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Journal Abstract Search

541 related items for PubMed ID: 10569939

  • 1. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C, Lansiaux A, Dassonneville L, Demarquay D, Coulomb H, Huchet M, Lavergne O, Bigg DC.
    Biochemistry; 1999 Nov 23; 38(47):15556-63. PubMed ID: 10569939
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  • 2. A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.
    Bailly C, Laine W, Baldeyrou B, Demarquay D, Huchet M, Coulomb H, Lanco C, Lavergne O, Bigg DC.
    Anticancer Drug Des; 2001 Feb 23; 16(1):27-36. PubMed ID: 11762642
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  • 3. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
    Lesueur-Ginot L, Demarquay D, Kiss R, Kasprzyk PG, Dassonneville L, Bailly C, Camara J, Lavergne O, Bigg DC.
    Cancer Res; 1999 Jun 15; 59(12):2939-43. PubMed ID: 10383158
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  • 4. Activity of a novel camptothecin analogue, homocamptothecin, in camptothecin-resistant cell lines with topoisomerase I alterations.
    Urasaki Y, Takebayashi Y, Pommier Y.
    Cancer Res; 2000 Dec 01; 60(23):6577-80. PubMed ID: 11118036
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  • 5. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
    Zhu L, Zhang X, Lei N, Liu W, Miao Z, Zhuang C, Sheng C, Guo W, Dong G, Yao J, Cheng P, Zhang W.
    Chem Biodivers; 2012 Jun 01; 9(6):1084-94. PubMed ID: 22700227
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  • 6. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
    Lavergne O, Lesueur-Ginot L, Pla Rodas F, Kasprzyk PG, Pommier J, Demarquay D, Prévost G, Ulibarri G, Rolland A, Schiano-Liberatore AM, Harnett J, Pons D, Camara J, Bigg DC.
    J Med Chem; 1998 Dec 31; 41(27):5410-9. PubMed ID: 9876111
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  • 9. Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters.
    Takagi K, Dexheimer TS, Redon C, Sordet O, Agama K, Lavielle G, Pierré A, Bates SE, Pommier Y.
    Mol Cancer Ther; 2007 Dec 31; 6(12 Pt 1):3229-38. PubMed ID: 18089716
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  • 10. The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison.
    Demarquay D, Huchet M, Coulomb H, Lesueur-Ginot L, Lavergne O, Kasprzyk PG, Bailly C, Camara J, Bigg DC.
    Anticancer Drugs; 2001 Jan 31; 12(1):9-19. PubMed ID: 11272292
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  • 12. Synthesis and biological evaluation of new homocamptothecin analogs.
    Luo Y, Yu S, Tong L, Huang Q, Lu W, Chen Y.
    Eur J Med Chem; 2012 Aug 31; 54():281-6. PubMed ID: 22647222
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  • 14. Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs.
    Bailly C.
    Crit Rev Oncol Hematol; 2003 Jan 31; 45(1):91-108. PubMed ID: 12482574
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  • 15. Insilico analysis of homocamptothecin (hCPT) analogues for anti-tumour activity.
    Vadwai V, Devaraj S.
    Int J Bioinform Res Appl; 2009 Jan 31; 5(6):603-15. PubMed ID: 19887335
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  • 17. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues.
    Tardy C, Facompré M, Laine W, Baldeyrou B, García-Gravalos D, Francesch A, Mateo C, Pastor A, Jiménez JA, Manzanares I, Cuevas C, Bailly C.
    Bioorg Med Chem; 2004 Apr 01; 12(7):1697-712. PubMed ID: 15028262
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