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238 related items for PubMed ID: 10537193

  • 1. Multiple amino acid substitutions in lanosterol 14alpha-demethylase contribute to azole resistance in Candida albicans.
    Favre B, Didmon M, Ryder NS.
    Microbiology (Reading); 1999 Oct; 145 ( Pt 10)():2715-25. PubMed ID: 10537193
    [Abstract] [Full Text] [Related]

  • 2. Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents.
    Sanglard D, Ischer F, Koymans L, Bille J.
    Antimicrob Agents Chemother; 1998 Feb; 42(2):241-53. PubMed ID: 9527767
    [Abstract] [Full Text] [Related]

  • 3. Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.
    Marichal P, Koymans L, Willemsens S, Bellens D, Verhasselt P, Luyten W, Borgers M, Ramaekers FCS, Odds FC, Vanden Bossche H.
    Microbiology (Reading); 1999 Oct; 145 ( Pt 10)():2701-2713. PubMed ID: 10537192
    [Abstract] [Full Text] [Related]

  • 4. Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients.
    Perea S, López-Ribot JL, Kirkpatrick WR, McAtee RK, Santillán RA, Martínez M, Calabrese D, Sanglard D, Patterson TF.
    Antimicrob Agents Chemother; 2001 Oct; 45(10):2676-84. PubMed ID: 11557454
    [Abstract] [Full Text] [Related]

  • 5. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.
    Sanglard D, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.
    Antimicrob Agents Chemother; 1995 Nov; 39(11):2378-86. PubMed ID: 8585712
    [Abstract] [Full Text] [Related]

  • 6. Y132H substitution in Candida albicans sterol 14alpha-demethylase confers fluconazole resistance by preventing binding to haem.
    Kelly SL, Lamb DC, Kelly DE.
    FEMS Microbiol Lett; 1999 Nov 15; 180(2):171-5. PubMed ID: 10556708
    [Abstract] [Full Text] [Related]

  • 7. The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity.
    Lamb DC, Kelly DE, Schunck WH, Shyadehi AZ, Akhtar M, Lowe DJ, Baldwin BC, Kelly SL.
    J Biol Chem; 1997 Feb 28; 272(9):5682-8. PubMed ID: 9038178
    [Abstract] [Full Text] [Related]

  • 8. The G464S amino acid substitution in Candida albicans sterol 14alpha-demethylase causes fluconazole resistance in the clinic through reduced affinity.
    Kelly SL, Lamb DC, Loeffler J, Einsele H, Kelly DE.
    Biochem Biophys Res Commun; 1999 Aug 19; 262(1):174-9. PubMed ID: 10448088
    [Abstract] [Full Text] [Related]

  • 9. Genetic analysis of azole resistance in the Darlington strain of Candida albicans.
    Kakeya H, Miyazaki Y, Miyazaki H, Nyswaner K, Grimberg B, Bennett JE.
    Antimicrob Agents Chemother; 2000 Nov 19; 44(11):2985-90. PubMed ID: 11036010
    [Abstract] [Full Text] [Related]

  • 10. The amino acid substitution N136Y in Candida albicans sterol 14alpha-demethylase is involved in fluconazole resistance.
    Alvarez-Rueda N, Fleury A, Logé C, Pagniez F, Robert E, Morio F, Le Pape P.
    Med Mycol; 2016 Oct 01; 54(7):764-775. PubMed ID: 27143634
    [Abstract] [Full Text] [Related]

  • 11. A newly identified amino acid substitution T123I in the 14α-demethylase (Erg11p) of Candida albicans confers azole resistance.
    Wu Y, Gao N, Li C, Gao J, Ying C.
    FEMS Yeast Res; 2017 May 01; 17(3):. PubMed ID: 28334124
    [Abstract] [Full Text] [Related]

  • 12. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
    Sheng C, Zhang W, Zhang M, Song Y, Ji H, Zhu J, Yao J, Yu J, Yang S, Zhou Y, Zhu J, Lu J.
    J Biomol Struct Dyn; 2004 Aug 01; 22(1):91-9. PubMed ID: 15214809
    [Abstract] [Full Text] [Related]

  • 13. Nucleotide substitutions in the Candida albicans ERG11 gene of azole-susceptible and azole-resistant clinical isolates.
    Strzelczyk JK, Slemp-Migiel A, Rother M, Gołąbek K, Wiczkowski A.
    Acta Biochim Pol; 2013 Aug 01; 60(4):547-52. PubMed ID: 24340302
    [Abstract] [Full Text] [Related]

  • 14. Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene.
    Feng LJ, Wan Z, Wang XH, Li RY, Liu W.
    Chin Med J (Engl); 2010 Mar 05; 123(5):544-8. PubMed ID: 20367978
    [Abstract] [Full Text] [Related]

  • 15. Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms.
    Sanglard D, Coste AT.
    Antimicrob Agents Chemother; 2016 Jan 05; 60(1):229-38. PubMed ID: 26482310
    [Abstract] [Full Text] [Related]

  • 16. Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450.
    Asai K, Tsuchimori N, Okonogi K, Perfect JR, Gotoh O, Yoshida Y.
    Antimicrob Agents Chemother; 1999 May 05; 43(5):1163-9. PubMed ID: 10223930
    [Abstract] [Full Text] [Related]

  • 17. Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds.
    Kudo M, Ohi M, Aoyama Y, Nitahara Y, Chung SK, Yoshida Y.
    J Biochem; 2005 May 05; 137(5):625-32. PubMed ID: 15944416
    [Abstract] [Full Text] [Related]

  • 18. Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.
    Eddouzi J, Parker JE, Vale-Silva LA, Coste A, Ischer F, Kelly S, Manai M, Sanglard D.
    Antimicrob Agents Chemother; 2013 Jul 05; 57(7):3182-93. PubMed ID: 23629718
    [Abstract] [Full Text] [Related]

  • 19. Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature.
    Morio F, Loge C, Besse B, Hennequin C, Le Pape P.
    Diagn Microbiol Infect Dis; 2010 Apr 05; 66(4):373-84. PubMed ID: 20226328
    [Abstract] [Full Text] [Related]

  • 20. The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans.
    White TC.
    Antimicrob Agents Chemother; 1997 Jul 05; 41(7):1488-94. PubMed ID: 9210671
    [Abstract] [Full Text] [Related]

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