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Journal Abstract Search

162 related items for PubMed ID: 10565826

  • 1. Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism.
    Tang W, Stearns RA, Kwei GY, Iliff SA, Miller RR, Egan MA, Yu NX, Dean DC, Kumar S, Shou M, Lin JH, Baillie TA.
    J Pharmacol Exp Ther; 1999 Dec; 291(3):1068-74. PubMed ID: 10565826
    [Abstract] [Full Text] [Related]

  • 2. Cytochrome P450 3A4-mediated interaction of diclofenac and quinidine.
    Ngui JS, Tang W, Stearns RA, Shou M, Miller RR, Zhang Y, Lin JH, Baillie TA.
    Drug Metab Dispos; 2000 Sep; 28(9):1043-50. PubMed ID: 10950847
    [Abstract] [Full Text] [Related]

  • 3. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.
    Tang W, Stearns RA, Bandiera SM, Zhang Y, Raab C, Braun MP, Dean DC, Pang J, Leung KH, Doss GA, Strauss JR, Kwei GY, Rushmore TH, Chiu SH, Baillie TA.
    Drug Metab Dispos; 1999 Mar; 27(3):365-72. PubMed ID: 10064567
    [Abstract] [Full Text] [Related]

  • 4. Rifampin induces the in vitro oxidative metabolism, but not the in vivo clearance of diclofenac in rhesus monkeys.
    Prueksaritanont T, Li C, Tang C, Kuo Y, Strong-Basalyga K, Carr B.
    Drug Metab Dispos; 2006 Nov; 34(11):1806-10. PubMed ID: 16928785
    [Abstract] [Full Text] [Related]

  • 5. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 6. Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis.
    Kharasch ED, Walker A, Hoffer C, Sheffels P.
    Clin Pharmacol Ther; 2004 Nov; 76(5):452-66. PubMed ID: 15536460
    [Abstract] [Full Text] [Related]

  • 7. Pharmacokinetics and interactions of a novel antagonist of chemokine receptor 5 (CCR5) with ritonavir in rats and monkeys: role of CYP3A and P-glycoprotein.
    Kumar S, Kwei GY, Poon GK, Iliff SA, Wang Y, Chen Q, Franklin RB, Didolkar V, Wang RW, Yamazaki M, Chiu SH, Lin JH, Pearson PG, Baillie TA.
    J Pharmacol Exp Ther; 2003 Mar; 304(3):1161-71. PubMed ID: 12604693
    [Abstract] [Full Text] [Related]

  • 8. Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data.
    Yamano K, Yamamoto K, Katashima M, Kotaki H, Takedomi S, Matsuo H, Ohtani H, Sawada Y, Iga T.
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):443-52. PubMed ID: 11259329
    [Abstract] [Full Text] [Related]

  • 9. Metabolic activation of diclofenac by human cytochrome P450 3A4: role of 5-hydroxydiclofenac.
    Shen S, Marchick MR, Davis MR, Doss GA, Pohl LR.
    Chem Res Toxicol; 1999 Feb; 12(2):214-22. PubMed ID: 10027801
    [Abstract] [Full Text] [Related]

  • 10. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP, Ma J, Teffera Y, Waldon DJ.
    Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695
    [Abstract] [Full Text] [Related]

  • 11. Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.
    Lin JH, Chiba M, Chen IW, Nishime JA, Vastag KJ.
    Drug Metab Dispos; 1996 Dec; 24(12):1298-306. PubMed ID: 8971134
    [Abstract] [Full Text] [Related]

  • 12. Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat.
    Witherow LE, Houston JB.
    J Pharmacol Exp Ther; 1999 Jul; 290(1):58-65. PubMed ID: 10381760
    [Abstract] [Full Text] [Related]

  • 13. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity.
    Gorski JC, Vannaprasaht S, Hamman MA, Ambrosius WT, Bruce MA, Haehner-Daniels B, Hall SD.
    Clin Pharmacol Ther; 2003 Sep; 74(3):275-87. PubMed ID: 12966371
    [Abstract] [Full Text] [Related]

  • 14. Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes.
    Warrington JS, Poku JW, von Moltke LL, Shader RI, Harmatz JS, Greenblatt DJ.
    J Pharmacol Exp Ther; 2000 Mar; 292(3):1024-31. PubMed ID: 10688619
    [Abstract] [Full Text] [Related]

  • 15. The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy.
    Dehal SS, Brodie AM, Kupfer D.
    Drug Metab Dispos; 1999 Mar; 27(3):389-94. PubMed ID: 10064571
    [Abstract] [Full Text] [Related]

  • 16. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
    Pearce RE, Gotschall RR, Kearns GL, Leeder JS.
    Drug Metab Dispos; 2001 Dec; 29(12):1548-54. PubMed ID: 11717173
    [Abstract] [Full Text] [Related]

  • 17. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
    Quintieri L, Rosato A, Napoli E, Sola F, Geroni C, Floreani M, Zanovello P.
    Cancer Res; 2000 Jun 15; 60(12):3232-8. PubMed ID: 10866316
    [Abstract] [Full Text] [Related]

  • 18. Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.
    Chen Q, Tan E, Strauss JR, Zhang Z, Fenyk-Melody JE, Booth-Genthe C, Rushmore TH, Stearns RA, Evans DC, Baillie TA, Tang W.
    J Pharmacol Exp Ther; 2004 Oct 15; 311(1):307-14. PubMed ID: 15163679
    [Abstract] [Full Text] [Related]

  • 19. Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P-450 3A subfamily.
    Nebbia C, Ceppa L, Dacasto M, Carletti M, Nachtmann C.
    Drug Metab Dispos; 1999 Sep 15; 27(9):1039-44. PubMed ID: 10460804
    [Abstract] [Full Text] [Related]

  • 20. Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
    Yumoto R, Murakami T, Sanemasa M, Nasu R, Nagai J, Takano M.
    Drug Metab Dispos; 2001 Feb 15; 29(2):145-51. PubMed ID: 11159804
    [Abstract] [Full Text] [Related]

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