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307 related items for PubMed ID: 10551781

  • 1. Genetic fusion of an alpha-subunit gene to the follicle-stimulating hormone and chorionic gonadotropin-beta subunit genes: production of a bifunctional protein.
    Kanda M, Jablonka-Shariff A, Sato A, Pixley MR, Bos E, Hiro'oka T, Ben-Menahem D, Boime I.
    Mol Endocrinol; 1999 Nov; 13(11):1873-81. PubMed ID: 10551781
    [Abstract] [Full Text] [Related]

  • 2. Single-chain, triple-domain gonadotropin analogs with disulfide bond mutations in the alpha-subunit elicit dual follitropin and lutropin activities in vivo.
    Jablonka-Shariff A, Kumar TR, Eklund J, Comstock A, Boime I.
    Mol Endocrinol; 2006 Jun; 20(6):1437-46. PubMed ID: 16601070
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of multi-subunit domain gonadotropin complexes: a model for alpha/beta heterodimer formation.
    Ben-Menahem D, Hyde R, Pixley M, Berger P, Boime I.
    Biochemistry; 1999 Nov 16; 38(46):15070-7. PubMed ID: 10563789
    [Abstract] [Full Text] [Related]

  • 4. Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common alpha-subunit: retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG.
    Furuhashi M, Shikone T, Fares FA, Sugahara T, Hsueh AJ, Boime I.
    Mol Endocrinol; 1995 Jan 16; 9(1):54-63. PubMed ID: 7539107
    [Abstract] [Full Text] [Related]

  • 5. Dissociation of early folding events from assembly of the human lutropin beta-subunit.
    Muyan M, Ruddon RW, Norton SE, Boime I, Bedows E.
    Mol Endocrinol; 1998 Oct 16; 12(10):1640-9. PubMed ID: 9773985
    [Abstract] [Full Text] [Related]

  • 6. Yoked complexes of human choriogonadotropin and the lutropin receptor: evidence that monomeric individual subunits are inactive.
    Narayan P, Gray J, Puett D.
    Mol Endocrinol; 2002 Dec 16; 16(12):2733-45. PubMed ID: 12456794
    [Abstract] [Full Text] [Related]

  • 7. Lys91 and His90 of the alpha-subunit are crucial for receptor binding and hormone action of follicle-stimulating hormone (FSH) and play hormone-specific roles in FSH and human chorionic gonadotropin.
    Zeng H, Ji I, Ji TH.
    Endocrinology; 1995 Jul 16; 136(7):2948-53. PubMed ID: 7540545
    [Abstract] [Full Text] [Related]

  • 8. Thyrotropin, follitropin, and chorionic gonadotropin expressed as a single multifunctional unit reveal remarkable permissiveness in receptor-ligand interactions.
    Garcia-Campayo V, Kumar TR, Boime I.
    Endocrinology; 2002 Oct 16; 143(10):3773-8. PubMed ID: 12239087
    [Abstract] [Full Text] [Related]

  • 9. Independent activities of FSH and LH structurally confined in a single polypeptide: selective modification of the relative potencies of the hormones.
    Garcia-Campayo V, Boime I.
    Endocrinology; 2001 Dec 16; 142(12):5203-11. PubMed ID: 11713216
    [Abstract] [Full Text] [Related]

  • 10. Disulfide bond mutations in follicle-stimulating hormone result in uncoupling of biological activity from intracellular behavior.
    Hiro'oka T, Maassen D, Berger P, Boime I.
    Endocrinology; 2000 Dec 16; 141(12):4751-6. PubMed ID: 11108290
    [Abstract] [Full Text] [Related]

  • 11. A single-chain tetradomain glycoprotein hormone analog elicits multiple hormone activities in vivo.
    Garcia-Campayo V, Boime I, Ma X, Daphna-Iken D, Kumar TR.
    Biol Reprod; 2005 Feb 16; 72(2):301-8. PubMed ID: 15385421
    [Abstract] [Full Text] [Related]

  • 12. Specificity of cognate ligand-receptor interactions: fusion proteins of human chorionic gonadotropin and the heptahelical receptors for human luteinizing hormone, thyroid-stimulating hormone, and follicle-stimulating hormone.
    Schubert RL, Narayan P, Puett D.
    Endocrinology; 2003 Jan 16; 144(1):129-37. PubMed ID: 12488338
    [Abstract] [Full Text] [Related]

  • 13. The position of the alpha and beta subunits in a single chain variant of human chorionic gonadotropin affects the heterodimeric interaction of the subunits and receptor-binding epitopes.
    Ben-Menahem D, Jablonka-Shariff A, Hyde RK, Pixley MR, Srivastava S, Berger P, Boime I.
    J Biol Chem; 2001 Aug 10; 276(32):29871-9. PubMed ID: 11390409
    [Abstract] [Full Text] [Related]

  • 14. A single-chain bifunctional gonadotropin analog is secreted from Chinese hamster ovary cells as two distinct bioactive species.
    Garcia-Campayo V, Jablonka-Shariff A, Boime I.
    J Biol Chem; 2004 Oct 22; 279(43):44286-93. PubMed ID: 15308629
    [Abstract] [Full Text] [Related]

  • 15. Expression and characterization of recombinant beta-subunit hCG homodimer.
    Lobel L, Pollak S, Wang S, Chaney M, Lustbader JW.
    Endocrine; 1999 Jun 22; 10(3):261-70. PubMed ID: 10484290
    [Abstract] [Full Text] [Related]

  • 16. Translational fusion of two beta-subunits of human chorionic gonadotropin results in production of a novel antagonist of the hormone.
    Roy S, Setlur S, Gadkari RA, Krishnamurthy HN, Dighe RR.
    Endocrinology; 2007 Aug 22; 148(8):3977-86. PubMed ID: 17478554
    [Abstract] [Full Text] [Related]

  • 17. Processing of O-linked glycosylation in the chimera consisting of alpha-subunit and carboxyl-terminal peptide of the human chorionic gonadotropin beta-subunit is affected by dimer formation with follicle-stimulating hormone beta-subunit.
    Furuhashi M, Suganuma N.
    Endocr J; 2004 Feb 22; 51(1):53-9. PubMed ID: 15004409
    [Abstract] [Full Text] [Related]

  • 18. Roles of N-linked and O-linked glycosylation sites in the activity of equine chorionic gonadotropin in cells expressing rat luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor.
    Lee SY, Byambaragchaa M, Choi SH, Kang HJ, Kang MH, Min KS.
    BMC Biotechnol; 2021 Sep 05; 21(1):52. PubMed ID: 34482828
    [Abstract] [Full Text] [Related]

  • 19. Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: role of a linker sequence.
    Sugahara T, Grootenhuis PD, Sato A, Kudo M, Ben-Menahem D, Pixley MR, Hsueh AJ, Boime I.
    Mol Cell Endocrinol; 1996 Dec 20; 125(1-2):71-7. PubMed ID: 9027345
    [Abstract] [Full Text] [Related]

  • 20. The carboxy-terminal region of the glycoprotein hormone alpha-subunit: contributions to receptor binding and signaling in human chorionic gonadotropin.
    Chen F, Wang Y, Puett D.
    Mol Endocrinol; 1992 Jun 20; 6(6):914-9. PubMed ID: 1379673
    [Abstract] [Full Text] [Related]

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