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Journal Abstract Search

512 related items for PubMed ID: 10535940

  • 1. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
    Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A.
    Proc Natl Acad Sci U S A; 1999 Oct 26; 96(22):12436-41. PubMed ID: 10535940
    [Abstract] [Full Text] [Related]

  • 2. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
    Pause A, Lee S, Worrell RA, Chen DY, Burgess WH, Linehan WM, Klausner RD.
    Proc Natl Acad Sci U S A; 1997 Mar 18; 94(6):2156-61. PubMed ID: 9122164
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  • 4. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.
    Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD.
    Proc Natl Acad Sci U S A; 1999 Aug 17; 96(17):9533-8. PubMed ID: 10449727
    [Abstract] [Full Text] [Related]

  • 5. The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity.
    Lisztwan J, Imbert G, Wirbelauer C, Gstaiger M, Krek W.
    Genes Dev; 1999 Jul 15; 13(14):1822-33. PubMed ID: 10421634
    [Abstract] [Full Text] [Related]

  • 6. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ, Ohh M, Moslehi J, Kondo K, Kaelin WG, Welch WJ.
    Mol Cell Biol; 2002 Mar 15; 22(6):1947-60. PubMed ID: 11865071
    [Abstract] [Full Text] [Related]

  • 7. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
    [Abstract] [Full Text] [Related]

  • 8. Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products.
    Schoenfeld AR, Davidowitz EJ, Burk RD.
    Proc Natl Acad Sci U S A; 2000 Jul 18; 97(15):8507-12. PubMed ID: 10900011
    [Abstract] [Full Text] [Related]

  • 9. Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity.
    Aso T, Yamazaki K, Aigaki T, Kitajima S.
    Biochem Biophys Res Commun; 2000 Sep 16; 276(1):355-61. PubMed ID: 11006129
    [Abstract] [Full Text] [Related]

  • 10. Identification of Elongin C and Skp1 sequences that determine Cullin selection.
    Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW.
    J Biol Chem; 2004 Oct 08; 279(41):43019-26. PubMed ID: 15280393
    [Abstract] [Full Text] [Related]

  • 11. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
    Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER.
    Hum Mol Genet; 2001 May 01; 10(10):1029-38. PubMed ID: 11331613
    [Abstract] [Full Text] [Related]

  • 12. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
    Kamura T, Burian D, Yan Q, Schmidt SL, Lane WS, Querido E, Branton PE, Shilatifard A, Conaway RC, Conaway JW.
    J Biol Chem; 2001 Aug 10; 276(32):29748-53. PubMed ID: 11384984
    [Abstract] [Full Text] [Related]

  • 13. The von Hippel-Lindau tumour suppressor protein: new perspectives.
    Ohh M, Kaelin WG.
    Mol Med Today; 1999 Jun 10; 5(6):257-63. PubMed ID: 10366821
    [Abstract] [Full Text] [Related]

  • 14. A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
    Kamura T, Brower CS, Conaway RC, Conaway JW.
    J Biol Chem; 2002 Aug 16; 277(33):30388-93. PubMed ID: 12048197
    [Abstract] [Full Text] [Related]

  • 15. Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.
    Li Z, Na X, Wang D, Schoen SR, Messing EM, Wu G.
    J Biol Chem; 2002 Feb 15; 277(7):4656-62. PubMed ID: 11739384
    [Abstract] [Full Text] [Related]

  • 16. The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.
    Okuda H, Saitoh K, Hirai S, Iwai K, Takaki Y, Baba M, Minato N, Ohno S, Shuin T.
    J Biol Chem; 2001 Nov 23; 276(47):43611-7. PubMed ID: 11574546
    [Abstract] [Full Text] [Related]

  • 17. Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function.
    Liakopoulos D, Büsgen T, Brychzy A, Jentsch S, Pause A.
    Proc Natl Acad Sci U S A; 1999 May 11; 96(10):5510-5. PubMed ID: 10318914
    [Abstract] [Full Text] [Related]

  • 18. Role of exon 2-encoded beta -domain of the von Hippel-Lindau tumor suppressor protein.
    Bonicalzi ME, Groulx I, de Paulsen N, Lee S.
    J Biol Chem; 2001 Jan 12; 276(2):1407-16. PubMed ID: 11024059
    [Abstract] [Full Text] [Related]

  • 19. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
    Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW.
    Science; 1999 Apr 23; 284(5414):657-61. PubMed ID: 10213691
    [Abstract] [Full Text] [Related]

  • 20. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
    Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW.
    Genes Dev; 1999 Nov 15; 13(22):2928-33. PubMed ID: 10579999
    [Abstract] [Full Text] [Related]

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