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1442 related items for PubMed ID: 10543973

  • 1. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
    Chen Y, Wiesmann C, Fuh G, Li B, Christinger HW, McKay P, de Vos AM, Lowman HB.
    J Mol Biol; 1999 Nov 05; 293(4):865-81. PubMed ID: 10543973
    [Abstract] [Full Text] [Related]

  • 2. Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor.
    Pan B, Li B, Russell SJ, Tom JY, Cochran AG, Fairbrother WJ.
    J Mol Biol; 2002 Feb 22; 316(3):769-87. PubMed ID: 11866530
    [Abstract] [Full Text] [Related]

  • 3. Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen.
    Li Y, Urrutia M, Smith-Gill SJ, Mariuzza RA.
    Biochemistry; 2003 Jan 14; 42(1):11-22. PubMed ID: 12515535
    [Abstract] [Full Text] [Related]

  • 4. VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
    Muller YA, Chen Y, Christinger HW, Li B, Cunningham BC, Lowman HB, de Vos AM.
    Structure; 1998 Sep 15; 6(9):1153-67. PubMed ID: 9753694
    [Abstract] [Full Text] [Related]

  • 5. [Selection and characterization of human antibodies against vascular endothelial growth factor from human phage display antibody library].
    Tian X, Shou C, Dong Z.
    Zhonghua Yi Xue Za Zhi; 2000 Aug 15; 80(8):567-70. PubMed ID: 11798817
    [Abstract] [Full Text] [Related]

  • 6. Cross-reactive binding of cyclic peptides to an anti-TGFalpha antibody Fab fragment: an X-ray structural and thermodynamic analysis.
    Hahn M, Winkler D, Welfle K, Misselwitz R, Welfle H, Wessner H, Zahn G, Scholz C, Seifert M, Harkins R, Schneider-Mergener J, Höhne W.
    J Mol Biol; 2001 Nov 23; 314(2):293-309. PubMed ID: 11718562
    [Abstract] [Full Text] [Related]

  • 7. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H, Nie Y, Huse WD, Watkins JD.
    J Mol Biol; 1999 Nov 19; 294(1):151-62. PubMed ID: 10556035
    [Abstract] [Full Text] [Related]

  • 8. Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight.
    Covaceuszach S, Cattaneo A, Lamba D.
    Proteins; 2005 Feb 15; 58(3):717-27. PubMed ID: 15625712
    [Abstract] [Full Text] [Related]

  • 9. Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
    Mylvaganam SE, Paterson Y, Getzoff ED.
    J Mol Biol; 1998 Aug 14; 281(2):301-22. PubMed ID: 9698550
    [Abstract] [Full Text] [Related]

  • 10. Tyrosine plays a dominant functional role in the paratope of a synthetic antibody derived from a four amino acid code.
    Fellouse FA, Barthelemy PA, Kelley RF, Sidhu SS.
    J Mol Biol; 2006 Mar 17; 357(1):100-14. PubMed ID: 16413576
    [Abstract] [Full Text] [Related]

  • 11. Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries.
    Burmester J, Spinelli S, Pugliese L, Krebber A, Honegger A, Jung S, Schimmele B, Cambillau C, Plückthun A.
    J Mol Biol; 2001 Jun 08; 309(3):671-85. PubMed ID: 11397088
    [Abstract] [Full Text] [Related]

  • 12. Crystal structure of an antigen-binding fragment bound to single-stranded DNA.
    Tanner JJ, Komissarov AA, Deutscher SL.
    J Mol Biol; 2001 Dec 07; 314(4):807-22. PubMed ID: 11733999
    [Abstract] [Full Text] [Related]

  • 13. Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
    Yokoyama H, Mizutani R, Satow Y, Komatsu Y, Ohtsuka E, Nikaido O.
    J Mol Biol; 2000 Jun 09; 299(3):711-23. PubMed ID: 10835279
    [Abstract] [Full Text] [Related]

  • 14. High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.
    Lee CV, Liang WC, Dennis MS, Eigenbrot C, Sidhu SS, Fuh G.
    J Mol Biol; 2004 Jul 23; 340(5):1073-93. PubMed ID: 15236968
    [Abstract] [Full Text] [Related]

  • 15. Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody.
    Midelfort KS, Hernandez HH, Lippow SM, Tidor B, Drennan CL, Wittrup KD.
    J Mol Biol; 2004 Oct 22; 343(3):685-701. PubMed ID: 15465055
    [Abstract] [Full Text] [Related]

  • 16. Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment.
    Leonard P, Scotney PD, Jabeen T, Iyer S, Fabri LJ, Nash AD, Acharya KR.
    J Mol Biol; 2008 Dec 31; 384(5):1203-17. PubMed ID: 18930733
    [Abstract] [Full Text] [Related]

  • 17. Fabs specific for 8-oxoguanine: control of DNA binding.
    Bespalov IA, Bond JP, Purmal AA, Wallace SS, Melamede RJ.
    J Mol Biol; 1999 Nov 12; 293(5):1085-95. PubMed ID: 10547287
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity.
    Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, Rafii S.
    Leukemia; 2003 Mar 12; 17(3):604-11. PubMed ID: 12646950
    [Abstract] [Full Text] [Related]

  • 19. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC, Shan L, Goldsteen BZ, Guddat LW, Thakur A, Landolfi NF, Co MS, Vasquez M, Queen C, Ramsland PA, Edmundson AB.
    J Mol Recognit; 1999 Mar 12; 12(1):19-32. PubMed ID: 10398393
    [Abstract] [Full Text] [Related]

  • 20. The third IgG-binding domain from streptococcal protein G. An analysis by X-ray crystallography of the structure alone and in a complex with Fab.
    Derrick JP, Wigley DB.
    J Mol Biol; 1994 Nov 11; 243(5):906-18. PubMed ID: 7966308
    [Abstract] [Full Text] [Related]

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