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141 related items for PubMed ID: 10570053

  • 1. Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.
    Gorboulev V, Volk C, Arndt P, Akhoundova A, Koepsell H.
    Mol Pharmacol; 1999 Dec; 56(6):1254-61. PubMed ID: 10570053
    [Abstract] [Full Text] [Related]

  • 2. Cloning and characterization of two human polyspecific organic cation transporters.
    Gorboulev V, Ulzheimer JC, Akhoundova A, Ulzheimer-Teuber I, Karbach U, Quester S, Baumann C, Lang F, Busch AE, Koepsell H.
    DNA Cell Biol; 1997 Jul; 16(7):871-81. PubMed ID: 9260930
    [Abstract] [Full Text] [Related]

  • 3. Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
    Arndt P, Volk C, Gorboulev V, Budiman T, Popp C, Ulzheimer-Teuber I, Akhoundova A, Koppatz S, Bamberg E, Nagel G, Koepsell H.
    Am J Physiol Renal Physiol; 2001 Sep; 281(3):F454-68. PubMed ID: 11502595
    [Abstract] [Full Text] [Related]

  • 4. Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
    Busch AE, Quester S, Ulzheimer JC, Waldegger S, Gorboulev V, Arndt P, Lang F, Koepsell H.
    J Biol Chem; 1996 Dec 20; 271(51):32599-604. PubMed ID: 8955087
    [Abstract] [Full Text] [Related]

  • 5. Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone.
    Volk C, Gorboulev V, Kotzsch A, Müller TD, Koepsell H.
    Mol Pharmacol; 2009 Aug 20; 76(2):275-89. PubMed ID: 19435783
    [Abstract] [Full Text] [Related]

  • 6. Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake.
    Gorboulev V, Rehman S, Albert CM, Roth U, Meyer MJ, Tzvetkov MV, Mueller TD, Koepsell H.
    Mol Pharmacol; 2018 Apr 20; 93(4):402-415. PubMed ID: 29339398
    [Abstract] [Full Text] [Related]

  • 7. A reevaluation of substrate specificity of the rat cation transporter rOCT1.
    Nagel G, Volk C, Friedrich T, Ulzheimer JC, Bamberg E, Koepsell H.
    J Biol Chem; 1997 Dec 19; 272(51):31953-6. PubMed ID: 9405386
    [Abstract] [Full Text] [Related]

  • 8. Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.
    Feng B, Dresser MJ, Shu Y, Johns SJ, Giacomini KM.
    Biochemistry; 2001 May 08; 40(18):5511-20. PubMed ID: 11331016
    [Abstract] [Full Text] [Related]

  • 9. The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization.
    Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H.
    J Biol Chem; 2011 Oct 28; 286(43):37874-86. PubMed ID: 21896487
    [Abstract] [Full Text] [Related]

  • 10. Cloning and functional expression of a human liver organic cation transporter.
    Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM.
    Mol Pharmacol; 1997 Jun 28; 51(6):913-21. PubMed ID: 9187257
    [Abstract] [Full Text] [Related]

  • 11. The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.
    Goralski KB, Lou G, Prowse MT, Gorboulev V, Volk C, Koepsell H, Sitar DS.
    J Pharmacol Exp Ther; 2002 Dec 28; 303(3):959-68. PubMed ID: 12438515
    [Abstract] [Full Text] [Related]

  • 12. Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).
    Friedrich A, George RL, Bridges CC, Prasad PD, Ganapathy V.
    Biochim Biophys Acta; 2001 Jun 06; 1512(2):299-307. PubMed ID: 11406107
    [Abstract] [Full Text] [Related]

  • 13. Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.
    Sturm A, Gorboulev V, Gorbunov D, Keller T, Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H.
    Am J Physiol Renal Physiol; 2007 Sep 06; 293(3):F767-79. PubMed ID: 17567940
    [Abstract] [Full Text] [Related]

  • 14. Role of organic cation transporters in the renal secretion of nucleosides.
    Chen R, Nelson JA.
    Biochem Pharmacol; 2000 Jul 15; 60(2):215-9. PubMed ID: 10825466
    [Abstract] [Full Text] [Related]

  • 15. Acidic residues involved in cation and substrate interactions in the Na+/dicarboxylate cotransporter, NaDC-1.
    Griffith DA, Pajor AM.
    Biochemistry; 1999 Jun 08; 38(23):7524-31. PubMed ID: 10360950
    [Abstract] [Full Text] [Related]

  • 16. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.
    Gorboulev V, Shatskaya N, Volk C, Koepsell H.
    Mol Pharmacol; 2005 May 08; 67(5):1612-9. PubMed ID: 15662045
    [Abstract] [Full Text] [Related]

  • 17. The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1.
    Zhang L, Gorset W, Dresser MJ, Giacomini KM.
    J Pharmacol Exp Ther; 1999 Mar 08; 288(3):1192-8. PubMed ID: 10027858
    [Abstract] [Full Text] [Related]

  • 18. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
    Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H.
    J Membr Biol; 2002 Oct 01; 189(3):237-44. PubMed ID: 12395288
    [Abstract] [Full Text] [Related]

  • 19. Cloning and functional expression of a mouse liver organic cation transporter.
    Green RM, Lo K, Sterritt C, Beier DR.
    Hepatology; 1999 May 01; 29(5):1556-62. PubMed ID: 10216142
    [Abstract] [Full Text] [Related]

  • 20. Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
    Okuda M, Urakami Y, Saito H, Inui K.
    Biochim Biophys Acta; 1999 Mar 04; 1417(2):224-31. PubMed ID: 10082798
    [Abstract] [Full Text] [Related]

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