full Text] [Related]

  • 7. Co-purification of mitochondrial HSP70 and mature protein disulfide isomerase with a functional rat kidney high-M(r) cysteine S-conjugate beta-lyase.
    Cooper AJ, Wang J, Gartner CA, Bruschi SA.
    Biochem Pharmacol; 2001 Nov 15; 62(10):1345-53. PubMed ID: 11709194
    [Abstract] [Full Text] [Related]

  • 8. Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions.
    Cooper AJ, Bruschi SA, Iriarte A, Martinez-Carrion M.
    Biochem J; 2002 Nov 15; 368(Pt 1):253-61. PubMed ID: 12137566
    [Abstract] [Full Text] [Related]

  • 9. The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities.
    Lock EA, Schnellmann RG.
    Toxicol Appl Pharmacol; 1990 Jun 01; 104(1):180-90. PubMed ID: 2360207
    [Abstract] [Full Text] [Related]

  • 10. Inactivation of brain and kidney aspartate aminotransferases by S-(1,2,-dichlorovinyl)-L-cysteine and by S-(1,1,2,2,-tetrafluoroethyl)-L-cysteine.
    Kato Y, Asano Y, Cooper AJ.
    Dev Neurosci; 1996 Jun 01; 18(5-6):505-14. PubMed ID: 8940625
    [Abstract] [Full Text] [Related]

  • 11. Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death.
    Bruschi SA, Lindsay JG, Crabb JW.
    Proc Natl Acad Sci U S A; 1998 Nov 10; 95(23):13413-8. PubMed ID: 9811814
    [Abstract] [Full Text] [Related]

  • 12. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
    McGoldrick TA, Lock EA, Rodilla V, Hawksworth GM.
    Arch Toxicol; 2003 Jul 10; 77(7):365-70. PubMed ID: 12700887
    [Abstract] [Full Text] [Related]

  • 13. Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity?
    Cooper AJ, Pinto JT.
    Biochem Pharmacol; 2005 Jan 15; 69(2):209-20. PubMed ID: 15627473
    [Abstract] [Full Text] [Related]

  • 14. Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents.
    Cooper AJ, Krasnikov BF, Niatsetskaya ZV, Pinto JT, Callery PS, Villar MT, Artigues A, Bruschi SA.
    Amino Acids; 2011 Jun 15; 41(1):7-27. PubMed ID: 20306345
    [Abstract] [Full Text] [Related]

  • 15. Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors.
    Lai JC, Cooper AJ.
    J Neurochem; 1986 Nov 15; 47(5):1376-86. PubMed ID: 3760866
    [Abstract] [Full Text] [Related]

  • 16. Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites.
    Hayden PJ, Welsh CJ, Yang Y, Schaefer WH, Ward AJ, Stevens JL.
    Chem Res Toxicol; 1992 Nov 15; 5(2):232-7. PubMed ID: 1643252
    [Abstract] [Full Text] [Related]

  • 17. The nephrotoxicity and hepatotoxicity of 1,1,2,2-tetrafluoroethyl-L-cysteine in the rat.
    Lock EA, Ishmael J.
    Arch Toxicol; 1998 May 15; 72(6):347-54. PubMed ID: 9657282
    [Abstract] [Full Text] [Related]

  • 18. Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
    Elfarra AA, Lash LH, Anders MW.
    Mol Pharmacol; 1987 Feb 15; 31(2):208-12. PubMed ID: 3807895
    [Abstract] [Full Text] [Related]

  • 19. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product compound A in human, nonhuman primate, and rat kidney cytosol and mitochondria.
    Iyer RA, Anders MW.
    Anesthesiology; 1996 Dec 15; 85(6):1454-61. PubMed ID: 8968194
    [Abstract] [Full Text] [Related]

  • 20. The effects of haloalkene cysteine conjugates on cytosolic free calcium levels in suspensions of rat renal proximal tubules.
    Groves CE, Lock EA, Schnellmann RG.
    J Biochem Toxicol; 1990 Dec 15; 5(3):187-92. PubMed ID: 2283670
    [Abstract] [Full Text] [Related]

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