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Journal Abstract Search

177 related items for PubMed ID: 10570051

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  • 4. Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.
    Sasaki K, Makita N, Sunami A, Sakurada H, Shirai N, Yokoi H, Kimura A, Tohse N, Hiraoka M, Kitabatake A.
    Mol Pharmacol; 2004 Aug; 66(2):330-6. PubMed ID: 15266024
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  • 6. Mexiletine Block of Voltage-Gated Sodium Channels: Isoform- and State-Dependent Drug-Pore Interactions.
    Nakagawa H, Munakata T, Sunami A.
    Mol Pharmacol; 2019 Mar; 95(3):236-244. PubMed ID: 30593458
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  • 9. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
    Ragsdale DS, McPhee JC, Scheuer T, Catterall WA.
    Proc Natl Acad Sci U S A; 1996 Aug 20; 93(17):9270-5. PubMed ID: 8799190
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  • 11. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
    Wright SN, Wang SY, Wang GK.
    Mol Pharmacol; 1998 Oct 20; 54(4):733-9. PubMed ID: 9765517
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  • 12. Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.
    De Luca A, Natuzzi F, Falcone G, Duranti A, Lentini G, Franchini C, Tortorella V, Camerino DC.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Dec 20; 356(6):777-87. PubMed ID: 9453464
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  • 16. Prenylamine block of Nav1.5 channel is mediated via a receptor distinct from that of local anesthetics.
    Mujtaba MG, Wang SY, Wang GK.
    Mol Pharmacol; 2002 Aug 20; 62(2):415-22. PubMed ID: 12130695
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  • 17. Combined application of class I antiarrhythmic drugs causes "additive", "reductive", or "synergistic" sodium channel block in cardiac muscles.
    Kawamura T, Kodama I, Toyama J, Hayashi H, Saito H, Yamada K.
    Cardiovasc Res; 1990 Nov 20; 24(11):925-31. PubMed ID: 2176934
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  • 18. Different effects of mexiletine on two mutant sodium channels causing paramyotonia congenita and hyperkalemic periodic paralysis.
    Weckbecker K, Würz A, Mohammadi B, Mansuroglu T, George AL, Lerche H, Dengler R, Lehmann-Horn F, Mitrovic N.
    Neuromuscul Disord; 2000 Jan 20; 10(1):31-9. PubMed ID: 10677861
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  • 19. Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n - 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes.
    Kang JX, Li Y, Leaf A.
    Proc Natl Acad Sci U S A; 1997 Mar 18; 94(6):2724-8. PubMed ID: 9122264
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  • 20. A model analysis for competitive binding of mexiletine and aprindine to the cardiac sodium channel.
    Kamiya K, Toyama J, Honjo H, Kodama I.
    Pharmacology; 1992 Mar 18; 44(5):260-8. PubMed ID: 1320276
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