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151 related items for PubMed ID: 10551860

  • 1. The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis.
    Spencer AG, Thuresson E, Otto JC, Song I, Smith T, DeWitt DL, Garavito RM, Smith WL.
    J Biol Chem; 1999 Nov 12; 274(46):32936-42. PubMed ID: 10551860
    [Abstract] [Full Text] [Related]

  • 2. Photolabeling of prostaglandin endoperoxide H synthase-1 with 3-trifluoro-3-(m-[125I]iodophenyl)diazirine as a probe of membrane association and the cyclooxygenase active site.
    Otto JC, Smith WL.
    J Biol Chem; 1996 Apr 26; 271(17):9906-10. PubMed ID: 8626626
    [Abstract] [Full Text] [Related]

  • 3. C-terminal Ser/Pro-Thr-Glu-Leu tetrapeptides of prostaglandin endoperoxide H synthases-1 and -2 target the enzymes to the endoplasmic reticulum.
    Song I, Smith WL.
    Arch Biochem Biophys; 1996 Oct 01; 334(1):67-72. PubMed ID: 8837740
    [Abstract] [Full Text] [Related]

  • 4. Comparison of prostaglandin H synthase isoform structures using limited proteolytic digestion.
    Guo Q, Chang S, Diekman L, Xiao G, Kulmacz RJ.
    Arch Biochem Biophys; 1997 Aug 01; 344(1):150-8. PubMed ID: 9244392
    [Abstract] [Full Text] [Related]

  • 5. Peroxidase activity in prostaglandin endoperoxide H synthase-1 occurs with a neutral histidine proximal heme ligand.
    Seibold SA, Cerda JF, Mulichak AM, Song I, Garavito RM, Arakawa T, Smith WL, Babcock GT.
    Biochemistry; 2000 Jun 06; 39(22):6616-24. PubMed ID: 10828979
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid.
    Harman CA, Rieke CJ, Garavito RM, Smith WL.
    J Biol Chem; 2004 Oct 08; 279(41):42929-35. PubMed ID: 15292194
    [Abstract] [Full Text] [Related]

  • 7. Histidine 386 and its role in cyclooxygenase and peroxidase catalysis by prostaglandin-endoperoxide H synthases.
    Seibold SA, Ball T, Hsi LC, Mills DA, Abeysinghe RD, Micielli R, Rieke CJ, Cukier RI, Smith WL.
    J Biol Chem; 2003 Nov 14; 278(46):46163-70. PubMed ID: 12952981
    [Abstract] [Full Text] [Related]

  • 8. Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products.
    Thuresson ED, Lakkides KM, Smith WL.
    J Biol Chem; 2000 Mar 24; 275(12):8501-7. PubMed ID: 10722687
    [Abstract] [Full Text] [Related]

  • 9. The role of arginine 120 of human prostaglandin endoperoxide H synthase-2 in the interaction with fatty acid substrates and inhibitors.
    Rieke CJ, Mulichak AM, Garavito RM, Smith WL.
    J Biol Chem; 1999 Jun 11; 274(24):17109-14. PubMed ID: 10358065
    [Abstract] [Full Text] [Related]

  • 10. Prostaglandin endoperoxide H synthase-1: the functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid.
    Thuresson ED, Lakkides KM, Rieke CJ, Sun Y, Wingerd BA, Micielli R, Mulichak AM, Malkowski MG, Garavito RM, Smith WL.
    J Biol Chem; 2001 Mar 30; 276(13):10347-57. PubMed ID: 11121412
    [Abstract] [Full Text] [Related]

  • 11. Anchoring of a monotopic membrane protein: the binding of prostaglandin H2 synthase-1 to the surface of a phospholipid bilayer.
    Nina M, Bernèche S, Roux B.
    Eur Biophys J; 2000 Mar 30; 29(6):439-54. PubMed ID: 11081405
    [Abstract] [Full Text] [Related]

  • 12. The orientation of prostaglandin endoperoxide synthases-1 and -2 in the endoplasmic reticulum.
    Otto JC, Smith WL.
    J Biol Chem; 1994 Aug 05; 269(31):19868-75. PubMed ID: 8051068
    [Abstract] [Full Text] [Related]

  • 13. Distinct influences of carboxyl terminal segment structure on function in the two isoforms of prostaglandin H synthase.
    Guo Q, Kulmacz RJ.
    Arch Biochem Biophys; 2000 Dec 15; 384(2):269-79. PubMed ID: 11368314
    [Abstract] [Full Text] [Related]

  • 14. Structure-based QSAR study on differential inhibition of human prostaglandin endoperoxide H synthase-2 (COX-2) by nonsteroidal anti-inflammatory drugs.
    Pouplana R, Lozano JJ, Pérez C, Ruiz J.
    J Comput Aided Mol Des; 2002 Oct 15; 16(10):683-709. PubMed ID: 12650588
    [Abstract] [Full Text] [Related]

  • 15. Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.
    Bhattacharyya DK, Lecomte M, Rieke CJ, Garavito M, Smith WL.
    J Biol Chem; 1996 Jan 26; 271(4):2179-84. PubMed ID: 8567676
    [Abstract] [Full Text] [Related]

  • 16. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.
    Picot D, Loll PJ, Garavito RM.
    Nature; 1994 Jan 20; 367(6460):243-9. PubMed ID: 8121489
    [Abstract] [Full Text] [Related]

  • 17. Different suicide inactivation processes for the peroxidase and cyclooxygenase activities of prostaglandin endoperoxide H synthase-1.
    Song I, Ball TM, Smith WL.
    Biochem Biophys Res Commun; 2001 Dec 14; 289(4):869-75. PubMed ID: 11735127
    [Abstract] [Full Text] [Related]

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