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Journal Abstract Search

117 related items for PubMed ID: 10560739

  • 1. Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors.
    Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J.
    Bioorg Med Chem Lett; 1999 Nov 01; 9(21):3133-6. PubMed ID: 10560739
    [Abstract] [Full Text] [Related]

  • 2. Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
    Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J, Andrei G, Snoeck R, Balzarini J, De Clercq E.
    J Med Chem; 2000 Aug 24; 43(17):3267-73. PubMed ID: 10966745
    [Abstract] [Full Text] [Related]

  • 3. Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.
    Martinez A, Gil C, Castro A, Bruno AM, Pérez C, Prieto C, Otero J.
    Antivir Chem Chemother; 2003 Mar 24; 14(2):107-14. PubMed ID: 12856922
    [Abstract] [Full Text] [Related]

  • 4. Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. study of structural requirements for biological activity.
    Martinez A, Gil C, Castro A, Pérez C, Prieto C, Otero J.
    Bioorg Med Chem; 2003 May 29; 11(11):2395-402. PubMed ID: 12735985
    [Abstract] [Full Text] [Related]

  • 5. Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.
    Martinez A, Esteban AI, Castro A, Gil C, Conde S, Andrei G, Snoeck R, Balzarini J, De Clercq E.
    J Med Chem; 1999 Apr 08; 42(7):1145-50. PubMed ID: 10197958
    [Abstract] [Full Text] [Related]

  • 6. Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neuronal network techniques.
    Gil C, Dorronsoro I, Castro A, Martinez A.
    Bioorg Med Chem Lett; 2005 Apr 01; 15(7):1919-21. PubMed ID: 15780633
    [Abstract] [Full Text] [Related]

  • 7. Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.
    Pirotte B, de Tullio P, Boverie S, Michaux C, Lebrun P.
    J Med Chem; 2011 May 12; 54(9):3188-99. PubMed ID: 21428460
    [Abstract] [Full Text] [Related]

  • 8. Anti-HIV-1 activity of benzothiadiazine dioxide.
    Martinez A, Gil C, Castro A, Perez C, Witvrouw M, Pannecouque C, Balzarini J, De Clercq E.
    Antivir Chem Chemother; 2001 Nov 12; 12(6):347-51. PubMed ID: 12018679
    [Abstract] [Full Text] [Related]

  • 9. Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity.
    Pirotte B, de Tullio P, Nguyen QA, Somers F, Fraikin P, Florence X, Wahl P, Hansen JB, Lebrun P.
    J Med Chem; 2010 Jan 14; 53(1):147-54. PubMed ID: 19919106
    [Abstract] [Full Text] [Related]

  • 10. Benzothiadiazine dioxide dibenzyl derivatives as potent human cytomegalovirus inhibitors: synthesis and comparative molecular field analysis.
    Martinez A, Gil C, Abasolo MI, Castro A, Bruno AM, Perez C, Prieto C, Otero J.
    J Med Chem; 2000 Aug 24; 43(17):3218-25. PubMed ID: 10966740
    [Abstract] [Full Text] [Related]

  • 11. Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives.
    Zhan P, Liu X, De Clercq E.
    Curr Med Chem; 2008 Aug 24; 15(15):1529-40. PubMed ID: 18537628
    [Abstract] [Full Text] [Related]

  • 12. Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.
    Boverie S, Antoine MH, Somers F, Becker B, Sebille S, Ouedraogo R, Counerotte S, Pirotte B, Lebrun P, de Tullio P.
    J Med Chem; 2005 May 19; 48(10):3492-503. PubMed ID: 15887958
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and antiviral activity of novel aza-acyclonucleosides.
    Bergmeier SC, Fundy SL, Drach JC.
    Nucleosides Nucleotides; 1999 Feb 19; 18(2):227-38. PubMed ID: 10067275
    [Abstract] [Full Text] [Related]

  • 14. Studies on quinazolines and 1,2,4-benzothiadiazine 1,1-dioxides. 8.1, 2 synthesis and pharmacological evaluation of tricyclic fused quinazolines and 1,2,4-benzothiadiazine 1,1-dioxides as potential alpha1-adrenoceptor antagonists.
    Chern JW, Tao PL, Wang KC, Gutcait A, Liu SW, Yen MH, Chien SL, Rong JK.
    J Med Chem; 1998 Aug 13; 41(17):3128-41. PubMed ID: 9703460
    [Abstract] [Full Text] [Related]

  • 15. Hydroxylated analogues of ATP-sensitive potassium channel openers belonging to the group of 6- and/or 7-substituted 3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides: toward an improvement in sulfonylurea receptor 1 selectivity and metabolism stability.
    de Tullio P, Servais AC, Fillet M, Gillotin F, Somers F, Chiap P, Lebrun P, Pirotte B.
    J Med Chem; 2011 Dec 22; 54(24):8353-61. PubMed ID: 22077416
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and Pharmacology of Mono-, Di-, and Trialkyl-Substituted 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides Combined with X-ray Structure Analysis to Understand the Unexpected Structure-Activity Relationship at AMPA Receptors.
    Larsen AP, Francotte P, Frydenvang K, Tapken D, Goffin E, Fraikin P, Caignard DH, Lestage P, Danober L, Pirotte B, Kastrup JS.
    ACS Chem Neurosci; 2016 Mar 16; 7(3):378-90. PubMed ID: 26771108
    [Abstract] [Full Text] [Related]

  • 17. Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships.
    de Castro S, Andrei G, Snoeck R, Balzarini J, Camarasa MJ, Velázquez S.
    Nucleosides Nucleotides Nucleic Acids; 2007 Mar 16; 26(6-7):625-8. PubMed ID: 18066868
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and anti-HCMV activity of novel 5'-norcarboacyclic nucleosides.
    Kim A, Hong JH.
    Arch Pharm (Weinheim); 2005 Nov 16; 338(11):522-7. PubMed ID: 16281312
    [Abstract] [Full Text] [Related]

  • 19. New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors.
    Francotte P, Goffin E, Fraikin P, Lestage P, Van Heugen JC, Gillotin F, Danober L, Thomas JY, Chiap P, Caignard DH, Pirotte B, de Tullio P.
    J Med Chem; 2010 Feb 25; 53(4):1700-11. PubMed ID: 20108934
    [Abstract] [Full Text] [Related]

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