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339 related items for PubMed ID: 10543887

  • 1. Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors.
    Zacheis D, Dhar A, Lu S, Madler MM, Klucik J, Brown CW, Liu S, Clement F, Subramanian S, Weerasekare GM, Berlin KD, Gold MA, Houck JR, Fountain KR, Benbrook DM.
    J Med Chem; 1999 Oct 21; 42(21):4434-45. PubMed ID: 10543887
    [Abstract] [Full Text] [Related]

  • 2. Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.
    Sun SY, Yue P, Mao L, Dawson MI, Shroot B, Lamph WW, Heyman RA, Chandraratna RA, Shudo K, Hong WK, Lotan R.
    Clin Cancer Res; 2000 Apr 21; 6(4):1563-73. PubMed ID: 10778990
    [Abstract] [Full Text] [Related]

  • 3. Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.
    Sun SY, Yue P, Dawson MI, Shroot B, Michel S, Lamph WW, Heyman RA, Teng M, Chandraratna RA, Shudo K, Hong WK, Lotan R.
    Cancer Res; 1997 Nov 01; 57(21):4931-9. PubMed ID: 9354460
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of trans-retinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids.
    Wu Q, Dawson MI, Zheng Y, Hobbs PD, Agadir A, Jong L, Li Y, Liu R, Lin B, Zhang XK.
    Mol Cell Biol; 1997 Nov 01; 17(11):6598-608. PubMed ID: 9343423
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids.
    Dhar A, Liu S, Klucik J, Berlin KD, Madler MM, Lu S, Ivey RT, Zacheis D, Brown CW, Nelson EC, Birckbichler PJ, Benbrook DM.
    J Med Chem; 1999 Sep 09; 42(18):3602-14. PubMed ID: 10479291
    [Abstract] [Full Text] [Related]

  • 6. Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids.
    Le Q, Dawson MI, Soprano DR, Soprano KJ.
    Oncogene; 2000 Mar 09; 19(11):1457-65. PubMed ID: 10723137
    [Abstract] [Full Text] [Related]

  • 7. Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor agonists.
    Benbrook DM, Kamelle SA, Guruswamy SB, Lightfoot SA, Rutledge TL, Gould NS, Hannafon BN, Dunn ST, Berlin KD.
    Invest New Drugs; 2005 Oct 09; 23(5):417-28. PubMed ID: 16133793
    [Abstract] [Full Text] [Related]

  • 8. Effects of retinoid X receptor-selective ligands on proliferation of prostate cancer cells.
    de Vos S, Dawson MI, Holden S, Le T, Wang A, Cho SK, Chen DL, Koeffler HP.
    Prostate; 1997 Jul 01; 32(2):115-21. PubMed ID: 9215399
    [Abstract] [Full Text] [Related]

  • 9. All-trans, 13-cis and 9-cis retinoic acids induce a fully reversible growth inhibition in HNSCC cell lines: implications for in vivo retinoic acid use.
    Giannini F, Maestro R, Vukosavljevic T, Pomponi F, Boiocchi M.
    Int J Cancer; 1997 Jan 17; 70(2):194-200. PubMed ID: 9009160
    [Abstract] [Full Text] [Related]

  • 10. Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
    Fitzgerald P, Teng M, Chandraratna RA, Heyman RA, Allegretto EA.
    Cancer Res; 1997 Jul 01; 57(13):2642-50. PubMed ID: 9205071
    [Abstract] [Full Text] [Related]

  • 11. Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells.
    Haxsen V, Adam-Stitah S, Ritz E, Wagner J.
    Circ Res; 2001 Mar 30; 88(6):637-44. PubMed ID: 11282899
    [Abstract] [Full Text] [Related]

  • 12. Activation of retinoic acid receptor alpha is sufficient for full induction of retinoid responses in SK-BR-3 and T47D human breast cancer cells.
    Schneider SM, Offterdinger M, Huber H, Grunt TW.
    Cancer Res; 2000 Oct 01; 60(19):5479-87. PubMed ID: 11034091
    [Abstract] [Full Text] [Related]

  • 13. Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro.
    Kizaki M, Dawson MI, Heyman R, Elster E, Morosetti R, Pakkala S, Chen DL, Ueno H, Chao W, Morikawa M, Ikeda Y, Heber D, Pfahl M, Koeffler HP.
    Blood; 1996 Mar 01; 87(5):1977-84. PubMed ID: 8634447
    [Abstract] [Full Text] [Related]

  • 14. Suppression of squamous cell carcinoma growth and differentiation by retinoids.
    Lotan R.
    Cancer Res; 1994 Apr 01; 54(7 Suppl):1987s-1990s. PubMed ID: 8137325
    [Abstract] [Full Text] [Related]

  • 15. Abrogation of transforming growth factor-alpha/epidermal growth factor receptor autocrine signaling by an RXR-selective retinoid (LGD1069, Targretin) in head and neck cancer cell lines.
    Song JI, Lango MN, Hwang JD, Drenning SD, Zeng Q, Lamph WW, Grandis JR.
    Cancer Res; 2001 Aug 01; 61(15):5919-25. PubMed ID: 11479234
    [Abstract] [Full Text] [Related]

  • 16. Expression of retinoic acid receptor gamma correlates with retinoic acid sensitivity and metabolism in head and neck squamous cell carcinoma cell lines.
    Klaassen I, Brakenhoff RH, Smeets SJ, Snow GB, Braakhuis BJ.
    Int J Cancer; 2001 Jun 01; 92(5):661-5. PubMed ID: 11340568
    [Abstract] [Full Text] [Related]

  • 17. Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells.
    Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang Xk.
    J Biol Chem; 1999 May 28; 274(22):15360-6. PubMed ID: 10336422
    [Abstract] [Full Text] [Related]

  • 18. Reduction of both RAR and RXR levels is required to maximally alter sensitivity of CA-OV3 ovarian tumor cells to growth suppression by all-trans-retinoic acid.
    Wu S, Zhang ZP, Zhang D, Soprano DR, Soprano KJ.
    Exp Cell Res; 1997 Nov 25; 237(1):118-26. PubMed ID: 9417874
    [Abstract] [Full Text] [Related]

  • 19. Biologically active heteroarotinoids exhibiting anticancer activity and decreased toxicity.
    Benbrook DM, Madler MM, Spruce LW, Birckbichler PJ, Nelson EC, Subramanian S, Weerasekare GM, Gale JB, Patterson MK, Wang B, Wang W, Lu S, Rowland TC, DiSivestro P, Lindamood C, Hill DL, Berlin KD.
    J Med Chem; 1997 Oct 24; 40(22):3567-83. PubMed ID: 9357524
    [Abstract] [Full Text] [Related]

  • 20. Unique anti-activator protein-1 activity of retinoic acid receptor beta.
    Lin F, Xiao D, Kolluri SK, Zhang X.
    Cancer Res; 2000 Jun 15; 60(12):3271-80. PubMed ID: 10866321
    [Abstract] [Full Text] [Related]

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